Several drug classes can cause or worsen lymphedema (swelling from fluid buildup in tissues) by causing fluid retention or affecting the lymphatic system, including calcium channel blockers, corticosteroids, NSAIDs, certain antidepressants, diabetes drugs (like thiazolidinediones), anticonvulsants (gabapentin, pregabalin), some hormones (tamoxifen), and chemotherapy agents (docetaxel), often by interfering with fluid balance or damaging lymphatic vessels.
The most commonly used drugs which can cause edema are: • calcium channel blockers e.g. amlodipine • nonsteroidal anti-inflammatory drugs (NSAIDs) e.g. ibuprofen • corticosteroids e.g. prednisolone • hormones and related compounds e.g. tamoxifen Calcium channel blockers (CCBs) These are probably the medications most ...
Discomfort can be an early sign of lymphoedema. You may have the following in the arm, breast or chest area: A dull ache. Heaviness.
Some of these are:
Puffy hand syndrome is a rare manifestation due to continuous intravenous drug abuse. It is a form of lymphedema caused by the sclerosing nature of intravenously administered drugs. It typically presents with bilateral, non-pitting edema at the dorsum of the hands.
This can happen after certain surgeries or because you have certain medical conditions or genetic conditions. You may develop lymphedema spontaneously, meaning it happens for no known reason. Lymphedema symptoms may be mild, causing minor swelling and discomfort.
Medicines that can cause fluid retention
Which medications are most likely to cause foot swelling? Drugs that commonly cause fluid retention include calcium channel blockers, steroids, and NSAIDs. Swelling in the lower extremities is a well-known side effect.
Drugs like Amlodipine, used for treating high blood pressure (hypertension) can promote lymphoedema. 4. Do you have scars from burns, radiation, or injuries, or have you had surgery in the abdomen, pelvic area or in the legs?
Yes, underwire bras can contribute to swollen lymph nodes by placing chronic pressure on key drainage points under the arm and breast. While not proven to cause cancer, they may restrict lymph flow, raising questions worth exploring if you've found a lump or feel persistent swelling.
An infection, such as cellulitis, can sometimes cause lymphoedema. Severe cellulitis can damage the tissue around the lymphatic system, causing it to become scarred. Filariasis can also cause lymphoedema. Lymphatic filariasis is a parasitic disease caused by microscopic, thread-like worms.
an aching, heavy feeling. difficulty with movement. repeated skin infections. developing hard, tight or thickened skin.
Certain medicines can cause swollen lymph nodes, including: Seizure medicines, such as phenytoin. Typhoid immunization.
Medication foot swelling is a common side effect of several prescriptions, which are as follows:
Lymphedema is swelling that can occur after cancer treatment, particularly when lymph nodes have been removed or treated with radiation. Risk increases with lymph node surgery or radiation, infections or injuries, excess body weight, and lack of movement.
In addition, venous stasis of the lower extremities (i.e., poor circulation because of varicose veins) caused by prolonged periods of sitting or sleeping with the legs down predisposes homeless people to dependent edema (swelling of the feet and legs), cellulitis, and skin ulcerations.
However, elderly patients are more likely to have unwanted effects (eg, problems with balance or walking, swelling in the feet or legs) and age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving gabapentin.
Tramadol is a potent painkiller used to treat high-intensity pain, but these painkillers cause an increase in fluid retention, thus increasing the accumulation of extracellular fluid and lowering sodium levels in the body.
Put your legs on pillows to raise them above your heart while lying down. Exercise your legs. This helps pump fluid from your legs back to your heart. Follow a low-salt diet, which may reduce fluid buildup and swelling.
Edema is a common sign of kidney disease. Since your kidneys are too damaged to remove all the sodium and water that they need to remove from your blood, they build up in your blood vessels and cause your capillaries to leak fluid into your tissues. Edema caused by CKD usually occurs in your legs and around your eyes.
Amlodipine
Amlodipine is a calcium channel blocker that's prescribed for high blood pressure and chest pain. One of the most common amlodipine side effects is swelling in the legs. And this may be more likely if you're taking a higher dosage (such as 10 mg daily) compared to a lower dosage.
Which Medications Cause the Most Weight Gain?
Self-care options for fluid retention