1 Portgas D. Ace's death shocked viewers worldwide. Portgas D. Ace was the son of Gol D. Roger, a beloved central member of Whitebeard's Crew, the Spade Pirates' Captain, and most of all, the brother of Luffy.
While Ace was rescued, he ended up giving his life for Luffy to protect him from Akainu. Despite everything, Ace died free of regrets, and the fact that he finally knew that it was good to be born meant that he lived a fulfilling life.
5 Pudding Betrays The Straw Hat Pirates
In the Whole Cake Island arc, Pudding tried to help the Straw Hat Pirates, however, she was actually leading them into a trap. She betrayed not just the Straw Hat Pirates but Sanji as well and was planning on killing him and his entire family.
Fighting Crocodile in the Kingdom of Alabasta
When Luffy first faced Crocodile, he was unprepared and weak. Crocodile drained Luffy of moisture with his sand powers and left him for dead in quicksand.
Sir Crocodile was the main antagonist of the Alabasta arc of the series and the first Shichibukai that Luffy took down. Crocodile is easily one of the most difficult fights that Luffy has ever fought as he lost to him twice. In fact, Luffy would've died both the times had luck not been on his side.
Buggy is the captain of the Buggy Pirates and one of the Four Emperors of the Sea. A person who has not met Buggy can easily be fooled by his titles, but those who have know that he is one of the weakest characters in the series.
Zoro feels regret about this loss. At that moment, Zoro lifts up his sword to salute his captain with tears rolling down the side of his face as he promises never to lose again.
The biggest issue fans have with One Piece is the pacing. Many scenes are dragged out to a ridiculous degree and most episodes also dedicate the first five minutes to recap. Each episode may be twenty-four minutes, but in the most extreme cases, episodes will only have ten minutes of new content.
1) Zeno - Beyond estimation (universal)
He has obliterated multiple universes with little effort. Despite his plushy appearance, this deity easily has one of the highest and most immeasurable kill counts of all anime characters.
Neon Genesis Evangelion's Shinji is one of the most notable crybabies across anime. He gets overwhelmed often and has a lot of issues coping with social situations. Of course, Shinji has many reasons for expressing his melancholy so frequently.
The Yonko are the four strongest pirates in One Piece who rule the New World like Kings. Out of all the pirates in the world, they possess the greatest influence on the seas and have bounties that far surpass the billion berry mark.
1 Easiest: Luffy Vs.
Holdem, one of the Headliners of Kaido, was faced by Luffy's wrath during the First Act of the Wano Country arc. Having hurt Tama, Holdem getting beaten up by Luffy was all but certain.
Usopp remains to be the weakest member of the Straw Hat Pirates. In Wano, the vast majority of the members of the Straw Hat crew received good power-ups. However, Usopp was one of the members who did not receive any power-up and thus is lagging behind.
1 Shirahoshi
Her ability is known to be great enough to destroy the entire world and Luffy is her guide. Her existence alone can bring the entire world to heel and now that she has gained full control over her ability, it goes without saying that she is quite likely the greatest ally that Luffy has so far.
In order to save the Straw Hat Pirate from the warden Magellan's venom, Emporio Ivankov used their Devil Fruit powers to alter the hormones in the boy's body to strengthen his immune system. The process was excruciating, lasted for hours, and ultimately took approximately 10 years off of Luffy's life expectancy.
No, he never killed anyone. The reason why he never kills anyone is that he is leaving them another chance to achieve their dreams. This was also stated by Oda in SBS vol.
Conis and the rest of Skypiea witnessed Luffy completely destabilize Enel's attack. She then witnessed Luffy finally defeat Enel by punching the god straight into the golden bell.