Liver injury due to warfarin therapy is rare, but clinically apparent acute liver injury attributable to it has been reported. Liver injury is more common with other coumarin derivatives such as
Early Signs of Liver Damage from Medication
Fever. Diarrhea. Dark urine. Jaundice, a condition that occurs when a substance called bilirubin builds up in the blood and causes the skin and whites of the eyes to appear yellow.
Warfarin has traditionally been the anticoagulant agent of choice for the treatment and prevention of thrombotic complications in patients with liver disease.
In a Kaplan‐Meier analysis, patients who were treated with warfarin had a mean life expectancy of 52.0 months, whereas those who were not treated with warfarin had a corresponding life expectancy of 38.2 months (Δ = 13.8 months, p < 0.001) (fig 1).
Aside from bleeding-related issues, there are several side effects that have been linked to blood thinners, such as nausea and low counts of cells in your blood. Low blood cell count can cause fatigue, weakness, dizziness and shortness of breath. Be careful mixing medications.
Grapefruit and other citrus fruits can interfere with how your body metabolizes these medications.
Acetaminophen. Taking acetaminophen in excess is the leading cause of drug-induced liver injury. “When you follow recommended acetaminophen doses, the drug is very safe,” said Francisco Durazo, MD, chief of transplant hepatology and transplant medicine at the Froedtert & MCW health network.
Life with blood thinners can be overwhelming at first, but eventually, you can still live a very normal life with these medications. Blood thinners do not actually thin your blood, and they do not heal or dissolve blood clots.
Types of anticoagulants
The most commonly prescribed anticoagulant is warfarin.
If you are a heart patient who is taking blood thinners, such as warfarin (Coumadin®), you need to be careful not to overdo vitamin K. Blood thinners are often prescribed for people at risk for developing harmful blood clots. If you suddenly increase your intake of vitamin K, it can have an unintended consequence.
After stopping warfarin your blood will return to normal in a few days. Don't stop taking warfarin unless told by your doctor. If you stop taking warfarin before it is safe you are at risk of having clots forming in your blood.
French fries, wafers, burgers, and pizzas do no good to your liver. These food items are high in saturated fat or trans-fat content and are difficult to digest. In other words, your liver needs to work hard to process these food items.
Too Much Alcohol
Alcoholic fatty liver, which causes liver inflammation (alcoholic hepatitis), eventual scarring (cirrhosis) and even liver cancer, is a process that begins on as little as four drinks a day for men and two for women. By the time you show symptoms, your liver may be damaged beyond repair.
Foods that support liver health include berries, cruciferous vegetables, beans, whole grains, nuts, and fatty fish. Coffee and green tea contain antioxidants that are helpful for liver health.
A liver blood test measures the levels of various things in your blood, like proteins, liver enzymes, and bilirubin. This can help check the health of your liver and for signs of inflammation or damage.
Paracetamol is a common painkiller that is normally safe. If you take more than the recommended amount (an overdose), it can harm the liver and rarely the kidneys.
Life Expectancy With Fatty Liver Diseases
People stay healthy despite suffering from the disease following a normal routine. The life expectancy with fatty liver disease decreases from 3 to 4 years because such patients develop other chronic diseases such as cardiovascular or diabetes.
Dense with nutrients, broccoli is a healthy addition to any balanced diet. However, if you have a condition that requires you to take blood-thinning medication, you might want to be cautious. Broccoli doesn't thin your blood, but the vitamin K in broccoli can inhibit your anticoagulant medication.
The reason? Spinach, kale, and other leafy greens are all rich in vitamin K, which plays an essential role in forming blood clots. Warfarin (the generic name for Coumadin) helps prevent blood clots by blocking vitamin K's actions.
On the positive side, patients are able to consume many foods considered safe if they are taking any anticoagulants. These are the foods that are considered safe to consume: Meat, fish, and eggs. Milk, cheese, and yogurt.