One of these cannabinoids, cannabigerolic acid (CBGA), is the “mother of all cannabinoids”, Associate Professor Arnold said, as it is the precursor molecule to the creation of better-known cannabinoids, like cannabidiol (CBD) and tetrahydrocannabinol (THC).
Cannabigerol (CBG) is a type of cannabinoid obtained from the cannabis plant. It's often referred to as the mother of all cannabinoids. This is because other cannabinoids are derived from cannabigerolic acid (CBGA), an acidic form of CBG.
CBGA, known as cannabigerolic acid, is considered the “mother cannabinoid,” because without it, there is no CBD, CBDA or THC. CBGA compounds are similar to other cannabinoids, but it hasn't been studied nearly as much as the others.
The two main cannabinoids are delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD).
THC-P. This brings us to the last and most potent psychoactive cannabinoid on the market. THC-P is derived from the hemp plant and also extracted similarly to Delta-8 THC, but it's wildly potent. THC-P is 30x stronger than Delta-9 THC, but some research indicates that it's actually 33x stronger.
CBN is a rare cannabinoid and, unlike THC, CBN is generally regarded as non-intoxicating. In this most recent study, researchers used synthetically produced CBN and tested it against a panel of various cannabinoids.
THC or Tetrahydrocannabinol is the major psychoactive component and one of the 113 cannabinoids recognized in cannabis.
The “Big Six” Cannabinoids
A majority of scientific research has focused on six phytocannabinoids in particular: CBD, THC, CBN, CBG, CBC, and THCV. These cannabinoids have earned the spotlight in research due to either their abundance in the cannabis plant or their sizable role in the impact of cannabis on the body.
THC, CBD, CBG, CBN and CBC: The Top Five Most Important Cannabinoids to Know.
So, while you could go out and purchase CBD products by themselves, studies show that THC and CBD work best in combination. Both cannabinoids have important medical benefits and may significantly improve a person's quality of life if they suffer from: Anxiety.
A 2013 study from scientists in Guelph, Canada, found that CBDA was a thousand times more powerful than CBD in binding to a specific serotonin receptor linked to anti-nausea and anti-anxiety effects when administered alongside low-doses of the traditional anti-nausea drug for chemotherapy patients, ondansetron (OND).
Like CBD, CBDa is non-intoxicating, meaning it won't get you high. And like CBD, CBDa is believed to have potential anti-inflammatory and anti-proliferative properties. Researchers are working on producing evidence that it serves to reduce anxiety, nausea, inflammation, vomiting, tumor proliferation, and more.
Both CBDA and CBD are non-psychotropic cannabinoids, so they will not produce that euphoric sensation attributed to THC. While CBDA's traits are similar to those found in CBD, CBDA has been shown to have greater bioavailability than CBD, meaning the body can absorb more of it.
Known as the “the mother of all cannabinoids,” cannabigerol (CBG) is a non-psychoactive derivative that breaks down to form other cannabinoids, CBD and tetrahydrocannabinol (THC) included.
It is a complex plant with about 426 chemical entities, of which more than 60 are cannabinoid compounds [Dewey, 1986]. The four major compounds are d-9-THC, CBD, d-8-THC and cannabinol, which have been most researched [Pertwee, 1997, 2008; Pamplona and Takahashi, 2012].
There are three main types of cannabinoids: phytocannabinoids, endocannabinoidannabin, and synthetic cannabinoids. Phytocoids are cannabinoids that come from plants, while endocannabinoids are cannabinoids that are produced by the human body. Synthetic cannabinoids are cannabinoids that are created in a lab.
Godfather OG is quite possibly the highest THC strain. Labs put the strain's THC levels at a tremendous 30-35%. In fact, Godfather OG is touted as the world's strongest marijuana strain. This potent strain is an Indica-dominant hybrid and hits within minutes of taking the first smoke.
Until recently, scientists had identified cannabinoids only in the Cannabis plant, commonly called marijuana or hemp. Current research, however, has found cannabinoids in many plants, including clove, black pepper, Echinacea, broccoli, ginseng, and carrots.
Full spectrum: Refers to marijuana products that maintain a variety of cannabinoids such as THC, CBD, CBG, CBN and more, versus products created with a single, isolated cannabinoid.
THE BIG THREE CBD < 30% The Big Three Pre-rolled is a selection of our best flowers. The pack contains 3 pre-rolled joints: Moonrock, Green Gelato and Harlequin. The Big Three Pre-rolled is a technical collector's item, ornament or ambient fragrance.
Cannabis extracts refers to a broad range of products that generally contain higher levels of cannabinoids than are found in the cannabis plant. Cannabinoids are chemical compounds found in cannabis that can affect your mind and body when consumed.
As of 2023, the highest THC strain is Godfather OG, reported to be the most potent strain in the world. A report claims that the Indica flower contains a THC concentration of 34%. Smoking Godfather OG will reportedly induce a head-based high which eventually turns into a euphoric whole-body feeling.
Cannabinoids have widespread actions in the brain: in the hippocampus they influence learning and memory; in the basal ganglia they modulate locomotor activity and reward pathways; in the hypothalamus they have a role in the control of appetite.
The psychoactive cannabinoid Δ9-THC and its precursor Δ9-tetrahydrocannabinolic acid A were found in all plant samples, with the highest concentration in the leaves and flower.