OTC fish oil supplements are not better for treating high cholesterol than statins. People can use OTC fish oil supplements to support their general health. However, the FDA have not approved fish oil dietary supplements to treat any specific medical condition.
There's strong evidence that omega-3 fatty acids can significantly reduce blood triglyceride levels. There also appears to be a slight improvement in high-density lipoprotein (HDL, or "good") cholesterol, although an increase in levels of low-density lipoprotein (LDL, or "bad") cholesterol also was observed.
Ezetimibe. Ezetimibe is a tablet that lowers cholesterol. It may be prescribed if statins cannot be taken, or alongside a statin for extra cholesterol-lowering. It's a 'cholesterol absorption inhibitor' that limits the absorption of cholesterol in the small intestine.
Expert Analysis. All individuals should aim to consume approximately 2 servings of fatty fish per week as part of a heart-healthy diet. Routine use of non-prescription fish oil is not recommended for primary or secondary prevention of CVD.
In summary, fish oil may reduce atherosclerosis by activating numerous nuclear receptors including PPAR-alpha and PPAR-gamma, by inhibiting the infiltration of macrophages and as the release of MMPs, and by preventing the weakening and rupturing of atherosclerotic plaque.
People taking blood pressure medication should talk to a doctor before trying these supplements. Blood clotting: Omega-3s might also affect blood clotting, so people with clotting disorders, bleeding disorders, and those taking clotting medication should talk to a doctor before supplementing with fish oil.
Fibrates. Doctors often prescribe a fibrate for patients who can't take a statin. Like the statins, fibrates reduce the body's cholesterol production, but they are less effective in lowering LDL cholesterol levels.
If you're taking a statin medication to lower your cholesterol, you will need to keep taking your prescription, or your cholesterol will likely go back up. Stopping your statin can put you at risk of having heart disease and other preventable health problems like stroke and heart attack from high cholesterol.
When taken by mouth: Fish oil is likely safe for most people in doses of 3 grams or less daily. Taking more than 3 grams daily might increase the chance of bleeding. Fish oil side effects include heartburn, loose stools, and nosebleeds. Taking fish oil supplements with meals or freezing them can reduce these issues.
Nordic Naturals Ultimate Omega is our pick for the best overall because it's a high quality supplement that provides 1,100 mg of combined EPA and DHA sourced from wild-caught sardines and anchovies. The softgels are lemon-flavored, which can help eliminate the fishy aftertaste often found in other fish oil supplements.
According to a research review people who take simvastatin (Zocor) or pravastatin (Pravachol) may experience fewer side effects.
Oatmeal, oat bran and high-fiber foods
Soluble fiber is also found in such foods as kidney beans, Brussels sprouts, apples and pears. Soluble fiber can reduce the absorption of cholesterol into your bloodstream. Five to 10 grams or more of soluble fiber a day decreases your LDL cholesterol.
Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-my-OL-ih-sis). Rhabdomyolysis can cause severe muscle pain, liver damage, kidney failure and death. The risk of very serious side effects is extremely low, and calculated in a few cases per million people taking statins.
Low-density lipoprotein (LDL) cholesterol.
The most important thing your doctor will keep in mind when thinking about statin treatment is your long-term risk of a heart attack or stroke. If your risk is very low, you probably won't need a statin, unless your LDL is above 190 mg/dL (4.92 mmol/L).
The cholesterol-lowering action of alternate-day statins is as effective as daily dosing in many individuals. 6.
Statins are the most common medicine for high cholesterol. They reduce the amount of cholesterol your body makes. You take a tablet once a day. You usually need to take them for life.
Omega-3s from fish and fish oil have been recommended by the American Heart Association (AHA) for the past 20 years to reduce cardiovascular events, like heart attack or stroke, in people who already have cardiovascular disease (CVD).
Fish oil contains omega-3 fatty acids, which can help lower triglyceride levels and break up other fats within your body. This can result in lower blood pressure and a reduced risk of other cardiovascular problems, such as heart attack or stroke.
Fish oil supplements are a popular alternative for those looking to relieve joint pain. It is made up of omega-3 fatty acids which contain anti-inflammatory properties. These fatty acids play a role in providing pain relief to many of your body's joints.