In 2023, new developments for Multiple Sclerosis (MS) included the FDA approval of Tyruko (natalizumab-sztn) (the first MS biosimilar), progress in adaptive clinical trials for progressive MS testing drugs like metformin, and exploration of AI for MRI analysis; while new treatments aren't always blockbuster drugs, 2023 marked significant steps in personalized approaches, biosimilar access, and advanced research for better MS management.
There is no cure for multiple sclerosis (MS). However, progress has been made in developing new medicines to treat it. Research is ongoing to develop new and better disease-modifying therapies (DMTs) for this disease of the central nervous system. DMTs can reduce the frequency and severity of MS attacks.
You may experience an uncomfortable squeezing sensation known as the MS hug. If you have pain on the side of your face or something that feels like earache or toothache, we call this trigeminal neuralgia. Other pain can come from muscle spasms or if your MS impacts your posture.
Epileptic seizures are more common in people who have multiple sclerosis (MS) than in those who don't have MS . While it's estimated that less than 3 percent of people without MS have seizures, about 2 to 5 percent of people with MS are thought to have active seizures.
One of the most exciting developments in multiple sclerosis treatment in 2025 is autologous hematopoietic stem cell transplantation (AHSCT). In people with relapsing MS, this method has shown: High rates of disease remission. Long-term freedom from relapse and MRI activity.
Lifestyle and home remedies
Kesimpta and Ocrevus are both effective for relapsing MS, but Kesimpta may offer advantages in reducing relapse rates and MRI disease activity. Ocrevus remains the only option approved for primary progressive MS.
By the time patients start seeking care for multiple sclerosis (MS), the disease has already been damaging their brains for years. But until recently, scientists didn't understand which brain cells were being targeted or when the injury began.
Personal Independence Payment (PIP)
You can spend it on whatever you need, such as paying for support to remain independent during relapses, or to help with extra costs such as heating, transport or help around the house. Some people with MS assume they can't get PIP because they're 'not disabled enough'.
However, triggers that may provoke or worsen a multiple sclerosis attack include:
Some people with MS lose sensation in their tongue. Some health care providers refer to MS-related tongue issues as “MS tongue.” Loss of sensation or numbness can make it difficult to move your tongue when you speak, chew, or swallow. Tongue numbness may also diminish sense of taste.
Hearing problems aren't a common MS symptom. But people with MS can sometimes experience problems including tinnitus, increased sensitivity to sound and loss of hearing.
1800 mg of Gabapentin a day is a common dose to help neuropathic pain. The FDA has approved PreGabalin and Cymbalta for treatment of diabetic related peripheral neuropathic pain and fibromyalgia, but we also use these medications for MS neuropathic pain in an off label fashion.
For those with MS, avoiding too much exercise is a big concern. Too much activity can cause fatigue and worsen symptoms. It's important to listen to your body and know when you've done too much. Pacing activities and taking breaks helps manage energy.
Over 90% of people with MS have elevated levels of an antibody called intrathecal immunoglobulin G (IgG).
For many, fatigue is considered to be the single most debilitating symptom, surpassing pain and even physical disability. Fatigue also imposes significant socioeconomic consequences, including loss of work hours and in some instances, loss of employment.
The SMI Council Tax discount tends to include those impacted by the likes of dementia, Alzheimer's, Parkinson's, severe learning difficulties, multiple sclerosis, complications from cerebral palsy and strokes. However you might have one or more conditions that fall into both categories.
There are two main types of government support available for eligible people who are aged 65 years or older and living with MS in the community: Home care packages. Commonwealth Home Support Programme (CHSP)
As well as disability benefits, there's other financial help out there that might make living with MS easier. Find out more about free public transport, disabled facilities grants, help with keeping warm in winter, prescription charges and dealing with debt.
Multiple sclerosis (MS) is an inflammatory disorder that affects the brain and spinal cord (the central nervous system).
MS and emotions
You may easily burst into tears, or suddenly get very angry. These emotions may build up very quickly, and you may have no control over them. Sometimes, these emotions are related to what you're actually feeling.
5 Tips for Living Better with MS: Patients and Caregivers
How long you can take Ocrevus will also depend on any side effects you experience. Ocrevus can cause mild and serious side effects. The 10-year safety profile for Ocrevus is similar to the profile from its initial studies. In other words, long-term Ocrevus use does not further increase the risk of serious side effects.
Kesimpta (ofatumumab) is a disease modifying drug (DMD) for relapsing remitting MS. You take Kesimpta as an injection under the skin once a month.