Statins help lower low-density lipoprotein (LDL) cholesterol, also known as “bad” cholesterol, in the blood. They draw cholesterol out of plaque and stabilize plaque, Blaha says.
Conversely, pathological studies have documented statin-induced changes in plaque composition as early as 3 months after therapy initiation.
You can “unclog” your arteries with natural methods, including diet, exercise, and stress management. Quitting smoking, if you smoke, can also help reverse plaque.
A: Yes. There have been several clinical studies — many of them done here at Cleveland Clinic — that show statins can reverse plaque buildup. Two statins in particular, atorvastatin, which is sold under the brand name Lipitor, and rosuvastatin, which is sold under the brand name Crestor, are the strongest statins.
Abstract. Previous studies have shown that the commonly used statin lipid lowering drugs can delay the progression of atherosclerotic plaque. Atorvastatin can stabilize atherosclerotic plaque, but it can not reverse atheromatous plaque.
The American College of Cardiology and American Heart Association developed some prescription guidelines. Typically, if a person's LDL cholesterol (bad cholesterol) is 190 or higher, they're often advised to start a statin.
Blocked arteries caused by plaque buildup and blood clots are the leading cause of death in the U.S. Reducing cholesterol and other risk factors can help prevent cholesterol plaques from forming. Occasionally, it can even reverse some plaque buildup.
In vitro (15–19) and animal (19–23) studies suggest biological mechanisms through which magnesium may prevent or reverse plaque formation and calcification.
While some studies suggest statins may reduce plaque volume, the reduction is small even with the use of high-dose statins. Due to this small change in plaque volume, other effects of statin therapy on plaques have been proposed.
A person's arteries can become clogged when plaques build up inside them, reducing blood flow. Eating specific foods cannot cleanse plaques out of the arteries, but a healthful diet can help manage and prevent heart disease. Over time, plaque buildup can lead to thickened or hardened arteries.
If you're taking a statin medication to lower your cholesterol, you will need to keep taking your prescription, or your cholesterol will likely go back up. Stopping your statin can put you at risk of having heart disease and other preventable health problems like stroke and heart attack from high cholesterol.
inflammation of the liver (hepatitis), which can cause flu-like symptoms. inflammation of the pancreas (pancreatitis), which can cause stomach pain. skin problems, such as acne or an itchy red rash. sexual problems, such as loss of libido (reduced sex drive) or erectile dysfunction.
Low-density lipoprotein (LDL) cholesterol.
The most important thing your doctor will keep in mind when thinking about statin treatment is your long-term risk of a heart attack or stroke. If your risk is very low, you probably won't need a statin, unless your LDL is above 190 mg/dL (4.92 mmol/L).
A healthy diet rich in nutrient-dense foods may help reduce your risk of developing clogged arteries. Research has shown that adding foods like cruciferous vegetables, fish, berries, olive oil, oats, onions, greens, and beans to your diet may be an effective way to prevent atherosclerosis.
Plaque build-up in arteries is, unfortunately, a natural part of living. Even children and adolescents have early evidence of the process. However, diet and other lifestyle factors play an important role. High blood pressure, high LDL cholesterol and smoking can all worsen atherosclerosis.
Vitamin K-2 acts to prevent calcification of arteries, and it can reverse calcification after it happens. Secondly, Vitamin K-2 also uniquely activates a hormone in our bones named osteocalcin. This activation step is necessary and essential for the transfer of circulating calcium out of plasma into the bone matrix.
In summary, fish oil may reduce atherosclerosis by activating numerous nuclear receptors including PPAR-alpha and PPAR-gamma, by inhibiting the infiltration of macrophages and as the release of MMPs, and by preventing the weakening and rupturing of atherosclerotic plaque.
Coronary atherosclerotic plaques associated with increasing exercise volume may also be more stable and less likely to rupture. We found that the most active athletes had fewer mixed plaques and more often only calcified plaques,4,5 which are associated with a lower risk of cardiovascular events.
Through angioplasty, our cardiologists are able to treat patients with blocked or clogged coronary arteries quickly without surgery. During the procedure, a cardiologist threads a balloon-tipped catheter to the site of the narrowed or blocked artery and then inflates the balloon to open the vessel.
Toxicity to body
Some participants stated that they perceived statins as 'a load of trash' that could potentially cause harmful long-term effects on the body. As a result, they preferred or opted for what they considered to be alternatives to statins, including dietary and other lifestyle changes.
Statins should not be taken if you have liver disease or if blood tests suggest that your liver may not be working properly. This is because statins can affect your liver, and this is more likely to cause serious problems if you already have a damaged liver.