DAXXIFY (Daxxify) is generally considered the longest-lasting type of Botox, with results often extending up to 6 months or longer, compared to traditional Botox (Botox Cosmetic), Dysport, and Xeomin, which typically last 3 to 4 months. DAXXIFY uses a unique peptide formulation that allows it to bind more effectively to muscle receptors, potentially leading to a longer duration of effect, although individual results vary.
Botox Over 20 Years: What to Expect
With 20 years of Botox use, many people look younger than they would have without treatment. Muscle Atrophy and Adaptation: After long-term Botox use, some facial muscles may experience mild atrophy due to limited activity.
Treatment differences
There aren't many differences between Botox and Dysport. You may find that Dysport is less expensive than Botox, but that varies from doctor to doctor. Some people may feel that Dysport lasts longer, but Dr. Khetarpal says each type of treatment lasts for about four months.
Botox and Dysport typically last longer than Xeomin due to their protein content. However, those same proteins may decrease the effectiveness of the chemical and eventually diminish results.
After 10 years of regular Botox, you generally look younger with smoother, brighter skin and significantly fewer deep wrinkles because the muscles have been trained not to frown, but you might experience subtle muscle weakening, less facial expression (which some find positive), and potentially thinner skin or more visible veins in some areas, while the skin remains refreshed and well-maintained.
Potential Risks and Side Effects of Botox for Older Adults
Some rare but potential risks for patients over the age of 65 include: Reactions At the Injection Site—Bruising, pain, and swelling around the injection site are the most common side effects of a Botox treatment.
If it's right for you, The Look of 3® is an opportunity to be treated in 3 areas, with 64 units, at least 3 times a year. For moderate to severe forehead lines, frown lines, and crow's feet in adults. *Treatments should be spaced 90 days apart.
Xeomin is considered to be equally as potent as Botox and is used at a 1:1 ratio for treatment. For example, 20 units of Botox equals 20 units of Xeomin. Xeomin is also a purer form of botulinum toxin because it does not contain complex proteins (more below, see resistance) or preservatives.
Dysport: Quick Diffusion and Natural Results
Dysport injections spread more than Botox, which can be advantageous for treating larger areas such as extensive forehead lines. The diffusion can lead to a more natural look, less “frozen” than the results of some other neuromodulators.
Dysport may wear off quickly for a number of reasons, including a fast metabolism, high activity level or muscle activity, smoking, lower dosage, too frequent treatments, and the experience of the treatment provider.
Some people are discouraged by the idea of getting injections because they think the effects do not last very long. But, studies have shown that taking zinc supplements will prolong Botox results! Keep reading to learn about what Botox is and how zinc supplements can make a difference in the injection results.
These cosmetic treatments have the same active ingredient: Botulinum toxin. However, Dysport is diluted compared to Botox and is typically cheaper than the latter per unit.
Gen Z is saying "no" or "not yet" to Botox due to a desire for natural beauty, individuality, and healthy aging, rejecting the overdone "Instagram Face," fearing irreversible damage, and prioritizing serious skincare and non-toxic alternatives over the costly, repetitive nature of injectables, despite social media pressure to do them. They're focused on "skinimalism," collagen support, and avoiding the potential for unnatural or frozen looks often seen online, opting for treatments that enhance rather than mask their natural features.
The Bottom Line on Botox
Risks aside, it's worth noting that those 65 and up might not receive the results they're looking for after receiving Botox, which is one reason the FDA lists this age as their recommended cut-off. Ultimately, the decision to receive or reject Botox at any age rests with you and your doctor.
1) Forehead
When too much Botox is used in the forehead, it can overly relax the muscles, leading to a lack of natural movement and expression. In severe cases, excessive Botox in the forehead can increase the heaviness of the upper eyelids, causing them to become hooded.
Yes — Botox always leaves your system. Once injected, Botox binds to the targeted muscles and blocks nerve signals for a period of time. Over the course of 3–4 months, your body naturally breaks it down, and full muscle activity returns. No residue of Botox remains in your system permanently.
Some of the most common side effects of Dysport include injection site pain, swelling around the eyelids, rash, infection, and headaches. These side effects should go away within a few days. More serious side effects of Dysport include nausea, sinusitis, and upper respiratory issues.
"More natural looking” is such a subjective phrase. Think of it this way instead. Because you're using BOTOX to treat different areas than you would use Dysport and vice versa, it's almost impossible to determine that one looks better than the other.
A good price to pay for Botox typically ranges from $10 to $20 per unit, but the total cost depends on how many units you need. Most people require 20 to 60 units for common treatment areas like forehead lines, crow's feet, and frown lines.
Dysport costs $4-$8 per unit (more units needed), Botox $12-$20, and Xeomin $10-$17, with similar effectiveness (85-95% satisfaction) and side effects (<5% incidence). Duration averages 3-4 months for Dysport/Botox, up to 6 for Xeomin.
A Botox unit is simply a standard measure of the product's strength. It is not a measurement of liquid volume, like a cubic centimeter (cc). Think of it as a "dose" of medicine. This standardization is crucial because it allows practitioners to deliver precise, consistent, and repeatable results for every client.
From 2025, following a landmark decision by the Nursing and Midwifery Council (NMC), new regulations for aesthetic injectables will ban nurses from prescribing botulinum toxin remotely face-to-face consultations will be mandatory before treatment.
The "Botox 4-hour rule" means you should stay upright and avoid pressure or lying down for at least four hours after injections to prevent the neurotoxin from migrating from the treated muscles to unintended areas, which can cause side effects like drooping or uneven results. This helps the Botox settle precisely where it's needed for optimal wrinkle-smoothing effects, so avoid bending, rubbing, or strenuous activity during this critical period.
You may need repeat treatments every 3-4 months to maintain your best results. We don't recommend treatments spaced more frequently than three months, or you could develop a resistance to the Botox's effects.