Depending on the affected organ, an acute problem can result in permanent tissue injury (“damage”), e.g., heart failure, stroke with loss of function, or chronic kidney failure.
Certain cells and processes of the immune system have been identified as playing a role in lupus. Kidneys About one half of people with lupus experience kidney involvement, and the kidney has become the most extensively studied organ affected by lupus.
Cardiovascular disease, not lupus itself, is the number one cause of death in people with lupus. (It is actually the number one cause of death around the world.) The number two cause of death for people with lupus is infection.
Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disease that can affect almost every organ in the body. Its complications can often be fatal.
serositis – inflammation of the lining around the lungs (pleuritis) or inflammation of the lining around the heart that causes chest pain that is worse with deep breathing (pericarditis) musculoskeletal – joint pain and swelling. kidney disorder – persistent protein or evidence of lupus involvement on kidney biopsy.
Lupus occurs when the immune system, which normally helps protect the body from infection and disease, attacks its own tissues. This attack causes inflammation, and in some cases permanent tissue damage, which can be widespread – affecting the skin, joints, heart, lung, kidneys, circulating blood cells, and brain.
Lupus can cause serious kidney damage, and kidney failure is one of the leading causes of death among people with lupus. Brain and central nervous system. If your brain is affected by lupus, you may experience headaches, dizziness, behavior changes, vision problems, and even strokes or seizures.
However, the majority of people with lupus can expect a normal or near-normal life expectancy. Research has shown that many people with a lupus diagnosis have been living with the disease for up to 40 years.
Lupus is not a hereditary condition. However, genetic factors play an important role in developing lupus, and certain inheritable genes may increase a person's risk of lupus. Lupus is a chronic autoimmune condition in which the immune system mistakenly attacks healthy tissue.
People with lupus can have cognitive symptoms, like having a hard time thinking clearly or remembering things. This is also called “brain fog” or “lupus fog,” and it often comes and goes over time. In some people, lupus fog can be present for many years.
Common triggers include:
Being out in the sun or having close exposure to fluorescent or halogen light. Infection. Injury. Stopping your lupus medicines.
Systemic lupus erythematosus (SLE) is an autoimmune disease with an increased risk of hospitalization. Multiple studies have reported SLE flare, infection, and cardiovascular (CV) events as the most common reasons for hospitalization.
Lupus and some lupus medicines can cause hepatitis, or inflammation of the liver. Many people with hepatitis don't notice any symptoms, but some people have these symptoms: Fatigue (feeling tired) Jaundice (yellow skin or eyes)
Palliative (pronounced PAH-lee-uh-tiv) care is a health care approach that tends to the physical, emotional, social and spiritual needs of a person with an illness and the needs of his or her family. It can be offered to people at any age and at any point in an illness such as lupus.
Sudden death in lupus patients is uncommon in the literature. A few cases of sudden death not due to myocardial infarction have been reported. One of them was a patient with both myocarditis and thyroiditis who apparently had myocardial failure and arrhythmias leading to death.
With age, symptom activity with lupus often declines, but symptoms you already have may grow more severe. The accumulation of damage over years may result in the need for joint replacements or other treatments.
Lupus may get worse very quickly. There is no way to tell when a flare will happen or how bad it will be. When you have a lupus flare, you may have new symptoms as well as symptoms you have had in the past. Learn your body's signs of a flare, such as joint pain, a rash, a fever, or being more tired.
While there is no cure for lupus, people with the disease are living longer, healthier lives than in years past. Today, most people diagnosed with lupus in adulthood can expect to live a normal life span. Only 10 to 15 percent of people with lupus die prematurely due to complications of the disease.
Because lupus is an autoimmune disease, it causes your body to attack itself. This can lead to organ damage over time. Parts of the body that can be impacted by lupus can include the skin, blood, joints, kidneys, brain, heart and lungs. Skin: Skin problems are a common feature of lupus.
Lupus hepatitis causes nonspecific reactive hepatic damage due to liver vasculitis and complement deposition in the liver tissue [6]. It is a rare condition, and its occurrence as the first presentation of adult lupus in patients is considered extremely rare [6].