Ebola Outbreaks By far the deadliest outbreak occurred in 2014-2016 when more than 11,000 people died (most in west African Guinea, Liberia and Sierra Leone). More than 2,000 people died during the second largest outbreak to date, from 2018 to 2020, in the Democratic Republic of Congo.
In 2014, an EVD outbreak was reported for the first time in West Africa (Guinea, Liberia and Sierra Leone). During this outbreak, which was ongoing between 2014 and 2016, there was intense transmission in urban areas, resulting in over 28,000 reported cases.
Visit the Ebola Outbreak section for information on current Ebola outbreaks. The largest Ebola outbreak in history was first reported in March 2014 and declared over by the World Health Organization (WHO) on June 10, 2016.
Occurred in the Orientale Province. This was the most severe Ebola outbreak in recorded history in regards to both the number of human cases and fatalities. It began in Guéckédou, Guinea, in December 2013 and spread abroad. Flare-ups of the disease continued into 2016, and the outbreak was declared over on 9 June 2016.
Between 1976 and 2012, according to the World Health Organization, there were 24 outbreaks of Ebola resulting in a total of 2,387 cases, and 1,590 deaths. The largest Ebola outbreak to date was an epidemic in West Africa from December 2013 to January 2016, with 28,646 cases and 11,323 deaths.
Ebola virus disease is a rare illness which can cause death. The Ebola virus isn't found in Australia. The Ebola virus is transmitted (spread) through contact with bodily fluids.
Treatment centres and isolation zones were set up to reduce the spread of the virus and face-masks, gowns and gloves were used. Safe burial practices also helped to limit transmission of the virus, as did screening of passengers at international and domestic ports and airports.
Currently Ebola is not considered a threat outside of certain countries in sub-Saharan Africa. Very few people with Ebola have been outside of that area. During the 2014-2016 outbreak, 11 people with Ebola were treated in the United States, nine of whom had contracted it in western Africa, most as health care workers.
There's no cure for Ebola, though researchers are working on it. There are two drug treatments which have been approved for treating Ebola. Inmazeb is a mixture of three monoclonal antibodies (atoltivimab, maftivimab, and odesivimab-ebgn). Ansuvimab-zykl (Ebanga) is a monoclonal antibody given as an injection.
Most people affected by the outbreak were in Guinea, Sierra Leone, and Liberia. There were also cases reported in Nigeria, Mali, Europe, and the U.S. 28,616 people were suspected or confirmed to be infected; 11,310 people died. Ebola is spread by contact with bodily fluids of infected animals or humans.
ERVEBO® (Ebola Zaire Vaccine, Live also known as V920, rVSVΔG-ZEBOV-GP or rVSV-ZEBOV) is approved by the U.S. Food and Drug Administration (FDA) for the prevention of disease caused by Ebola virus (EBOV; species Zaire ebolavirus) in individuals 18 years of age and older as a single dose administration.
Since EVD was first characterized in 1976, there have been 38 country-specific outbreaks, including the outbreak in the DRC. The total estimated EVD deaths from 1976 to 2020 is 15,266. The median number of deaths for all 38 outbreaks is 29 with a range of 0 to 4,809 (Table 1).
Following the discovery of these ebolaviruses, scientists studied thousands of animals, insects, and plants in search of the source, or reservoir host. It is believed that African fruit bats are likely involved in the spread of ebolaviruses and may even be the reservoir host.
On November 7, 2015, 42 days after the last patient with Ebola was confirmed to test negative for the disease, the World Health Organization declared the end of the Ebola outbreak in Sierra Leone.
While Ebola has predominantly been observed in countries within Africa, COVID-19 has become a worldwide epidemic, affecting over 200 countries and territories including over 1.9 million cases within the U.S. While the mortality observed in COVID-19 is substantially lower than in EVD, the transmission risk primarily ...
Ebolaviruses also can be killed by many common chemical agents. Chemical agents that will kill the virus include bleach, detergents, solvents, alcohols, ammonia, aldehydes, halogens, peracetic acid, peroxides, phenolics, and quaternary ammonium compounds.
Scientists at La Jolla Institute for Immunology (LJI) have uncovered the structure and function of the first FDA-approved treatment for Zaire ebolavirus (Ebola virus). Inmazeb (REGN-EB3), developed by Regeneron, is a three-antibody cocktail designed to target the Ebola virus glycoprotein.
One major difference between Ebola and COVID-19 is the method of spread. Ebola is spread during the last stage of the disease through blood and sweat. In contrast, COVID-19 spreads more easily through breathing, coughing or talking in close contact.
Ebola disease is caused by an infection with one of a group of viruses, known as ebolaviruses, that are found primarily in sub-Saharan Africa.
The average EVD case fatality rate is around 50%. Case fatality rates have varied from 25% to 90% in past outbreaks. Community engagement is key to successfully controlling outbreaks.
Today, the COVID-19 pandemic is frequently compared with the influenza pandemic of 1918-1919. The destruction caused by that pandemic a century ago may sound familiar.
dementia, including Alzheimer's disease. advanced lung, heart, kidney and liver disease. stroke and other neurological diseases, including motor neurone disease and multiple sclerosis. Huntington's disease.
Cardiovascular disease is the top cause of death globally. In the map we see death rates from cardiovascular diseases across the world.