Saitama (One Punch Man) Saitama's strength and speed far outstrip even the Mad Titan's own, and these abilities would allow Saitama to easily overcome Thanos's regenerative abilities.
Against the MCU Avengers, Saitama stomps most of them.
In the One Punch Man universe, Saitama is by far the strongest being who surpassed his limit breaker a long time ago. His cosmic levels of strength have led many to believe that the series protagonist will be able to lift Mjolnir by overcoming the charm placed around it with nothing but brute force.
While Thanos is an Eternal and has the standard powers of super-strength, agility, regeneration, immortality, and more, Adam Warlock takes the upper hand. He can be killed, but he resurrects to be stronger every time.
While the MCU Hulk was not able to defeat Thanos, his comic book counterparts pose a better chance to make an even fight particularly if Thanos does not wield the Infinity Gauntlet. These two titans in the Marvel Universe seem destined to do battle in some form or another.
However, Ultron, who was fascinated with the Stones, effortlessly killed Thanos by cutting his body in half with a laser beam from the Mind Stone and obtained all the Stones for himself which turned him into a cosmic being.
Saitama vs cat
[ Still trying to do the math on how, the only thing to ever actually damage Saitama in the series is a cat scratching his face.
Goku is an extraterrestrial being who has to lose a fight in order to get stronger. Saitama is a man that can defeat any foe with a single punch. If the two of them were to face off in a one-on-one battle, Saitama would easily win.
Secondly, some people claim that the writer of OPM(One) has said that the limit of Saitama's power is that he can destroy half a universe with one full-powered punch. This isn't true. One has never said anything like that, and it is only a rumor.
Can Saitama lift 200 quintillion? Gravity is about 1/5th as strong as Earth's on Io, so with a mass of 89.3 x 10^21 kg (half of Io canceling out the one-handedness), Saitama at the time could probably effortlessly lift 16 quintillion tons on Earth.
A key advantage that Hulk has over Saitama is his ability to heal/regenerate himself. Hulk has one of the strongest healing factors in all of Marvel, rivaling even Wolverine's ability to heal. This is not a power that Saitama is ever shown to have.
Saitama might be powerful, but even his physical strength cannot match Goku's strength. It should also be noted how Goku's Ultra instinct essentially scared the gods of destruction. Whether they're in the One Punch Man or Dragon Ball universe, Goku would easily be able to kill Saitama without much effort.
Thanos has the infinity gauntlet with all six infinity stones (gems). If he “retires”, like like he does after snapping away half of life (movie Infinity War), then he is no longer in possession of the six infinity stones powers, and will definitely not be able to beat Saitama.
Saitama (One Punch Man)
Saitama's strength and speed far outstrip even the Mad Titan's own, and these abilities would allow Saitama to easily overcome Thanos's regenerative abilities.
In the end, unless Clark is capable of defeating Saitama in the early stages of their fight, Saitama will be the clear victor. Not only does his limitless potential help him surpass Clark's power, but he could also last longer in combat.
Saitama (1000 IQ) VS 1.000. 000 Colossal Titans: 1.000 IQ, 100 IQ, 10 IQ!
According to Saitama, he achieved immense strength by performing 100 push-ups, 100 squats, 100 sit-ups, and running 10 kilometers daily for about a year.
He exhibits the same strength effortlessly and yet still has more room for growth. At this point, he hasn't ever needed to use his full power, whereas Goku frequently needs to reach his limits. All in all, Saitama wins this competition.
Can Saitama survive a nuke? He can survive a nuclear bomb, probably, sure, but Saitama's fist is a concentrated nuke at minimum power. This would knock Accelerator out instantly just from the sheer surprising force put into the attack overloading his inferior vector changing.
The Marvel comics establish the Hulk as possessing limitless physical strength and endurance, which could easily withstand a few (if not all) of Saitama's punches.
In 2014, Nebula and Gamora, under orders from Thanos, are dispatched to assist Ronan the Accuser in obtaining the Power Stone. After learning Gamora has it, Nebula goes to Knowhere and shoots her pod down and takes the Stone for Ronan, who then betrays Thanos, intending to destroy the planet Xandar and kill Thanos.
Ronan betrays Thanos after he connects the Orb to his Universal Weapon, a war hammer given to him by the Exolon Monks. He decides to invade Xandar to avenge his ancestors.
And Here's Why. In Thor vol. 2 #25, the God of Thunder defeated the Mad Titan with the help of Fire Lord, who provided him with a set of special Asgardian weapons, including Belt of Strength, Odin Force, and more. Ultimately, Thor defeated Thanos with his trusted Mjolnir by smashing Mad Titan.