Not getting enough vitamin B12 to the point of a deficiency can cause a variety of serious symptoms including depression, joint pain, and fatigue.
Vitamin B complex is a type of non-antioxidant vitamin. We don't fully understand how this type of vitamin may treat arthritis-related conditions, but evidence from trials suggests that vitamins B3, B9 and B12 might be of some benefit for treating osteoarthritis, particularly in improving joint mobility and hand grip.
Reduced vitamin D intake has been linked to increased susceptibility to the development of rheumatoid arthritis (RA) and vitamin D deficiency has been found to be associated with disease activity in patients with RA.
A connection between vitamin b12 deficiency and RA has been suggested before, probably due to deficient nutrition and eventual malabsorption secondary to autoimmune mechanisms. Vitamin B12 may result in hyperhomocysteinemia which is an independent risk factor for cardiovascular disease.
Vitamin B12 specifically is a vitamin for nerves and joints – it protects the nerves, stimulates nerve regeneration, and could help reduce the pain from old injuries.
When choosing a supplement, look for either methylcobalamin or methyl B12. Studies have found that oral, intravenous, and intramuscular administration provide the same results. Treatment for fibromyalgia and rheumatoid arthritis, studies noted clinical benefits using between 1.5 and 6 mg per day.
Deficiency of vitamin B12 causes hyperhomocysteinemia (HHcy) [5,16], and elevated homocysteine is known to lead to an inflammatory state, a risk factor for coronary heart disease  and insulin resistance [17,18].
Untreated, vitamin B-12 deficiency can lead to neurological problems, such as persistent tingling in the hands and feet or problems with balance. It can lead to mental confusion and forgetfulness because vitamin B-12 is necessary for healthy brain function.
The study found that those with vitamin B12 concentrations below 148 pM/L had significantly lower average bone mineral density--at the hip in men, and at the spine in women--than those with concentrations above. The range of symptoms of B-12 deficiency includes anemia, balance disturbances and cognitive decline.
memory loss. pins and needles (paraesthesia) loss of physical co-ordination (ataxia), which can affect your whole body and cause difficulty speaking or walking. damage to parts of the nervous system (peripheral neuropathy), particularly in the legs.
Several vitamins have been studied for their effects on arthritis, including the antioxidant vitamins A, C, and E, and vitamins D and K.
Such is the case with vitamin D. When you aren't getting enough, you may get pain in your joints. Vitamin D's anti-inflammatory properties help relieve joint pain. Vitamin D also can help manage autoimmune conditions that affect the joints, including multiple sclerosis, rheumatoid arthritis, and Type 1 diabetes.
How long does it take to recover from B12 deficiency? Once you begin treating your vitamin B12 deficiency, it can take up to six to 12 months to fully recover. It is also common to not experience any improvement during the first few months of treatment.
Fish Oil or Omega-3 fatty acids EPA and DHA
EPA and DHA have been extensively studied for RA and dozens of other inflammatory conditions. One meta-analysis found that fish oil significantly decreased joint tenderness and stiffness in RA patients and reduced or eliminated NSAID use.
B12 deficiency affects sensory nerve function leading to motor dysfunction, which can cause muscle cramps and weakness.
If vitamin B12 deficiency is left untreated, it can cause lasting serious side effects that affect the nervous system and brain. More severe side effects of vitamin B12 deficiency include: Peripheral neuropathy. Degeneration of the spinal cord.
Over time, peripheral nerve damage resulting from vitamin B-12 deficiency can lead to movement problems. Numbness in the feet and limbs may make it hard for a person to walk without support. They may also experience muscle weakness and diminished reflexes.
Diet. Some people can develop a vitamin B12 deficiency as a result of not getting enough vitamin B12 from their diet. A diet that includes meat, fish and dairy products usually provides enough vitamin B12, but people who do not regularly eat these foods can become deficient.
It may present with sensory symptoms of limbs, difficulty in walking, stiffness of limbs, recurrent falls, memory impairment, visual blurring and psychosomatic illness including depression. A chronic pain syndrome can also occur due to Vit. B12 deficiency.
Pernicious anemia, one of the causes of vitamin B12 deficiency, is an autoimmune condition that prevents your body from absorbing vitamin B12. Left untreated, pernicious anemia can cause serious medical issues, including irreversible damage to your nervous system.
Taking magnesium can help to reduce arthritic pain and inflammation. It may be beneficial to take magnesium supplements or eat foods rich in magnesium if you are experiencing arthritic pain. Magnesium has not been shown to reverse arthritis.
Vitamin D is important for keeping bones strong and preventing injuries from falls. Research shows that people with low levels of vitamin D may have more joint pain.
Peripheral neuropathy is the most common presentation of vitamin B12 deficiency. Depending upon the type of nerve involved, it may present as pain, numbness, tingling, loss of sensation, decreased motor activity, or decreased muscle mass.