report on the correlation between dietary magnesium intake and kidney function decline from a large epidemiological investigation, the HANDLS study. Compared with the upper tertile of dietary magnesium intake, the risk for rapid kidney function decline was roughly doubled in the lower tertile.
Safety of Supplementing with Magnesium for Kidneys
“Because the kidneys are responsible for the excretion of magnesium, as kidney function declines this can mean that magnesium levels may become too high. This typically doesn't become a problem until people are in stage 4 to 5 CKD.
Magnesium deficiency is known to be associated with hypertension, insulin resistance, and endothelial dysfunction, common risk factors that contribute to the progression of CKD. Lower serum magnesium levels are associated with an increased risk of both incident CKD and progression to end-stage kidney disease.
However, because of the renal excretion of Mg, there is a risk that Mg therapy might result in toxic hypermagnesemia in patients with reduced kidney function.
Magnesium supplementation can not only preserve liver function, but also slow the progression of liver disease, and reduce the mortality associated.
However, by taking supplements, most people get more magnesium than necessary. To avoid an overdose, do not take more than 350 mg of magnesium a day.
The kidney has a vital role in magnesium homeostasis: regulation of magnesium excretion is determined by filtration and reabsorption. In individuals with normal renal function, ∼74–100 mmol (1800–2400 mg) of magnesium are filtered everyday [2, 3] (see also Baaji et al.
People with diabetes, intestinal disease, heart disease or kidney disease should not take magnesium before speaking with their health care provider. Overdose. Signs of a magnesium overdose can include nausea, diarrhea, low blood pressure, muscle weakness, and fatigue. At very high doses, magnesium can be fatal.
You may need to avoid some vitamins and minerals if you have kidney disease. Some of these include vitamins A, E and K. These vitamins are more likely to build up in your body and can cause harm if you have too much.
High doses of magnesium from supplements or medications can cause nausea, abdominal cramping and diarrhea. In addition, the magnesium in supplements can interact with some types of antibiotics and other medicines.
Every organ in the body, especially the heart, muscles, and kidneys, needs the mineral magnesium. It also contributes to the makeup of teeth and bones. Magnesium is needed for many functions in the body. This includes the physical and chemical processes in the body that convert or use energy (metabolism).
Highest vs. lowest quartile of serum magnesium associated with a 58% increased CKD risk. Low serum magnesium levels are associated with an elevated the risk of developing kidney disease, according to a new study.
A few examples are St. Johns Wort, echinacea, ginkgo, garlic, ginseng, ginger, and blue cohosh. If you have a kidney transplant you are especially at risk, as any interaction between herbal supplements and medicines could put you at risk for losing your kidney.
Nassar says that taking a magnesium supplement every day likely isn't unsafe for most people. Just be sure you're not taking too much magnesium. The maximum dietary allowance for most adults is around 400 mg or less.
Taking magnesium with these medications might cause blood pressure to go too low. Some of these medications include nifedipine (Adalat, Procardia), verapamil (Calan, Isoptin, Verelan), diltiazem (Cardizem), isradipine (DynaCirc), felodipine (Plendil), amlodipine (Norvasc), and others.
Severe hypermagnesemia (levels greater than 12 mg/dL) can lead to cardiovascular complications (hypotension, and arrhythmias) and neurological disorder (confusion and lethargy). Higher values of serum magnesium (exceeding 15 mg/dL) can induce cardiorespiratory arrest and coma.
Magnesium is an inhibitor of calcium crystal growth and contributes to urinary calcium oxalate and calcium phosphate supersaturation.
Does Magnesium Make You Pee Frequently? In short, there is no link between magnesium and frequent urination. However, magnesium can help with water retention, so you may find that when you take magnesium, you pee more. Though, this is most likely due to it helping your body flush out extra water.
UL: The Tolerable Upper Intake Level is the maximum daily intake unlikely to cause harmful effects on health. The UL for magnesium is 350 milligrams from supplements only. High-dose supplements can lead to diarrhea, nausea, and cramping in some people.