You can't fully reverse plaque buildup in arteries, but aggressive lifestyle changes and medications, especially statins, can significantly slow its growth, stabilize it, and even reduce its size, preventing heart attacks and strokes. The key is managing risk factors like high cholesterol, blood pressure, and diabetes through a heart-healthy diet, regular exercise, quitting smoking, and stress management, working with your doctor for a comprehensive plan.
The bottom line: While atherosclerosis may not be fully reversible, proactive lifestyle changes and dietary modifications can effectively manage coronary artery disease — reducing the risk of further plaque deposition and promoting overall heart health.
If atherosclerosis is in the arteries leading to your brain, you may feel symptoms of atherosclerosis that are similar to stroke, such as a sudden numbness or weakness in your arms or legs; difficulty speaking or slurred speech; sudden changes in eyesight, dizziness, sudden and severe headache; or drooping muscles in ...
Although fully hardened plaque won't go away without dental intervention, it's possible to manage plaque as it builds up, before it hardens, and it's also possible to prevent plaque buildup from happening at all. If you notice that your teeth feel fuzzy when you run your tongue across them, you're noticing plaque.
When your heart pumps faster during aerobic exercise, it pushes more blood through the arteries. This keeps the arteries wider and more flexible, reducing blood pressure and making arteries less likely to collect plaque. Examples of aerobic exercise include walking, running, dancing, rowing, and swimming.
High blood pressure and high cholesterol
Cholesterol is the main component in plaque. Your liver naturally produces all the cholesterol you need, but you may consume extra cholesterol in the food you eat. As cholesterol increases in your blood, it can form fatty deposits (plaque) in your arteries.
Chest pain, or angina, is one of the most common early signs of a blocked artery. It's also one of the most well-known symptoms of a heart attack, which can make it difficult to know if chest pain is an emergency.
After 45, men may have a lot of plaque buildup. Signs of atherosclerosis in women are likely to appear after age 55. Plaque is dangerous because it can break off and form a clot that blocks your artery and stops blood flow to your heart, brain, or legs. That might cause a heart attack, stroke, or gangrene.
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Heart-healthy living, along with ongoing medical care, can help prevent complications of atherosclerosis and help you have a long, healthy life. Plaque buildup can take away years of life, especially for people who have complications.
Although you cannot reverse damage to a heart valve, you can slow AS by managing other heart conditions and risks. For instance, your doctor can prescribe medications to lower blood pressure and cholesterol, regulate abnormal heart rhythms or relieve fluid buildup.
Symptoms of Calcium Build-Up
They're caused by high cholesterol, smoking, genetics, and a diet high in unhealthy fats. Symptoms of clogged arteries can include fatigue, shortness of breath, dizziness, and chest pain.
Some of the best evidence that coronary artery disease is reversible comes from autopsies performed on people who lived through prolonged periods of starvation during World War II. Their coronary arteries showed little or no atherosclerosis.
Many medicines are available to treat coronary artery disease, including: Cholesterol medicine. Your healthcare professional might recommend this type of medicine to lower "bad" LDL cholesterol and reduce plaque buildup in the arteries. Such medicines include statins, niacin, fibrates and bile acid sequestrants.
For most Americans over the age of 60, atherosclerosis is a common fact of life, viewed as an inevitable consequence of growing old. Atherosclerosis is a disease in which plaque, composed of fat, cholesterol, calcium and other substances, builds up inside the arteries.
McMaster-led study shows hidden fat contributes to artery damage, regardless of body weight. Hamilton, ON — October 17, 2025) — A new study led by researchers at McMaster University reveals that hidden fat deep inside the abdomen and liver may quietly damage arteries, even in people who appear healthy.
Colchicine acts on many anti-inflammatory pathways, which translates to cardiovascular event reduction, plaque transformation, and plaque reduction. With the FDA's 2023 approval of colchicine for reducing cardiovascular events, a novel clinical pathway opens.
While you can't confirm a blockage yourself, these steps can help you stay proactive:
Coronary arteries with severe blockages, up to 99%, can often be treated with traditional stenting procedure. Once an artery becomes 100% blocked, it is considered a coronary chronic total occlusion, or CTO. Specialized equipment, techniques and physician training are required to open the artery with a stent.
It may seem counterintuitive, but it is entirely possible to have normal blood pressure while still having clogged arteries.
Unfortunately, as we age, plaque accumulates in our arteries. This starts as soft, cholesterol-laden plaque that eventually calcifies and hardens. Even though the process effectively begins at birth, most people do not have clinically significant blockages in their arteries until they are well into middle age.
Stress doesn't just make you feel tense – it also causes inflammation. This can lead to plaque buildup in your arteries and increase your risk of heart disease. “Inflammation is one of the key drivers of plaque buildup in arteries, which can eventually lead to blockages,” says Dr. Jaiswal.
While some studies suggest statins may reduce plaque volume, the reduction is small even with the use of high-dose statins. Due to this small change in plaque volume, other effects of statin therapy on plaques have been proposed.