The "worst" type of depression is subjective, but Psychotic Depression (severe MDD with psychosis like hallucinations/delusions) and Treatment-Resistant Depression (TRD) are considered among the most severe due to high suicide risk, functional impairment, and difficulty treating, often requiring intensive interventions like ECT. Severe Major Depressive Disorder (MDD) itself, characterized by debilitating symptoms, also ranks high, as it can lead to profound inability to function and increased suicide risk.
Clinical depression is the more-severe form of depression, also known as major depression or major depressive disorder. It isn't the same as depression caused by a loss, such as the death of a loved one, or a medical condition, such as a thyroid disorder.
Differences found between major and minor depression included greater psychiatric distress and poorer psychosocial functioning in patients who met criteria for major depression.
The Danakil Depression is a large valley of approximately 200 by 50 km (124 by 31 mi), across the north of the Afar Region of Ethiopia and Eritrea. It is about 125 m (410 ft) below sea level and is bordered to the west by the Ethiopian Plateau and to the east by the Danakil Alps, beyond which is the Red Sea.
Here are the five key stages of depression.
The "3 Cs of Depression" usually refer to Catch, Check, Change, a core technique in Cognitive Behavioral Therapy (CBT) for challenging negative thought patterns (cognitive distortions) common in depression, helping you Catch the thought, Check its accuracy/helpfulness, and Change it into a more balanced one. Less commonly, it can refer to depressive symptoms like Crying spells, Concentration issues, and Cognitive/Emotional symptoms, but the CBT framework is the most recognized "3 Cs".
Here are 10 things that are often mistaken for depression, starting with one we see all the time in trauma work.
Clinical depression, or major depressive disorder, is often just called “depression.” It's the most severe type of depression. Without treatment, depression can get worse and last longer. In severe cases, it can lead to self-harm or death by suicide.
If you have 5 or more of these symptoms for at least 2 weeks, call your healthcare provider:
For many people, psychotherapy combined with medication works best. It can help identify underlying concerns that may be adding to your depression. In working with your therapist, you can also learn specific behaviors and strategies to overcome your depression.
Conclusions: Across the entire lifetime, every new episode of depression brings a new risk for mania; more than half of our severe mood disorder cases became bipolars. The risk of depression developing into bipolar disorder remains constant lifelong.
Severe depression is often characterized by symptoms of hopelessness, increased irritability, loss of pleasure, trouble concentrating or sleeping, or thoughts of death or suicide. 1 Technically, severe depression isn't a formal mental health diagnosis. Instead, it refers to more debilitating depression.
Psychological symptoms
If you think depression, schizophrenia, or bipolar disorder are the mental illnesses most commonly linked to an early death, you're wrong. Eating disorders—including anorexia nervosa, bulimia, and binge eating— are the most lethal mental health conditions, according to research in Current Psychiatry Reports.
New evidence shows that people who maintain a range of healthy habits, from good sleep to physical activity to strong social connections, are significantly less likely to experience depression.
Immediate hospitalization is essential for those who express suicidal ideation or have attempted self-harm. Severe Functional Impairment: Moreover, patients unable to care for themselves, including neglecting personal hygiene, nutrition, or medications, often require hospital-based treatment.
The symptoms vary from person to person and may depend upon the underlying cause. If you feel you are having a nervous breakdown you may: have anxiety or depression that you can't manage. withdraw from your usual daily activities, miss appointments or social activities.
Clinical depression is considered a disability under the ADA, but not everyone who suffers from it is protected. In general, the ADA is used on a case-by-case basis. Because no two people are the same, no two disabilities are either. There are many misconceptions about what depression is and how it affects people.
Depression also may lead to decreased volume in the hippocampus, the part of the brain involved in memory. “Research has shown that the number of days of untreated depression has a direct impact on hippocampal size,” she says.
Among the SSRIs paroxetine seems to be the worst offender and fluoxetine the least while sertraline and fluvoxamine tend to be intermediate. However, the most serious discontinuation reactions came from the SNRI venlafaxine.
It's thought that your chance of getting severe depression may be partly affected by the genes you inherit from your parents.
The most effective antidepressant compared to placebo was the tricyclic antidepressant amitriptyline, which increased the chances of treatment response more than two-fold (odds ratio [OR] 2.13, 95% credible interval [CrI] 1.89 to 2.41).
Overall, people diagnosed with depression were 2.41 times more likely to develop dementia than those not diagnosed with depression. That association held true even when the depression diagnoses occurred 20 years before the onset of dementia, and even when depression had been diagnosed in young adulthood.
Vitamin D may help improve mood and reduce symptoms of depression by lowering certain substances in the body that cause inflammation [16] Omega-3 fatty acids are also very important for helping to prevent depression. Omega-3 fatty acids, especially a type called n3-LCPUFAs, are found in large amounts in the brain.
Mania. Feeling manic is the opposite of feeling depressed.