Schizophrenia is more likely to respond and have a good outcome with early diagnosis and treatment. Avoid alcohol and recreational drug use. Alcohol and drug use can make schizophrenia symptoms worse and can lead to other issues. This includes using prescription medications in a way other than prescribed.
Certain drugs, particularly cannabis, cocaine, LSD or amphetamines, may trigger symptoms of schizophrenia in people who are susceptible. Using amphetamines or cocaine can lead to psychosis, and can cause a relapse in people recovering from an earlier episode.
Schizophrenia is a chronic disorder that may wax and wane in severity, but it does not typically worsen with age. 1 For some people, the symptoms of schizophrenia will improve over time while for others the symptoms will stay the same or get worse.
Factors for poor prognosis
Early-onset of illness. Male. Strong negative symptoms. Family history of schizophrenia.
For people living with schizophrenia stress has a special significance because excessive stress is often a cause of a relapse of the psychotic symptoms and so they must be very careful to manage and monitor the stress in their lives.
Not taking medication regularly or as prescribed is by far the most common cause of schizophrenia relapse. Persistent use of drugs or alcohol and criticism from caregivers are next on the list. "Many people with schizophrenia abuse some type of drug, most commonly marijuana," Frangou says.
The last stage is the residual phase of schizophrenia. In this phase, you're starting to recover, but still have some symptoms.
The peak age of onset of schizophrenia is 15 – 25 years in men and 20 – 30 years in women. It is often preceded by a prodromal phase of vague symptoms, some odd behaviours and a decline in functioning at school or work and interpersonally.
For example, the person may neglect personal hygiene or appear to lack emotion (doesn't make eye contact, doesn't change facial expressions or speaks in a monotone). Also, the person may lose interest in everyday activities, socially withdraw or lack the ability to experience pleasure.
People with schizophrenia experience psychosis, which means they can have serious problems with thinking clearly, emotions, and knowing what is real and what is not. This can include hearing or seeing things that are not there (hallucinations), and having very strange beliefs that are abnormal or not true (delusions).
In most people with schizophrenia, symptoms generally start in the mid- to late 20s, though it can start later, up to the mid-30s. Schizophrenia is considered early onset when it starts before the age of 18. Onset of schizophrenia in children younger than age 13 is extremely rare.
A schizophrenic episode can last days or weeks, and in rare cases, months, says Dr. D'Souza. Some people may experience only one or two schizophrenic episodes in their lifetime, whereas for others the episodes may come and go in phases.
Using drugs, such as marijuana, cocaine and amphetamines, can also exacerbate schizophrenic symptoms and worsen their severity. Schizophrenia is often mistaken for substance abuse because the disorders have similar symptoms. This can sometimes make it difficult to diagnose schizophrenia or co-occurring disorders.
Avoid using marijuana, alcohol, nicotine, cocaine or other stimulants, and street drugs. They can keep antipsychotic drugs from working well. They can also cause paranoia or make it worse. You might have to take different kinds of drugs for other symptoms, too.
Avoiding drugs and alcohol
Alcohol can cause depression and psychosis, while illegal drugs may make your schizophrenia worse. Drugs and alcohol can also react badly with antipsychotic medicines. If you're currently using drugs or alcohol and finding it hard to stop, ask your care co-ordinator or GP for help.
Past studies have reported that offspring of affected mothers have a higher risk of schizophrenia than the offspring of affected fathers; however, other studies found no such maternal effect [Gottesman and Shields, 1976].
Schizophrenia does not have a sudden onset—meaning a person does not wake up one day with schizophrenia. Instead, the illness usually develops slowly over months or years and often comes with warning signs.
Schizophrenia affects men and women equally. It occurs at similar rates in all ethnic groups around the world. Symptoms such as hallucinations and delusions usually start between ages 16 and 30. Men tend to experience symptoms earlier than women.
The symptoms of schizophrenia are usually classified into: positive symptoms – any change in behaviour or thoughts, such as hallucinations or delusions. negative symptoms – where people appear to withdraw from the world around then, take no interest in everyday social interactions, and often appear emotionless and flat.
When people with schizophrenia live without adequate treatment, their mental health can worsen. Not only can the signs of schizophrenia get more severe, but they can also develop other mental health disorders, including: Obsessive-Compulsive Disorder (OCD) Anxiety Disorders.
Haloperidol, fluphenazine, and chlorpromazine are known as conventional, or typical, antipsychotics and have been used to treat schizophrenia for years.
Decreased brain levels of vitamin B12 have also been reported in schizophrenia[59]. Deficiencies in vitamin D have also been implicated in schizophrenia, and developmental deficiency of D3 has been associated with an increased risk of developing schizophrenia in adulthood[13,60,61].