Risk factors Having a family history of schizophrenia. Some pregnancy and birth complications, such as malnutrition or exposure to toxins or viruses that may impact brain development. Taking mind-altering (psychoactive or psychotropic) drugs during teen years and young adulthood.
In most people with schizophrenia, symptoms generally start in the mid- to late 20s, though it can start later, up to the mid-30s. Schizophrenia is considered early onset when it starts before the age of 18. Onset of schizophrenia in children younger than age 13 is extremely rare.
Criteria to diagnose schizophrenia
Delusions. Disorganized speech. Disorganized or catatonic behavior. Negative symptoms (emotional flatness, apathy, lack of speech)
Past studies have reported that offspring of affected mothers have a higher risk of schizophrenia than the offspring of affected fathers; however, other studies found no such maternal effect [Gottesman and Shields, 1976].
There's no sure way to prevent schizophrenia, but sticking with the treatment plan can help prevent relapses or worsening of symptoms. In addition, researchers hope that learning more about risk factors for schizophrenia may lead to earlier diagnosis and treatment.
Results: In patients with schizophrenia, MR imaging shows a smaller total brain volume and enlarged ventricles. Specific subcortical regions are affected, with reduced hippocampal and thalamic volumes, and an increase in the volume of the globus pallidus.
Stressful life events
Highly stressful or life-changing events may sometimes trigger schizophrenia. These can include: being abused or harassed. losing someone close to you.
Schizophrenia usually involves delusions (false beliefs), hallucinations (seeing or hearing things that don't exist), unusual physical behavior, and disorganized thinking and speech. It is common for people with schizophrenia to have paranoid thoughts or hear voices.
Borderline schizophrenia is held to be a valid entity that should be included in the DSM-III. It is a chronic illness that may be associated with many other symptoms but is best characterized by perceptual-cognitive abnormalities. It has a familial distribution and a genetic relationship with schizophrenia.
What is the life expectancy for people with schizophrenia? People with schizophrenia generally live about 15 to 20 years less than those without the condition.
Associative thinking problems are among the earliest warning signs of schizophrenia. People with associative thinking problems may have difficulty understanding cause-and-effect relationships. For example, they often don't recognize that their thoughts influence their feelings or behavior.
However, the impact of schizophrenia tends to be highest in Oceania, the Middle East, and East Asia, while the nations of Australia, Japan, the United States, and most of Europe typically have low impact.
Drug or alcohol use can make it worse. On the other hand, people with schizophrenia can be a danger to themselves. Suicide is the top cause of premature death among people with schizophrenia.
Although some people with schizophrenia suffer anxiety, it is impossible for people with anxiety disorders to develop schizophrenia as a result of their anxiety disorder. Anxiety sufferers should be reassured that they cannot develop schizophrenia as part of their anxiety state, no matter how bad the anxiety becomes.
Anxiety and affective symptoms are prominent features of schizophrenia which are often present in the prodromal phase of the illness and preceding psychotic relapses. A number of studies suggest that genetic risk for the disorder may be associated with increased anxiety long before the onset of psychotic symptoms.
People with schizophrenia experience psychosis, which means they can have serious problems with thinking clearly, emotions, and knowing what is real and what is not. This can include hearing or seeing things that are not there (hallucinations), and having very strange beliefs that are abnormal or not true (delusions).
Research suggests that schizophrenia occurs due to a combination of genetic and environmental factors, which can cause abnormal development in the brain. In people with these risk factors, severely stressful life events, trauma, abuse, or neglect may trigger the condition.
PET is an important functional imaging technique that can be used to investigate neurotransmitter receptors and transporters directly by mapping human brain function. PET is increasingly being used greatly to advance our understanding of the neurobiology and pathophysiology of schizophrenia.
Brain tumors may present with psychotic symptoms that resemble schizophrenia. Although psychosis secondary to brain tumor is relatively rare, the frequent lack of neurological findings can lead to misdiagnosis. Psychosis secondary to brain tumor is more common and also harder to accurately diagnose in the elderly.
Furthermore, schizophrenia patients often have a comorbid sleep disorder, including insomnia, obstructive sleep apnea, restless leg syndrome, or periodic limb movement disorder.
A review of worldwide studies has found that add-on treatment with high-dose b-vitamins - including B6, B8 and B12 - can significantly reduce symptoms of schizophrenia more than standard treatments alone.
Medications are the cornerstone of schizophrenia treatment, and antipsychotic medications are the most commonly prescribed drugs. They're thought to control symptoms by affecting the brain neurotransmitter dopamine.
Drastic changes in behaviour may occur, and the person can become upset, anxious, confused, angry or suspicious of those around them. They may not think they need help, and it can be hard to persuade them to visit a doctor. Read more about understanding psychotic experiences.