4 The study also found that the participants who were taking an antidepressant experienced stronger benefits when taking magnesium, which suggests that it might be useful when used in conjunction with antidepressant medications.
John's wort, garcinia cambogia, L-tryptophan (or 5-HTP) and SAMe (S-adenosyl-methionine) supplements with your antidepressant. Consumer Labs says they can increase your risk of experiencing serotonin syndrome.
Antibiotics: Taking magnesium supplements may reduce the absorption of quinolone antibiotics, tetracycline antibiotics, and nitrofurantoin (Macrodandin). Magnesium should be taken 1 hour before or 2 hours after taking these medications. Quinolone and tetracycline antibiotics include: Ciprofloxacin (Cipro)
Magnesium works as an important co-factor required for conversion of tryptophan (from proteins we get from food) to serotonin and melatonin, both of which help in falling asleep."
Magnesium and drugs use the same transport and metabolism pathways in the body for their intestinal absorption, metabolism, and elimination. This means that when one or more drug is taken, there is always a potential risk of interaction with the magnesium status.
Interactions between your drugs
No interactions were found between calcium carbonate / magnesium chloride and Zoloft.
Magnesium also modulates activity of the hypothalamic pituitary adrenal axis (HPAA) which is a central substrate of the stress response system. Activation of the HPAA instigates adaptive autonomic, neuroendocrine, and behavioral responses to cope with the demands of the stressor; including increasing anxiety.
However, magnesium inhibits dopamine release. Therefore, magnesium may inhibit calcium-dependent brain function through dopaminergic neurons, and consequently reduce the effect of calcium on ethanol activity.
With respect to mechanisms of action, Mg affects a number of neurotransmitter systems. It inhibits the release of excitatory neuro- transmitters and also acts as a voltage-gated antagonist at the glutamate, N-methyl-D- aspartate (NMDA) receptor. Mg also antagonizes calcium entry via voltage-gated channels of all types.
Antibiotics -- The absorption of quinolone antibiotics, such as ciprofloxacin (Cipro) and moxifloxacin (Avelox), tetracycline antibiotics, including tetracycline (Sumycin), doxycycline (Vibramycin), and minocycline (Minocin), and nitrofurantoin (Macrodandin), may be diminished when taking magnesium supplements.
Magnesium does not react with water to any significant extent. This is in contrast with calcium, immediately below magnesium in the periodic table, which does react slowly with cold water.
High doses of magnesium from supplements or medications can cause nausea, abdominal cramping and diarrhea. In addition, the magnesium in supplements can interact with some types of antibiotics and other medicines.
Some of the medicines that can interact with some SSRIs include: non-steroidal anti-inflammatory drugs (NSAIDs) – a common type of painkiller that includes ibuprofen, diclofenac or naproxen. antiplatelets – a type of medicine used to prevent blood clots, such as low-dose aspirin and clopidogrel.
It is perfectly ok to take a multi-vitamin while taking prescription medications for depression and anxiety. But never take more than the recommended daily allowance of any vitamin.
In magnesium deficiency, neuronal requirements for magnesium may not be met, causing neuronal damage which could manifest as depression.
Magnesium can also reduce physiological symptoms like headaches, muscle pain, back pain, and stomach pain. In addition, magnesium benefits mental health by acting as a mood booster, muscle relaxer, stress reducer, and sleep aid.
Magnesium is an essential mineral that is involved in various aspects of physical and mental health. Recent research has found that consuming sufficient amounts of magnesium may help reduce stress, anxiety, and depression.
The lowdown. Medical research has linked magnesium to reduced anxiety. Magnesium helps you to relax by stimulating the production of melatonin and serotonin which boost your mood and help you sleep. Magnesium also reduces the production of cytokines and cortisol, which lead to increased inflammation and stress.
Magnesium yields opposite effects on the nuclear and cytosolic cascades of apoptosis in different rat brain regions. Eur Rev Med Pharmacol Sci. 2022 Sep;26(18):6523-6535.
sertraline magnesium citrate
You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with these medications.
Do not use sertraline with buspirone (Buspar®), fentanyl (Abstral®, Duragesic®), linezolid (Zyvox®), lithium (Eskalith®, Lithobid®), methylene blue injection, tryptophan, St John's wort, or some pain or migraine medicines (eg, rizatriptan, sumatriptan, tramadol, Frova®, Imitrex®, Maxalt®, Relpax®, Ultram®, Zomig®).
No interactions were found between fluoxetine and Mag-200.