If you take more than your prescribed dose of diazepam you may get symptoms including: poor co-ordination or trouble speaking. feeling sleepy. a slow or irregular heartbeat.
drowsy or sedating antihistamines, such as chlorphenamine or promethazine. strong painkillers, such as codeine, methadone, morphine, oxycodone, pethidine or tramadol. HIV medicines, such as ritonavir, atazanavir, efavirenz or saquinavir. antifungal medicines, such as fluconazole.
Diazepam is used to treat anxiety, alcohol withdrawal, and seizures. It is also used to relieve muscle spasms and to provide sedation before medical procedures. This medication works by calming the brain and nerves. Diazepam belongs to a class of drugs known as benzodiazepines.
Long-term use of the drug can cause irreversible damage to a person's cardiovascular system, liver, and even brain. Additionally, as levels of the drug increase over time, Valium abuse can have serious effects on a person's cognition, judgment, and memory.
There is evidence use of these drugs stops the normal adjustment response that would gradually lessen anxiety over time, and may increase anxiety in the long term, especially if used repeatedly. Diazepam and similar controlled drugs are illegal in a number of countriesi.
Long-term use of diazepam can lead to chemical dependency and, eventually, to severe addiction. Understanding the health complications of Valium addiction may encourage nonmedical users of this drug to reach out for help.
Adults—2 to 10 milligrams (mg) 2 to 4 times a day. Older adults—At first, 2 to 2.5 mg 1 or 2 times a day. Your doctor may increase your dose if needed. Children 6 months of age and older—At first, 1 to 2.5 mg 3 or 4 times per day.
People are not normally prescribed diazepam for more than four weeks as people can become dependent on it if they take it for longer. They may also get withdrawal symptoms when they stop taking it. You and your doctor should talk about how long you might need to take diazepam.
Risk of dependence: Using diazepam, even as prescribed, can lead to physical dependence and withdrawal if you stop taking the drug suddenly. Withdrawal can be life threatening. Misuse or addiction: Taking this drug can also lead to misuse and addiction.
Diazepam has an average rating of 8.5 out of 10 from a total of 805 reviews on Drugs.com. 82% of reviewers reported a positive experience, while 9% reported a negative experience.
Conclusions: In healthy subjects, diazepam taken as a hypnotic agent induces a significant HR increase, possibly mediated by a decrease in vagal tone. This effect might be of clinical relevance due to the role that HR plays as an independent cardiovascular risk factor.
Doctors generally recommend the drug should be used at dosages of 2-10 mg. This amount can be taken up to four times in a 24-hour time frame. The maximum daily total use in milligrams should not exceed 40 mg.
Diazepam is used to treat anxiety that is more serious than that caused by the normal stress of everyday life. Diazepam is also used to relax muscles and treat muscle spasms that occur due to injury and conditions like cerebral palsy and paraplegia.
Diazepam is a benzodiazepine sleeping pill. It is also known by the trade names Dialar, Diazemuls, Diazepam Desitin, Diazepam Rectubes, Stesolid and Tensium.
It is concluded that patients receiving a 2.5 mg dose of lorazepam should not drive or operate machinery for 24 h after the administration. After diazepam (10 mg) or medazepam (15 mg) patients should refrain from driving or participating inskilled performances for only 5 to 7 hours.
When administered intravenously, diazepam has an onset of action within 1 to 3 minutes, while oral dosing onset ranges between 15 to 60 minutes. In addition, diazepam is long-lasting, with a duration of action of more than 12 hours.
Diazepam 5 MG Tablet is an anticonvulsant and belongs to a group of drugs called benzodiazepine. It is used to treat anxiety disorders, alcohol withdrawal symptoms and muscle spasms. It is sometimes used in combination with other medications to treat seizures. It also provides sedation before medical procedures.
The long-term use of BDZ is associated with the accumulation of generalized cognitive deficits that lead to an increased risk of dementia in long-term BDZ users compared to short-term BDZ users.
Diazepam therapy has not been associated with serum aminotransferase elevations, and clinically apparent liver injury from diazepam has been reported, but is exceedingly rare.
This medicine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed.
Bottom Line. Diazepam may be used occasionally to relieve anxiety and prolonged seizures; however, it is addictive and withdrawal symptoms can be severe.
In double-blind sequential study, diazepam was compared with the proven antidepressant moclobemide, in patients with atypical depression. Both agents significantly improved depression ratings over eight weeks of treatment.
“You shouldn't drink alcohol while taking diazepam,” warns Medical News Today. “This drug can interfere with your judgment, thinking, and motor skills. It can also make you drowsy and cause your breathing to slow down or stop.