As an antihistamine, hydroxyzine blocks the effects of histamine in your body, which makes you sleepy. (Think about how you feel after taking Benadryl or Nyquil.) Serotonin is a chemical that affects your mood. Hydroxyzine's unique effect on serotonin is likely why it's the only antihistamine used for anxiety.
Hydroxyzine is an antihistamine. It is approved for the treatment of anxiety. However, hydroxyzine is also used to treat difficulty sleeping, nausea, vomiting, itching, skin rash, and allergies.
Benzodiazepines (also known as tranquilizers) are the most widely prescribed type of medication for anxiety. Drugs such as Xanax (alprazolam), Klonopin (clonazepam), Valium (diazepam), and Ativan (lorazepam) work quickly, typically bringing relief within 30 minutes to an hour.
The most prominent of anti-anxiety drugs for the purpose of immediate relief are those known as benzodiazepines; among them are alprazolam (Xanax), clonazepam (Klonopin), chlordiazepoxide (Librium), diazepam (Valium), and lorazepam (Ativan).
Benadryl is an antihistamine that may cause you to feel sedated and drowsy. This doesn't mean it calms anxiety symptoms, though. There's simply no scientific evidence to support its use for anxiety. In fact, it's not recommended for this purpose.
Most antihistamines are known to cause drowsiness during the day. This may be a problem for people who operate heavy machinery or otherwise must remain alert. These drugs also aren't effective for severe anxiety or depression, and they're not a long-term treatment for any anxiety disorder.
Magnesium reduces stress hormones in the brain to lessen anxiety, restlessness, mood swings, memory loss, depression, insomnia, and a host of other mental health issues. Magnesium limits the release of cortisol, which is the primary stress hormone, and prevents it from reaching the brain.
Chamomile: Widely regarded as a mild tranquilizer and sleep-inducer, chamomile has a sedative effect. According to studies, it can significantly reduce anxiety symptoms. It's one of the most popular herbs used in herbal teas and one of the most ancient medicinal herbs.
Benzodiazepines most commonly used to treat anxiety disorders are clonazepam (Rivotril)*, alprazolam (Xanax) and lorazepam (Ativan). Also used are bromazepam (Lectopam), oxazepam (Serax), chlordiazepoxide (once marketed as Librium), clorazepate (Tranxene) and diazepam (Valium).
In the United States, 55% to 94% of patients with anxiety disorders are treated with benzodiazepines.
A second therapeutic candidate, LYT-310 (oral cannabidiol), is expected to enter the clinic in Q4 of 2023.
First-generation antihistamines, such as diphenhydramine, can be used to treat general anxiety disorder. Beta-blockers, such as propranolol, are used to treat performance anxiety, a kind of social anxiety disorder, and are sometimes used for panic disorder.
There are several over-the-counter options for managing anxiety. Here are some natural herbs and supplements that may help: Magnesium: Magnesium helps regulate neurotransmitters and reduces symptoms of anxiety. Ashwagandha: Ashwagandha is an adaptogenic herb that helps the body cope with stress.
Vitamins B9 and B12 are both thought to treat symptoms of anxiety. Folic acid has many uses in the body, and B9 deficiency has been linked to higher levels of anxiety and depression. When taken in conjunction with B12, these B super-vitamins help metabolize serotonin, which is important for mood regulation.
Magnesium deficiency can have a spiraling effect.
If we don't get enough magnesium from our food, we are more vulnerable to high levels of stress and anxiety. More stress can lead us to lose even more magnesium through the kidneys in a process of urinary extraction.