MS is usually diagnosed between the ages of 20 and 50, but it can go undetected for years. In fact, a 2021 study suggested that many people with MS experience disease symptoms several years before being officially diagnosed with the disease.
Multiple sclerosis (MS) is a condition that can affect the brain and spinal cord, causing a wide range of potential symptoms, including problems with vision, arm or leg movement, sensation or balance. It's a lifelong condition that can sometimes cause serious disability, although it can occasionally be mild.
Those symptoms include loss of vision in an eye, loss of power in an arm or leg or a rising sense of numbness in the legs. Other common symptoms associated with MS include spasms, fatigue, depression, incontinence issues, sexual dysfunction, and walking difficulties.
Cognition tests showed only mild impairment in three patients. Researchers said the study suggests that “it is not uncommon for people with relapsing MS “to have only mild or no physical or cognitive dysfunction approximately three decades after clinical onset.” MS may have a bimodal progression, the team said.
People should consider the diagnosis of MS if they have one or more of these symptoms: vision loss in one or both eyes. acute paralysis in the legs or along one side of the body. acute numbness and tingling in a limb.
Sjogren's syndrome is an autoimmune disease that can mimic some of the symptoms of MS such as fatigue and joint pain.
While there is no definitive blood test for MS, blood tests can rule out other conditions that cause symptoms similar to those of MS, including lupus erythematosis, Sjogren's, vitamin and mineral deficiencies, some infections, and rare hereditary diseases.
Here's where MS (typically) starts
Optic neuritis, or inflammation of the optic nerve, is usually the most common, Shoemaker says. You may experience eye pain, blurred vision and headache. It often occurs on one side and can eventually lead to partial or total vision loss.
Early signs and symptoms of MS
tingling and numbness. pains and spasms. weakness or fatigue. balance problems or dizziness.
And if left untreated, MS can result in more nerve damage and an increase in symptoms. Starting treatment soon after you're diagnosed and sticking with it may also help delay the potential progression from relapsing-remitting MS (RRMS) to secondary-progressive MS (SPMS).
Although MRI is a very useful diagnostic tool, a normal MRI of the brain does not rule out the possibility of MS. About 5 percent of people who are confirmed to have MS do not initially have brain lesions evidenced by MRI.
MS causes the immune system to attack nerve fibers and causes miscommunication between the brain and other parts of the body. When your optometrist detects optic nerve inflammation, that can indicate a diagnosis of MS.
MRI scans are an important way to help health care providers figure out if a person has MS or not, but MRI scans cannot diagnose MS by themselves. While it is true that almost all people with MS will have lesions on MRI, not all people with MRI lesions have MS.
People with multiple sclerosis (MS) tend to have their first symptoms between the ages of 20 and 40. Usually the symptoms get better, but then they come back. Some come and go, while others linger. No two people have exactly the same symptoms.
People may experience blurred vision, double vision, eye pain or loss of color vision. Difficulty articulating words or swallowing and slurred speech may occur if there's damage to the area that controls the mouth and throat.
Cluster headaches have been linked to MS lesions in the brainstem, especially in the part where the trigeminal nerve originates. 7 This is the nerve involved with trigeminal neuralgia—one of the most painful MS symptoms.
Neurofilament light chain (NfL) is a new and easily accessible blood test that could predict disease progressions of several neurodegenerative diseases, such as multiple sclerosis (MS), Parkinson's disease, and Alzheimer's Disease, according to a recent press release by LabCorp.
A wide range of conditions can be mistaken for MS, including: migraine, cerebral small vessel disease, fibromyalgia, functional neurological disorders, and neuromyelitis optica spectrum disorders, along with uncommon inflammatory, infectious and metabolic conditions (1, 3).
Floaters are a common ocular symptom for individuals with multiple sclerosis, but MS isn't a leading cause. On their own, floaters don't usually indicate serious conditions. Eye conditions like optic neuritis can be an early warning sign of oncoming multiple sclerosis.
A common visual symptom of MS is optic neuritis — inflammation of the optic (vision) nerve. Optic neuritis usually occurs in one eye and may cause aching pain with eye movement, blurred vision, dim vision, or loss of color vision. For example, the color red may appear washed out or gray.
Multiple sclerosis (MS).
This demyelinating disease can lead to severe dry eye. In MS, poor corneal sensory impulse conduction can result in insufficient tear production, and lagophthalmos-associated DED can occur due to poor motor control.