The organism that kills the most humans annually is the Mosquito, responsible for 725,000 to over 1 million deaths primarily through diseases like malaria, dengue, and Zika, while humans themselves are the second deadliest, causing around 400,000 homicides annually; snakes and dogs also rank high in animal-related deaths, according to sources like Visual Capitalist and BBC Science Focus Magazine.
In terms of the number of humans killed every year, mosquitos by far hold the record, being responsible for between 725,000 and 1,000,000 deaths annually. That is not to say these tiny insects set out to kill, however. Rather than killing directly, mosquitos are instead very frequent 'disease vectors'.
The Heaviest Hitters
A "silent killer" animal can refer to predators known for stealth like leopards, owls, or snakes (like the Common Krait), but also to seemingly harmless creatures like the venomous slow loris (a mammal) or even the disease-carrying mosquitoes, highlighting threats that are quiet, unassuming, or invisible, from stealth hunters to disease vectors.
1. Mosquito (780,000 deaths per year) The tiny mosquito is the most dangerous animal in the world as well as the most dangerous insect, claiming 780,000 lives annually.
The Amur leopard is one of the rarest big cats in the world, with only around 100 individuals left in the wild.
The plague that killed up to 75% of the population in some areas was the Black Death, a devastating pandemic (1346–1353) caused by the bacterium Yersinia pestis, which wiped out huge portions of Europe, Asia, and Africa, with some cities losing as many as three-quarters of their inhabitants in mere days.
Heart disease is the leading cause of death for men in the United States, accounting for 25 percent of all male deaths. Various factors, including smoking, high cholesterol levels and obesity, can cause heart disease.
Globally, Ischaemic Heart Disease (Coronary Artery Disease) is the number one cause of death, responsible for a significant portion of deaths, with cardiovascular diseases (CVDs) as the leading overall killer, followed by cancer, according to the World Health Organization (WHO). In the United States, heart disease also remains the top killer, while dementia and Alzheimer's are leading causes in places like Australia, with figures varying slightly by country and year.
The top predators in the world include the great white shark, known for its powerful bite and hunting technique, and the lion, which hunts cooperatively in prides. Other notable predators are the grizzly bear, famous for its strength and speed, and the killer whale, which uses sophisticated hunting strategies.
Most reported cases of man-eaters have involved lions, tigers, leopards, polar bears, and large crocodilians.
The number one killer in the world is cardiovascular disease (CVD), including heart disease and stroke, responsible for about one-third of all global deaths, claiming nearly 18-20 million lives annually, and remains the leading cause across all regions, according to WHO and World Heart Federation. While COVID-19 caused significant deaths in recent years, CVD has consistently held the top spot for decades, with increases seen globally, especially in younger populations.
The participants were monitored until they died or turned 90. At the end of the study, about 16% of the men and about 34% of the women survived to the age of 90. In fact, the authors found women who were taller than 5 feet 9 inches were 31% more likely to reach 90, compared to those who were under 5 feet 3 inches.
Although estimates vary, some sources believe that mosquitoes are responsible for up to 1 million human deaths per year, whereas snakes kill an estimated 100,000 and sharks a mere 10 (humans by the way are second behind the mosquito, causing 400,000 deaths every year).
Both septicemic plague (blood infection) and pneumonic plague (lung infection) had a nearly 100% death rate if left untreated, with pneumonic plague being the most contagious form, spreading through airborne droplets and being rapidly fatal. Untreated bubonic plague (swollen lymph nodes) could also develop into these deadly forms, leading to high mortality.
SARS-CoV-2 has officially claimed 5 million lives, but credible estimates place the pandemic's true death toll closer to 17 million. Either count secures COVID-19's position on our list of history's deadliest plagues.
The 1918 flu claimed an unfathomable 50 to 100 million victims worldwide, including an estimated 675,000 Americans.
Heart diseases were the most common cause, responsible for a third of all deaths globally. Cancers were in second, causing almost one-in-five deaths. Taken together, heart diseases and cancers are the cause of every second death.
Heart disease is America's No. 1 killer. Your gift now to the American Heart Association will help save lives by funding pioneering medical research, education and prevention information and more. Your donation is secure.
Globally, Ischaemic Heart Disease (Coronary Artery Disease) remains the world's biggest killer, but regionally, Dementia (including Alzheimer's) has recently become the leading cause of death in countries like Australia, surpassing heart disease for females and overall, while heart disease leads for males. Other top causes globally include stroke, respiratory infections, lung cancer, and chronic obstructive pulmonary disease (COPD).
Here are four animals at risk of extinction by 2050.
The so-called 'immortal' jellyfish, or Turritopsis dohrnii, can somehow reprogramme the identity of its own cells, returning it to an earlier stage of life. ADVERTISEMENT.
The woolly mammoth is the animal most prominently linked to a 2027 return, with biotechnology firm Colossal Biosciences aiming to have a cold-resistant elephant hybrid with mammoth traits walking the Earth by then, using gene-editing to help restore Arctic ecosystems. While not a true resurrection, this project aims to create a functional woolly mammoth-like creature, with other efforts also underway to de-extinct animals like the Tasmanian tiger (thylacine) and dodo.