New knee osteoarthritis treatments focus on cartilage repair (Sprifermin, ACI), advanced injections like biolubricants (Arthrosamid) and targeting inflammation (Pentosan Polysulfate Sodium (PPS)), and novel procedures such as Genicular Artery Embolization (GAE) to reduce pain and delay surgery, alongside repurposed drugs like Metformin.
The device is called the MISHA (Medial Implantable Shock Absorber) Knee System, an implantable shock absorber that reduces weight on the knee joint, reduces pain and improves function.
Osteoarthritis: This condition can result in several symptoms, such as itching, pain, swelling, and stiffness in the joints. It can also cause the joints to wear down over time gradually.
The #1 mistake making bad knees worse is excessive rest or inactivity, which weakens supporting muscles, leading to stiffness and instability, creating a vicious cycle of pain and dysfunction, even though it feels counterintuitive; the solution involves controlled movement and strengthening exercises (like walking, swimming) to support the joint. Other major mistakes include wearing unsupportive shoes, carrying excess weight, and performing movements that involve twisting.
As of 2025, PRP has moved beyond being an experimental therapy. It is now recognized as one of the leading biologic options for knee osteoarthritis. Ongoing studies are exploring how PRP can be combined with stem cell therapy or other regenerative techniques to further enhance outcomes.
The authors concluded that diclofenac at 150 mg/day is the best NSAID in terms of both pain and function amelioration in OA, superior to the maximum doses of frequently used NSAIDs, including ibuprofen, naproxen and celecoxib.
7 alternatives to knee replacement surgery
Vitamin D deficiency is linked to knee pain. Adequate nutrition is essential for maintaining healthy knees. Knee pain can be managed and prevented through dietary adjustments. Understanding the link between nutrition and knee health is critical.
If you only have time for one exercise to strengthen your knees, hop on a bike or do a set of simple air squats. Doing squats or mini-squats strengthens the primary muscles that support your knees. As we get older, knee discomfort and stiffness are common issues, caused by arthritis and wear and tear after years of use ...
It is not an infectious or contagious condition. Osteoarthritis is primarily a localized condition that occurs within a specific joint. However, it is important to note that while osteoarthritis does not spread from joint to joint, it can affect multiple joints in the body simultaneously.
For severe pain, topical NSAIDs likely won't match the effects of oral meds, but those who have mild to moderate arthritis may find relief. They come in OTC and prescription gels and creams. A Cochrane review found that diclofenac or Voltaren, ibuprofen and ketoprofen gels are the most effective.
In addition to pain, other common sensations are heaviness, numbness, or aching in the leg muscles.
Knee gel injections are a treatment for arthritis in your knee joint. Technically, they're hyaluronic acid injections. Hyaluronic acid is a natural lubricant found in many of your body's tissues. It's also the main ingredient in synovial fluid, which lubricates your joints.
Physical therapy (PT): PT can help you strengthen the muscles around your knee to support it better. Increasing your strength and flexibility will reduce pressure on your joint and can reduce pain.
ACL surgery is considered challenging to recover from due to several factors. The surgery involves repairing or reconstructing a vital ligament in the knee, which is essential for knee stability during physical activities.
What is the impact of vitamin B12 on joint pain? Vitamin B12 supplementation proves to be important in the therapeutic approach to joint pain and promotes the achievement of significant improvements in acute and chronic cases, due to its analgesic, neuroprotective and anti-inflammatory effect.
Here are 10 unexpected signs of a vitamin D deficiency that may surprise you.
The #1 mistake making bad knees worse is excessive rest or inactivity, which weakens supporting muscles, leading to stiffness and instability, creating a vicious cycle of pain and dysfunction, even though it feels counterintuitive; the solution involves controlled movement and strengthening exercises (like walking, swimming) to support the joint. Other major mistakes include wearing unsupportive shoes, carrying excess weight, and performing movements that involve twisting.
Here are seven simple ways to keep your joints lubricated as you get older.
While surgical intervention, such as knee replacement, may be necessary for severe cases, there are several non-surgical treatment options available that can help manage the condition and provide relief from the associated pain. One non-surgical treatment option that has shown promising results is viscosupplementation.
PRP therapy has emerged as a promising alternative to cortisone injections. This innovative treatment involves harvesting a patient's blood, separating the platelets, and injecting the concentrated platelet-rich plasma into the injured area. Platelets contain growth factors that promote tissue repair and regeneration.
Applying heating pads, taking hot baths or showers, or using warm paraffin wax can temporarily relieve join pain. Be careful not to burn yourself. Limit heating pad use to 20 minutes at a time. Ice packs can help lessen pain and inflammation, especially after physical activity.
Botulinum toxin is used to treat both osteoarthritis and autoimmune arthritis (such as rheumatoid arthritis) of the knee. The medication is injected into the knee joint. After a single treatment, patients may experience less pain and greater range of motion for three to 12 months. The treatment can be repeated.
Conclusion: Celecoxib 200 mg daily is as effective as diclofenac 150 mg daily for relieving signs and symptoms of OA of the knee, including pain, and has a rapid onset of action. However, celecoxib appears to have a superior safety and tolerability profile.