Vitamin B12 deficiency may lead to symptoms of fatigue and tiredness. Vitamin B12 has been observed to work directly on the pineal gland to promote the production of melatonin and help it release into the bloodstream earlier. This helps you fall asleep on time and stay asleep during the night.
In particular, vitamins B6, B12, C, D, and E can improve or lower your sleep quality and duration. Vitamin C deficiency and both lack and an excess of vitamin B6 in the body might affect your sleep or cause insomnia. It is important, therefore, that you consult your doctor before taking any vitamin supplements.
Vitamin B12 helps increase the body's production of melatonin, making it important for regulating sleep-wake cycles.
Vitamin B12
As a general rule of thumb, take your B vitamins in the morning or with a meal. Vitamin B12, for example, should definitely be taken in the morning. This is because it is important for energy metabolism, which may interrupt your sleep if taken at night.
More Serious Effects
B12 injections may contribute to low potassium levels in your body. Though rare, this reaction can cause muscle cramping, extreme fatigue, and an irregular heartbeat.
Vitamin B-12 can cause very rare but serious allergic reactions (anaphylaxis). This includes swelling of the face, tongue, and throat, and difficulty swallowing and breathing. If this occurs after you take vitamin B-12, call 911 or your local emergency services immediately.
It may take a few weeks before your vitamin B12 levels and symptoms (such as extreme tiredness or lack of energy) start to improve. If you have hydroxocobalamin injections to boost your vitamin B12 levels at the start of treatment, the cyanocobalamin tablets may start to work within a few days.
Vitamin C (ascorbic acid) supplements.
Taking vitamin B-12 with vitamin C might reduce the available amount of vitamin B-12 in your body. To avoid this interaction, take vitamin C two or more hours after taking a vitamin B-12 supplement.
Fat-soluble and water-soluble vitamins
Some combinations should be avoided, even if they aren't inherently problematic. For example, although it's safe to take vitamin D with vitamin B12, it's not advisable, says Virgilio Sanchez, MD, a board certified family medicine physician at Conviva Care Center in Miami, Florida.
There is no risk of an overdose when taking large amounts of vitamin B-12 such as 1000 mcg, because it is a water-soluble vitamin. Meaning the body will use the amount that it needs then the excess will be excreted through urine.
In contrast to this study, our results show that vitamin B complex, in combination with magnesium and melatonin, has a positive effect on sleep regulation and can be used to treat insomnia.
Physical causes of tiredness
There are several health conditions that can make you feel tired or exhausted. These include: iron deficiency anaemia. underactive thyroid (hypothyroidism)
Magnesium
Magnesium is perhaps the most important vitamin or mineral when it comes to sleep. It plays a key role in the bodily function that regulates sleep and studies have shown that sleep suffers without optimal vitamin intake.
“Take water-soluble vitamins on an empty stomach with a glass of water,” recommends Dr. Perez-Gallardo. And since it can be energizing, Dr. Perez-Gallardo says that the best time to take vitamin B12 is in the morning, so it won't affect your sleep.
Yes, as B vitamins and magnesium don't compete for absorption inside your body. Indeed, many supplements combine them as a way of simplifying how you monitor your intake. Vitamin B and magnesium work in tandem to: promote normal function of the nervous system and normal psychological function.
Vitamin B complex.
There is some evidence that taking a daily capsule containing eight B vitamins—B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6, B7 (biotin), B9 (folate), and B12—may prevent cramps.
Vitamin C and B12
According to Dr. Airey, some studies have shown that Vitamin C could break down Vitamin B12 in your digestive tract, reducing your B12 absorption. As a result, he says you want to wait at least two hours before taking Vitamin C with your Vitamin B12.
Vitamin B12 is a water-soluble vitamin, and the risks of dose-related side effects are low. Your body can usually get rid of excess vitamin B12 through your urine. In rare cases, high doses of vitamin B12 injections have been associated with skin reactions. This isn't the case for oral vitamin B12 dietary supplements.
[1] People who regularly take medications that suppress stomach acid for conditions like gastroesophageal reflux disease (GERD) or peptic ulcer disease—such as proton-pump inhibitors, H2 blockers, or other antacids—may have difficulty absorbing vitamin B12 from food.
The Mental Health/B12 Link
Having a B12 deficiency puts you at risk for developing depression and anxiety, fatigue, and can worsen hypothyroid and other health concerns.
Monitoring your condition
A blood test is often carried out around 10 to 14 days after starting treatment to assess whether treatment is working. This is to check your haemoglobin level and the number of the immature red blood cells (reticulocytes) in your blood.
extreme tiredness (fatigue) lack of energy (lethargy) breathlessness. feeling faint.
Key points about vitamin B12 deficiency anemia
Without enough oxygen, your body can't work as well. Symptoms include weak muscles, numbness, trouble walking, nausea, weight loss, irritability, fatigue, and increased heart rate.
Despite the numerous processes in which vitamin B12 is involved, there's little evidence to suggest that it has any influence on weight gain or loss.
The two most likely reasons you're always so tired no matter how much sleep you get are you've got high sleep debt or you're not living in sync with your circadian rhythm. You may also feel sleepy if you're ill, pregnant, or you've got a medical condition like anemia or diabetes.