Peripheral neuropathy is the most common presentation of vitamin B12 deficiency. Depending upon the type of nerve involved, it may present as pain, numbness, tingling, loss of sensation, decreased motor activity, or decreased muscle mass.
Once you begin treating your vitamin B12 deficiency, it can take up to six to 12 months to fully recover. It is also common to not experience any improvement during the first few months of treatment. If you can, it's a good idea to address what's causing the deficiency.
The common signs of vitamin B12 are strange sensations in the body which often seem like numbness or tingling sensation in feet and limbs. The person may feel weak all the time; there will be physical exhaustion due to fatigue and mental exhaustion due to difficulty in thinking and reasoning.
B12 deficiency may cause demyelination of nerves in the peripheral and central nervous system13 and has been associated with peripheral neuropathy, loss of sensation in peripheral nerves, and weakness in lower extremities in older adults1, 14–16.
Vitamin B12, or cobalamin, is naturally found in animal foods. It can also be added to foods or supplements. Vitamin B12 is needed to form red blood cells and DNA. It is also a key player in the function and development of brain and nerve cells.
In many cases, supplementing with vitamin B-12 can reduce the pain associated with neuropathy. More rarely, it can help repair the myelin sheath, depending on the cause of the neuropathy. However, B-12's ability to speed up tissue regeneration and improve nerve function can be helpful for some.
Neurological symptoms of vitamin B12 deficiency can include:
Numbness or tingling in your hands and feet. Vision problems. Having a hard time remembering things or getting confused easily. Having a difficult time walking or speaking like you usually do.
A vitamin B12 deficiency can cause megaloblastic anemia. Megaloblasts are immature red blood cells that are larger than normal. They usually have an odd shape, too. When you have anemia, your red blood cells have trouble getting oxygen to your tissues and organs.
The NHS notes that vitamin B12 deficiency can cause “loss of physical coordination (ataxia), which can affect your whole body and cause difficulty speaking or walking”. The Mayo Clinic describes the walking style saying a person with vitamin B12 deficiency can walk unsteadily, or with their feet set wide apart.
There are certain foods that also need a cut-down in case of vitamin B12 deficiency. “Some foods and drinks can interfere with vitamin B complex intake like alcohol, caffeine and processed foods, etc should be avoided completely,” Shah added.
Stage 1 is decreased levels of vitamin B12 in the blood. Stage 2 is low concentration of vitamin B12 in the cell and metabolic abnormalities. Stage 3 is increased levels of homocysteine and MMA and decreased DNA synthesis resulting in neuropsychiatric symptoms. Stage 4 is macrocytic anemia.
Pernicious anaemia causes your immune system to attack the cells in your stomach that produce the intrinsic factor, which means your body is unable to absorb vitamin B12.
It may take a few weeks before your vitamin B12 levels and symptoms (such as extreme tiredness or lack of energy) start to improve. If you have hydroxocobalamin injections to boost your vitamin B12 levels at the start of treatment, the cyanocobalamin tablets may start to work within a few days.
B vitamins are known for their ability to support healthy nervous system function. Vitamins B-1, B-6, and B-12 have been found to be especially beneficial for treating neuropathy. Vitamin B-1, also known as thiamine, helps to reduce pain and inflammation and vitamin B-6 preserves the covering on nerve endings.
Inadequate dietary intake
A balanced diet typically provides sufficient vitamin B12; however, strict vegans and people with a poor diet are at higher risk of developing a deficiency. Good sources of vitamin B12 include: Meat. Fish.
Disturbed or blurred vision can also occur as a result of a Vitamin B12 deficiency. This happens when the deficiency causes damage to the optic nerve that leads to your eyes. The nervous signal that travels from the eye to the brain is disturbed due to this damage, leading to impaired vision.
Bananas are a cheap, healthy, and nutrient-dense fruit that can easily become a part of every individual's diet. It is one of the best fruits rich in vitamin B12.
Magnesium is one of the most essential nutrients in the human body. It plays a vital role in nerve regeneration and functional recovery by reducing the inflammation and causing Schwann cell proliferation at the injury site, which increases axonal recovery.
Take 1000-5000mcg daily of the active forms of B12 (methyl-cobalamin and adenysl-cobalamin) for 1 month and then re-assess symptoms. Vitamin B9 (folate) and vitamin B6 work together with B12, supplementing these at the same time often gives better results.
Vitamin deficiencies are a common cause of paresthesias. The B vitamins — vitamin B12 and vitamin B6 — are the most common ones. Deficiencies in copper, calcium, and magnesium can also lead to tingling in your hands and feet. Most of the time, correcting the deficiency can help reverse the symptoms.
Conditions affecting the stomach
Some stomach conditions or stomach operations can prevent the absorption of enough vitamin B12. For example, a gastrectomy, a surgical procedure where part of your stomach is removed, increases your risk of developing a vitamin B12 deficiency.