Acute leukemias — which are incredibly rare — are the most rapidly progressing cancer we know of. The white cells in the blood grow very quickly, over a matter of days to weeks. Sometimes a patient with acute leukemia has no symptoms or has normal blood work even a few weeks or months before the diagnosis.
In some cases, your doctor might order bone marrow testing even though your blood tests didn't indicate leukemia. That's because in some types of leukemia, cancer cells stay in the bone marrow and don't circulate in the blood.
If you have leukemia, your blood cells count will likely show higher than usual levels of white blood cells, which include leukemic cells. You may also have lower than usual red blood cell and platelet cell counts. If all three types are low, this is known as pancytopenia.
A complete blood count (CBC) is a common blood test that your doctor may recommend to: Help diagnose some blood cancers, such as leukemia and lymphoma. Find out if cancer has spread to the bone marrow. See how a person's body is handling cancer treatment.
Aside from leukemia, most cancers cannot be detected in routine blood work, such as a CBC test. However, specific blood tests are designed to identify tumor markers, which are chemicals and proteins that may be found in the blood in higher quantities than normal when cancer is present.
Early Symptoms of Acute Leukemia
Shortness of breath. Fatigue. Unexplained fever. Night sweats.
Many types of leukemia produce no obvious symptoms in the early stages. Eventually, symptoms may include any of the following: Anemia and related symptoms, such as fatigue, pallor, and a general feeling of illness.
People often feel ill quite quickly. Most symptoms of acute leukaemia are caused by leukaemia cells filling the bone marrow. This means healthy blood cells do not move into the blood as normal.
Because many types of leukemia show no obvious symptoms early in the disease, leukemia may be diagnosed incidentally during a physical exam or as a result of routine blood testing.
The median age of a patient diagnosed with acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL) or chronic myeloid leukemia (CML) is 65 years and older. However, most cases of acute lymphocytic leukemia (ALL) occur in people under 20 years old. The median age of an ALL patient at diagnosis is 15.
By looking at a sample of your blood, your doctor can determine if you have abnormal levels of red or white blood cells or platelets — which may suggest leukemia. A blood test may also show the presence of leukemia cells, though not all types of leukemia cause the leukemia cells to circulate in the blood.
Leukemia or myelodysplastic syndromes (MDS) can cause bone or joint pain, usually because your bone marrow has become overcrowded with cancer cells. At times, these cells may form a mass near the spinal cord's nerves or in the joints.
What is Leukemia (Blood Cancer)? Leukemia starts in the soft, inner part of the bones (bone marrow), but often moves quickly into the blood. It can then spread to other parts of the body, such as the lymph nodes, spleen, liver, central nervous system and other organs.
Chronic leukemia often causes only a few symptoms or none at all. Signs and symptoms usually develop gradually. People with a chronic leukemia often complain that they just do not feel well.
Some symptoms, like night sweats, fever, fatigue and achiness, resemble flu-like symptoms. Unlike symptoms of the flu, which generally subside as you get better, leukemia symptoms generally last longer than two weeks, and may include sudden weight loss, bone and joint pain and easy bleeding or bruising.
In CLL, the leukemia cells grow out of control and crowd out normal blood cells. These cells often build up slowly over time. Many people don't have any symptoms for at least a few years. In time, the cells can spread to other parts of the body, including the lymph nodes, liver, and spleen.
While the exact cause of leukemia—or any cancer, for that matter—is unknown, there are several risk factors that have been identified, such as radiation exposure, previous cancer treatment and being over the age of 65.
Spotting bone and joint pain
Bone pain caused by leukaemia is most commonly felt in the long bones of the arms and legs, or in the ribs and sternum of the rib cage.
They occur in unusual places – In cases of leukaemia, quite often bruises will appear in places that you wouldn't normally expect, especially; the back, legs, and hands.
Bone pain can occur in leukemia patients when the bone marrow expands from the accumulation of abnormal white blood cells and may manifest as a sharp pain or a dull pain, depending on the location. The long bones of the legs and arms are the most common location to experience this pain.
Chronic leukemia usually gets worse slowly, over months to years, while acute leukemia develops quickly and progresses over days to weeks. The two main types of leukemia can be further organized into groups that are based on the type of white blood cell that is affected — lymphoid or myeloid.
Age – Generally speaking, individuals over the age of 65 are more at risk for leukemia. Demographics – While anyone can conceivably develop leukemia, white males are statistically most susceptible. Radiation exposure – Exposure to radiation from an atomic bomb increases the likelihood that leukemia cells will form.
The onset of leukemia can be acute (sudden onset) or chronic (slow onset). In acute leukemia, cancer cells multiply quickly. In chronic leukemia, the disease progresses slowly and early symptoms may be very mild.
If caught early, leukemia can be cured by undergoing several cancer treatments.