INVEGA TRINZA® (paliperidone palmitate) a 3-month injection, is an atypical antipsychotic indicated for the treatment of schizophrenia in patients after they have been adequately treated with INVEGA SUSTENNA® (1-month paliperidone palmitate) for at least four months.
How do they work? Antipsychotic injections for schizophrenia target neurotransmitters, including dopamine, serotonin, and glutamate, which may alleviate psychosis symptoms. After the injection, the medication slowly releases into the bloodstream for 2–12 weeks.
ABILIFY MAINTENA® (aripiprazole) is a prescription medicine given by injection by a healthcare professional for: treatment of schizophrenia in adults.
INVEGA HAFYERA™ (6-month paliperidone palmitate) is a prescription medicine given by injection every 6 months by a healthcare professional and used to treat schizophrenia.
INVEGA TRINZA® (paliperidone palmitate) a 3-month injection, is an atypical antipsychotic indicated for the treatment of schizophrenia in patients after they have been adequately treated with INVEGA SUSTENNA® (1-month paliperidone palmitate) for at least four months.
The most common side effects that occurred during INVEGA® clinical trials in the treatment of schizophrenia in adolescents were: sleepiness, restlessness, abnormal muscle movements (including twitching), stiffness, anxiety, weight gain, and fast heartbeat.
Additionally, the FDA approved Otsuka America Pharmaceutical and Lundbeck's new drug application (NDA) for Alify Asimtufii (aripiprazole) for both schizophrenia and maintenance monotherapy treatment of bipolar I disorder in adults.
Cognitive behavioral therapy, also known as CBT, may be a treatment option for people with schizophrenia. CBT teaches a person to modify beliefs or behaviors that may be leading to negative emotions.
While not a certainty, long‐term antipsychotic treatment is a very common outcome for people with schizophrenia.
Antipsychotic medications are the first-line medication treatment for schizophrenia. They have been shown in clinical trials to be effective in treating symptoms and behaviors associated with the disorder. However, antipsychotic medications have significant side effects.
Treatment of schizophrenia without medication is primarily with psychotherapy. Psychotherapy takes place in sessions with a clinical therapist who works with clients to help them manage and navigate reality and distortions in their thoughts.
Some common ones are: Chlorpromazine (Thorazine) Fluphenazine (Prolixin) Haloperidol (Haldol)
The exact causes of schizophrenia are unknown. Research suggests a combination of physical, genetic, psychological and environmental factors can make a person more likely to develop the condition. Some people may be prone to schizophrenia, and a stressful or emotional life event might trigger a psychotic episode.
The US Food and Drug Administration (FDA) has approved UZEDY, a new drug for the treatment of schizophrenia. Manufactured by Teva Pharmaceutical Industries, Ltd., UZEDY uses copolymer technology to slowly release the active ingredient, risperidone, over a period of one to two months.
The majority of people with schizophrenia get better over time, not worse. For every five people who develop schizophrenia: One will get better within five years of experiencing their first symptoms. Three will get better, but will still have times when their symptoms get worse.
You may only need antipsychotics until your acute schizophrenic episode has passed. However, most people take medication for 1 or 2 years after their first psychotic episode to prevent further acute schizophrenic episodes occurring, and for longer if the illness is recurrent.
Schizophrenia patients also have high rates of co-occurring disorders, like substance abuse and depression. These additional disorders can make the underlying schizophrenia more difficult to treat and it is possible schizophrenia may even be misdiagnosed due to the existence of the other disorders.
Atypical Antipsychotics
These medications, including quetiapine, risperidone, and aripiprazole, are generally prescribed because they pose a lower risk of certain serious side effects than conventional antipsychotics.
Most people with schizophrenia make a recovery, although many will experience the occasional return of symptoms (relapses). Support and treatment can help you to manage your condition and the impact it has on your life.
Antipsychotics (atypical & typical)
They're the first-line treatment and work on chemicals in the brain like dopamine and serotonin. Antipsychotics can reduce some common schizophrenia symptoms like hallucinations and delusions.