Tizanidine (Zanaflex) A muscle relaxant can reduce stiffness and spasms and may be particularly useful to treat painful night-time spasms. Because its effects last for only 3-6 hours, it can be best used around specific times when relief from symptoms is most important, for example at bedtime.
Baclofen (Lioresal, Gablofen)
Baclofen is a skeletal muscle relaxant used as a first-line treatment for spasticity in patients with MS. It can effectively relieve spasms and has modest effects in improving performance. Intrathecal baclofen via an implanted pump can be effective against spasticity in suitable patients.
Baclofen is the most commonly prescribed medication to treat spasticity in MS and is usually very effective. It may be taken orally, or for individuals with more severe spasticity, given via an implanted pump that provides the medicine directly into the spinal fluid.
Muscle relaxants.
Muscle relaxants such as baclofen (Lioresal, Gablofen), tizanidine (Zanaflex) and cyclobenzaprine may help. Onabotulinumtoxin A treatment is another option in those with spasticity.
Ocrevus and Tysabri account for over 85% of the patient share of multiple sclerosis medications.
Over-the-counter pain relievers such as nonsteroidal anti-inflammatory drugs (NSAIDs), like Aleve (naproxen) and Advil (ibuprofen), can treat musculoskeletal pain and headaches common with MS. These medications can relieve pain and lower inflammation in the body, which can also help with the pain associated with MS.
One study noted young people with MS who took a calcium, vitamin D, and magnesium supplement had a reduced number of relapses. The study authors theorized that magnesium could play a role in the growth and stability of myelin.
Strength exercises such as squats, lunges and leg lifts will all help you to strengthen your legs if you have been feeling heaviness. Hold onto something as you are doing these exercises at first and you will gradually build up the strength and balance.
MS can damage the nerves that affect your muscles. This can cause acute or paroxysmal pain in the form of spasms. Your arms and legs might shoot out uncontrollably and might have pain like cramping or pulling. Nerve pain can also be chronic in the form of painful or unusual sensations on your skin.
High doses of other vitamins can antagonize your immune-modulating, immunosuppressive therapies used to manage MS. Supplements that stimulate the immune system should be avoided in high doses. Those include selenium, zinc, B1, B2, folic acid, B6, vitamin A, biotin, magnesium, copper, and manganese.
You might take a pain reliever like acetaminophen or use a skin gel with a pain reliever like lidocaine. Your doctor could prescribe medications for seizures or depression. They affect how your central nervous system reacts to pain. You can also try warm compresses or pressure gloves.
Treatment with the cannabis oral spray nabiximols helped to relieve spasticity — increased muscle stiffness and spasms common in people with multiple sclerosis (MS) — among participants in two MS clinical trials, according to the results of a new analysis.
No muscle relaxers are available over the counter in the U.S., but some OTC medications can have muscle-relaxing effects. These include guaifenesin and NSAIDs like ibuprofen and naproxen.
For this type of weakness, progressive resistive exercise with weights can be very effective. A physical therapist can recommend a weight-training program that fits abilities. Damage to the nerve fibers (demyelination) in the spinal cord and brain that stimulate the muscles can also cause weakness.
When you have MS and you exercise, it can improve your fitness, endurance, and strength in your arms and legs. Studies have shown that this can also give you better control over your bowel and bladder function, and decreased overall fatigue. And it can give your mood a boost.
Research has shown that maintaining enough vitamin D in the body may lower the risk of multiple sclerosis (MS). Several studies have shown that people who get more sun exposure and vitamin D in their diets are less likely to have MS .
A cup of soothing green tea may help. A small study found that some of its compounds, including one called EGCG, may help ease these symptoms. People saw results after they drank green tea every day for at least 3 months.
Dr. Cross notes that these drugs include the anticonvulsants Neurontin (gabapentin), Tegretol (carbamazepine), and Dilantin (phenytoin), as well as the tricyclic antidepressant amitriptyline. For spasticity, the drugs baclofen and Zanaflex (tizanidine) can greatly reduce painful cramping and other symptoms.
According to Harvard Health Publishing, an anti-inflammatory diet should include foods like tomatoes, leafy greens such as spinach and kale, and fruits like strawberries, blueberries, cherries, and oranges. There's some evidence that consuming these foods could be beneficial for MS.