It painlessly delivers radiation to treat some types of cancer. Proton therapy is a promising new type of cancer treatment, but its possible benefit over traditional radiation therapy is still being studied. Research is ongoing in clinical trials to see how it compares.
Stereotactic body radiation therapy (SBRT) is a new approach that is being applied to some types of cancer which differs from more traditional therapy in a variety of ways.
SBRT is a new EBRT technique that is made possible by improved radiation accuracy and improved therapeutic ratios for many tumor sites. This technique delivers precise and very high individual doses of radiation by focusing multiple radiation beams on the target form different directions.
SBRT is one of the most advanced forms of radiation therapy available for cancer patients.
Radiotherapy is usually given as a number of individual treatments delivering a small dose of radiation daily over several weeks. Most people have 5 treatments a week (one treatment a day from Monday to Friday), with a break at the weekend.
Types of cancer that are treated with radiation therapy
Brachytherapy is most often used to treat cancers of the head and neck, breast, cervix, prostate, and eye. A systemic radiation therapy called radioactive iodine, or I-131, is most often used to treat certain types of thyroid cancer.
Embryonal tumors, as well as tumors composed of rapidly growing cells, are sensitive to radiotherapy. Lymphoid cells are particularly susceptible to radiation. On the contrary, neurosarcoma, glioma and melanoma are radioresistant.
Results: Of the analyzed 963 patients who received palliative radiotherapy, 2.4% (n = 23) survived at least 5 years, with a large majority of these surviving patients (73.9%, n = 17) being free of disease.
The most common type of radiation therapy is external-beam radiation therapy. It delivers radiation from a machine outside the body.
Radiation therapy remains an important component of cancer treatment with approximately 50% of all cancer patients receiving radiation therapy during their course of illness; it contributes towards 40% of curative treatment for cancer.
The most radiation-sensitive organs include the hematopoietic system [4], the gastrointestinal (GI) system [5], skin [6, 7], vascular system [8, 9], reproductive system, and brain [10–12].
Lymphocytes (white blood cells) and cells which produce blood are constantly regenerating, and are, therefore, the most sensitive. Reproductive and gastrointestinal cells are not regenerating as quickly and are less sensitive.
Don't wear tight clothing over the treatment area. It's important not to rub, scrub or scratch any sensitive spots. Also avoid putting anything that is very hot or very cold—such as heating pads or ice packs—on your treated skin.
Resistance can occur when cancer cells—even a small group of cells within a tumor—contain molecular changes that make them insensitive to a particular drug before treatment even begins. Because cancer cells within the same tumor often have a variety of molecular changes, this so-called intrinsic resistance is common.
Most side effects generally go away within a few weeks to 2 months of finishing treatment. But some side effects may continue after treatment is over because it takes time for healthy cells to recover from the effects of radiation therapy. Late side effects can happen months or years after treatment.
During radiation treatment, the mean weight loss was 4.33 kg, and 53.6% (1303) patients had high weight loss (HWL; ΔW≥5%). The proportion of HWL was higher in patients with advanced T stage, N stage, high BMI level and who received chemotherapy.
Feeling very tired and lacking energy (fatigue) for day-to-day activities is the most common side effect of radiation therapy to any area of the body. During treatment, your body uses a lot of energy dealing with the effects of radiation on normal cells.
Breast cancer: Women with breast cancer have an overall 30% chance of recurrence. Many cases happen within five years of completing the initial treatment. Cervical cancer: Of those with invasive cervical cancer, an estimated 35% will have a recurrence.
Typically, people have treatment sessions 5 times per week, Monday through Friday. This schedule usually continues for 3 to 9 weeks, depending on your personal treatment plan. This type of radiation therapy only targets the tumor. But it will affect some healthy tissue surrounding the tumor.