Diabetes mellitus is not a risk factor for osteoarthritis.
Age—The risk of developing OA increases with age. Gender—Women are more likely to develop OA than men, especially after age 50. Obesity—Extra weight puts more stress on joints, particularly weight-bearing joints like the hips and knees. This stress increases the risk of OA in that joint.
Non-modifiable risk factors for OA include age, sex, ethnicity, genetics, previous history of injury or joint trauma. Potentially modifiable risk factors for OA include excess weight, certain occupations and sports, joint injury (injury prevention), joint malalignment and quadriceps weakness.
3. Risk factors of OA. The risk factors of OA can be divided into person-level factors, including age, gender, obesity and genetics and diet, and joint-level factors, including injury and abnormal loading of the joints [18]. Knee malalignment is the strongest predictor of progression of knee OA.
The aging changes in joint tissues that contribute to the development of OA include cell senescence that results in development of the senescent secretory phenotype and aging changes in the matrix, including formation of advanced glycation end-products that affect the mechanical properties of joint tissues.
The dietary inflammatory index is characterized by decreased use of fruits and vegetables and increased use of meat, fats, oils, and sweets. Higher dietary inflammatory index values are found to be associated with a higher prevalence of knee osteoarthritis [34, 35].
Osteoarthritis does not usually cause fevers, weight loss, or very hot and red joints. These features suggest some other condition or type of arthritis.
Cause of Osteoarthritis
Osteoarthritis happens when the cartilage and other tissues within the joint break down or have a change in their structure. This does not happen because of simple wear and tear on the joints. Instead, changes in the tissue can trigger the breakdown, which usually happens gradually over time.
Risk factors for osteoarthritis
being overweight or obese. a previous significant injury to the joint. increasing age. repetitive movements associated with an occupation.
A poor diet, high blood pressure and cholesterol, stress, smoking and obesity are factors shaped by your lifestyle and can be improved through behavior modifications. Risk factors that cannot be controlled include family history, age and gender.
3.2, health risk factors and their main parameters in built environments are further identified and classified into six groups: biological, chemical, physical, psychosocial, personal, and others.
Knees. The knees are among the joints most commonly affected by osteoarthritis. Symptoms of knee osteoarthritis include stiffness, swelling, and pain, which make it hard to walk, climb, and get in and out of chairs and bathtubs.
Post-traumatic arthritis affects more than 5 million people every year. It's around 10% of all osteoarthritis cases. You're seven times more likely to develop arthritis in an injured joint than people who've never experienced trauma to their joint.
Osteoarthritis, the most common type of arthritis, is caused primarily by age-related wear-and-tear that involves the deterioration of the smooth outer covering of bone, known as cartilage.
While the exact cause of arthritis is unknown, experts have identified certain risk factors that can lead to the development of arthritis. Genetics, unhealthy body weight, joint injury or overuse, and smoking are all factors that may put you at greater risk.
regular exercise. losing weight if you're overweight. wearing suitable footwear. using special devices to reduce the strain on your joints during your everyday activities.
Overweight and Obesity
Excess weight can also make knee osteoarthritis worse. Extra weight puts more stress on joints, particularly weight-bearing joints like the hips and knees.
Osteoarthritic joints have low levels of aggrecan, proteoglycan, type-II collagen, and runt-related transcription factor 1(RUNX1).
The joint at the base of the thumb is not usually affected by osteoarthritis.
Exercise (even strenuous exercise) on normal joints does not result in a substantially increased likelihood of arthritis.
Women who go through menopause often gain weight, and the increased stress on the joints may explain the rise in osteoarthritis seen among women after age 55. By the time a woman reaches 65, she is twice as likely as a man to experience osteoarthritis symptoms.