What is the hallmark symptom of lupus?

skin rashes, especially a butterfly-shaped rash across the cheeks (this so-called malar rash is a hallmark of lupus) and rashes that develop on sun-exposed skin. brittle hair, or unusual hair loss. ulcers in the mouth or nose. fingers that turn white and/or blue from cold or stress (Raynaud's phenomenon)

Takedown request   |   View complete answer on childrenshospital.org

What is the hallmark indicator of lupus?

Common signs and symptoms of lupus

The most common lupus symptoms (which are the same for men and women) are: Extreme fatigue (feeling tired all the time) Pain or swelling in the joints. Swelling in the hands, feet, or around the eyes.

Takedown request   |   View complete answer on lupus.org

What is the classic symptom of lupus?

Constitutional manifestations

The general symptoms include: fever, malaise, arthralgias, myalgias, headache, and loss of appetite and weight. Nonspecific fatigue, fever, arthralgia, and weight changes are the most common symptoms in new cases or recurrent active SLE flares.

Takedown request   |   View complete answer on ncbi.nlm.nih.gov

What is the best indicator of lupus?

98% of all people with systemic lupus have a positive ANA test, making it the most sensitive diagnostic test for confirming diagnosis of the disease. The test for anti-nuclear antibodies is called the immunofluorescent antinuclear antibody test.

Takedown request   |   View complete answer on hopkinslupus.org

How does a doctor confirm lupus?

Your doctor will look for rashes and other signs that something is wrong. Blood and urine tests. The antinuclear antibody (ANA) test can show if your immune system is more likely to make the autoantibodies of lupus. Most people with lupus test positive for ANA.

Takedown request   |   View complete answer on cdc.gov

Systemic lupus erythematosus (SLE) - causes, symptoms, diagnosis & pathology

29 related questions found

When should you suspect lupus?

Signs can range from a mild rash and arthritis to kidney failure and seizures — “with a whole spectrum in between,” she says. Symptoms can also mimic other diseases, including infections and cancer.

Takedown request   |   View complete answer on everydayhealth.com

What can be mistaken for lupus?

As a result, people with lupus are frequently misdiagnosed with rheumatoid arthritis, fibromyalgia, chronic fatigue, skin disorders, psychological disorders such as anxiety and depression or receive no answers at all.

Takedown request   |   View complete answer on ncbi.nlm.nih.gov

What organ does lupus affect first?

Kidneys About one half of people with lupus experience kidney involvement, and the kidney has become the most extensively studied organ affected by lupus. Lungs About 50% of people with SLE will experience lung involvement during the course of their disease.

Takedown request   |   View complete answer on hopkinslupus.org

What does undiagnosed lupus look like?

A tell-tale sign of lupus is a butterfly-shaped rash across the cheeks and bridge of the nose. Other common skin problems include sensitivity to the sun with flaky, red spots or a scaly, purple rash on various parts of the body, including the face, neck, and arms. Some people also develop mouth sores.

Takedown request   |   View complete answer on webmd.com

What is the inflammatory marker for lupus?

C-reactive protein. CRP is the standard marker of inflammation, but in SLE patients, CRP is more of a marker for severe infections (Table 3). It is therefore of interest to analyze the role of CRP in SLE in some detail. CRP is directly driven by IL-6 [32], and IL-6 levels are increased in active SLE [33,34].

Takedown request   |   View complete answer on sciencedirect.com

Does lupus show up in blood tests?

And unlike other diseases, doctors can't diagnose it with a single lab test. But your doctor can look at your symptoms and family history and then use lab tests to confirm a diagnosis of lupus. Blood tests and other tests can also help monitor the disease and show the effects of treatment.

Takedown request   |   View complete answer on webmd.com

What are autoimmune markers for lupus?

Antinuclear antibodies (ANAs)

If you have a positive ANA test, it may mean you have an autoimmune disease. Autoimmune diseases cause your immune system to attack your healthy cells, tissues, or organs. Most people with lupus have ANA antibodies in their blood.

Takedown request   |   View complete answer on lupus.org

What are the early signs of lupus in females?

Common symptoms include fatigue, hair loss, sun sensitivity, painful and swollen joints, unexplained fever, skin rashes, and kidney problems. There is no one test for SLE. Usually, your doctor will ask you about your family and personal medical history and your symptoms. Your doctor will also do some laboratory tests.

Takedown request   |   View complete answer on cdc.gov

What disease has the same symptoms as lupus?

Common diseases that overlap with lupus:
  • Autoimmune thyroid disease.
  • Celiac disease.
  • Myasthenia gravis.
  • Antiphospholipid syndrome.
  • Rheumatoid arthritis.
  • Polymyositis.
  • Dermatomyositis.
  • Scleroderma.

Takedown request   |   View complete answer on lupus.org

How long can you have lupus without knowing?

Lupus is known as "the great imitator" because its symptoms mimic many other illnesses. Lupus symptoms can also be unclear, can come and go, and can change. On average, it takes nearly six years for people with lupus to be diagnosed, from the time they first notice their lupus symptoms.

Takedown request   |   View complete answer on lupus.org

What are three triggers of lupus?

Common triggers include:

Being out in the sun or having close exposure to fluorescent or halogen light. Infection. Injury. Stopping your lupus medicines.

Takedown request   |   View complete answer on cdc.gov

What part of the body hurts with lupus?

You may experience pain and stiffness, with or without swelling. This affects most people with lupus. Common areas for muscle pain and swelling include the neck, thighs, shoulders, and upper arms.

Takedown request   |   View complete answer on cdc.gov

What is the life expectancy with lupus?

The prognosis of lupus is better today than ever before. With close follow-up and treatment, 80-90% of people with lupus can expect to live a normal life span. It is true that medical science has not yet developed a method for curing lupus, and some people do die from the disease.

Takedown request   |   View complete answer on lupus.org

What looks like lupus but not?

Undifferentiated Connective Tissue Disease

“There are people who have a milder form of an autoimmune disease who just don't meet the classification criteria for lupus. We call that undifferentiated connective tissue disease (UCTD),” says Dr. Petri.

Takedown request   |   View complete answer on creakyjoints.org

Is it lupus or MS?

Lupus often causes skin rashes, arthritis, mouth sores, sun sensitivity, hair loss, or kidney problems, but these symptoms don't show up in MS. Even when lupus affects your nervous system, its most common symptoms are migraine, personality changes, seizures, or stroke, but these aren't typical for MS.

Takedown request   |   View complete answer on webmd.com

What does a mild case of lupus look like?

There are three types of cutaneous (skin) lupus. Each type has similar symptoms, including a red, scaly rash that often results from exposure to the sun. In this type of cutaneous lupus, the skin lesions are round (disk-shaped), thick, scaly and red. You may experience symptoms including pain, itching and burning.

Takedown request   |   View complete answer on my.clevelandclinic.org

What are the 4 criteria for lupus?

Lupus: Criteria for Diagnosis
  • Butterfly (malar) rash on cheeks.
  • Rash on face, arms, neck, torso (discoid rash)
  • Skin rashes that result from exposure to sunlight or ultraviolet light (photosensitivity)
  • Mouth or nasal sores (ulcers), usually painless.
  • Joint swelling, stiffness, pain involving two or more joints (arthritis)

Takedown request   |   View complete answer on myhealth.alberta.ca

How did you first know you had lupus?

I had high fevers, my mouth ulcers had taken on a life of their own, my taste buds were no longer functioning, and all I wanted to do was sleep. Finally, my rheumatologist diagnosed me with lupus.

Takedown request   |   View complete answer on lupus.org

What foods make lupus worse?

Saturated Fat and Trans Fat

Foods that contain saturated fat or trans fat also contain steroids that can contribute to weight gain because they increase your appetite. It is best to limit both as much as possible since being overweight or obese could worsen your lupus symptoms.

Takedown request   |   View complete answer on wvrheumatology.com