Almost all people with ankylosing spondylitis can expect to lead normal and productive lives. Despite the chronic nature of the illness, only a few people with ankylosing spondylitis will become severely disabled.
Whether it's through physical therapy or on your own, dedicating time to stretching is key. “We recommend making sure that you maintain your flexibility,” says Dr. Elghawy. “And so doing with physical therapy or flexibility exercises on your own for your low back can provide a lot of relief.”
If you or a loved one is living with ankylosing spondylitis, you may wonder what you can do to relieve your symptoms and prevent disease progression, as well as what your rheumatologist can do. The good news is many people are able to reduce their pain and stiffness with medication, exercise, and a healthy diet.
Some people with AS are able to remain fully independent or minimally disabled in the long term. However, some people eventually become severely disabled as a result of the bones in their spine fusing in a fixed position and damage to other joints, such as the hips or knees.
Symptoms of ankylosing spondylitis vary from person to person. Some people have mild episodes of pain that come and go, while others will have chronic, severe pain. The symptoms of ankylosing spondylitis, whether mild or severe, may worsen in “flares” and improve during periods of remission.
This is the first phase of ankylosing spondylitis. It happens when nr-axSpA gradually gets worse and affects the sacroiliac joints and the bones of the spine. Your doctor will be able to see noticeable changes in these joints on an X-ray.
Almost all people with ankylosing spondylitis can expect to lead normal and productive lives. Despite the chronic nature of the illness, only a few people with ankylosing spondylitis will become severely disabled.
Dan Reynolds Has Ankylosing Spondylitis
Prior to learning of his AS, Reynolds was diagnosed with a type of inflammatory bowel disease called ulcerative colitis when he was 21. “That should have been an indication that I was prone to these autoimmune diseases,” Reynolds told Practical Pain Management magazine.
In some cases, ankylosing spondylitis can be debilitating and lead to disability, according to the SAA. Over time, the inflammation associated with ankylosing spondylitis can cause the vertebrae of the spine to fuse together. In severe cases, when this happens, the spine can curve and cause a stooped position.
This progression can take 10 years or more to happen. And not everyone with nr-axSpA will progress to AS. Another method of measuring progression is looking at inflammatory blood markers. Many people with active inflammatory axSpA have more signs of inflammation in their blood.
Don't do movements that cause pain
Carefully consider high-impact exercises, such as running, or jarring and twisting sports, such as tennis, squash, and racquetball. These could increase pain in the spine, hips, and knees.
Ankylosing spondylitis (AS) is a chronic, inflammatory disease of the axial spine that can manifest with various clinical signs and symptoms. Chronic back pain and progressive spinal stiffness are the most common features of the disease.
Ankylosing spondylitis is a chronic, inflammatory disorder and a rare form of arthritis. Triggers for ankylosing spondylitis include infections (gastrointestinal infections, urinary tract infections [UTIs], and respiratory infections), heavy physical activity, work stress, emotional stress, and pregnancy.
There's no cure for ankylosing spondylitis (AS), but treatment is available to help relieve the symptoms. Treatment can also help delay or prevent the process of the spine joining up (fusing) and stiffening. These treatments can also help if you have non-radiographic axial spondyloarthritis.
Say, “You know arthritis makes joints like the knees and wrists painful. Well, I have a kind of arthritis that affects the spine called ankylosing spondylitis.” You can also bring remind friends and family of the symptoms you've been having and connect them to your diagnosis.
There is no known specific cause. Ankylosing spondylitis is relatively rare, affecting about 1 in 1,000 people. It is believed that people with the gene called HLA-B27 are at the greatest increased risk for developing ankylosing spondylitis, not everyone with the gene develops the condition.
Can ankylosing spondylitis be inherited? AS can run in families, and the HLA-B27 gene variant can be inherited from another family member. If you have AS and tests show you carry the HLA-B27 gene variant then there is a 1 in 2 chance that you could pass on the gene variant to any children you have.
"B27 disease" is a new autoimmune disease that afflicts millions of people throughout the world. "B27 disease" occurs in individuals who have ankylosing spondylitis (AS) or preankylosing spondylitis and/or uveitis and are also positive for HLA-B27.
The most prevalent quality of life concerns included stiffness (90.2%), pain (83.1%), fatigue (62.4%), poor sleep (54.1%), concerns about appearance (50.6%), worry about the future (50.3%), and medication side effects (41%).
While there is no cure for ankylosing spondylitis, exercising is key to keeping your mobility and flexibility.
Ankylosing spondylitis symptoms may gradually worsen as you age. The condition is rarely disabling or life-threatening. Still, symptoms like joint pain may interfere with your ability to do the things you love. Early interventions can ease inflammation and pain.
Second Stage AS
As ankylosing spondylitis symptoms worsen (increased pain and stiffness), the disease may start to involve other parts of the body. For example, systemic inflammation can affect the eyes and your vision could become impacted.
Age of disease onset usually peaks in the second and third decades of life. Approximately 80% of patients with AS experience symptoms at ≤ 30 years of age, while only 5% will present with symptoms at ≥ 45 years of age.
According to the Spondylitis Association of America, people typically develop AS between 17 and 45 years of age. Most people develop AS in their 20s and 30s. In a 2022 study, the average age of onset worldwide was 26.