"In fibromyalgia, the misfiring and irregular engagement of different parts of the brain to process normal sensory stimuli like light, sound, pressure, temperature and odor, results in pain, flu-like sensations or other symptoms.
Fibromyalgia is a disorder characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory and mood issues. Researchers believe that fibromyalgia amplifies painful sensations by affecting the way your brain and spinal cord process painful and nonpainful signals.
Fibromyalgia is characterized by altered frontal and cerebellar structural covariance brain networks.
In people with fibromyalgia blood tests fail to show any serious abnormalities. CT and MRI scans looking for abnormalities affecting the brain, spinal cord or nerves are normal or inconsistent with the persons symptoms.
It's unlikely that you'll need an MRI for a diagnosis of fibromyalgia or chronic fatigue syndrome unless your particular set of symptoms is similar to that of a neurological illness that requires evaluation with an MRI. You may also need an MRI at some point to diagnose an injury or a different illness.
Many neurologists have an understanding of fibromyalgia, but like rheumatologists, they're not all familiar with it. The pain from fibromyalgia is what typically prompts people to visit a neurologist, and this specialist may prescribe medications to control your pain.
FACT: Fibromyalgia is a neurological disease affecting a person's sensory processing system. Fibromyalgia does not involve inflammation or damage to joints. Brain imaging and studies have shown that fibromyalgia is a disorder of the central nervous system.
As such, fibromyalgia is deemed to be one of the central sensitivity syndromes. There is increasing evidence of neurogenically derived inflammatory mechanisms occurring in the peripheral tissues, spinal cord and brain in fibromyalgia.
Key Differences Between MS and Fibromyalgia
MS is an autoimmune disease caused by a problem within the immune system that causes damage to the layer covering the nerves. Fibromyalgia is thought to be caused by abnormal levels of chemicals in the brain.
One of the main theories is that people with fibromyalgia have developed changes in the way the central nervous system processes the pain messages carried around the body. This could be the result of changes to chemicals in the nervous system.
FMS patients also show problems in cognitive performance, especially in planning, attention, memory, executive functions, and processing speed. There is also evidence of high levels of negative affect, neuroticism, perfectionism, stress, anger, and alexithymia in FMS patients.
a) is a condition that causes pain all over the body (also referred to as widespread pain), sleep problems, fatigue, and often emotional and mental distress. People with fibromyalgia may be more sensitive to pain than people without fibromyalgia. This is called abnormal pain perception processing.
Several rheumatic diseases can mimic fibromyalgia. These include sero-negative rheumatoid arthritis, ankylosing spondylitis, Lyme disease, polymyalgia rheumatica and lupus. They have symptoms of widespread pain along with joint involvement. Most rheumatic diseases are treated with medication and physical therapy.
Researchers concluded that fibrofog was not associated with progressive cognitive decline and did not support the idea that there is a transition over time from the memory loss to Alzheimer's disease.
Other researchers believe fibromyalgia is caused by a lack of deep sleep. It is during stage 4 sleep that muscles recover from the prior day's activity, and the body refreshes itself. Sleep studies show that as people with fibromyalgia enter stage 4 sleep, they become more aroused and stay in a lighter form of sleep.
The FM/a ® Test analyzes your immune system's white blood cells for their chemokine and cytokine protein patterns. Those who suffer from fibromyalgia will show an abnormal pattern of these protective proteins.
The drugs amitriptyline, duloxetine, milnacipran and pregabalin can relieve fibromyalgia pain in some people. They may cause side effects such as a dry mouth or nausea. Normal painkillers like ibuprofen or acetaminophen (paracetamol) aren't recommended for the treatment of fibromyalgia.
Some people with fibromyalgia and myalgic encephalomyelitis /chronic fatigue syndrome (ME/CFS) use mobility aids such as canes, wheelchairs, scooters, and motorized grocery carts.
Researchers found that fibromyalgia, a condition involving widespread musculoskeletal pain, was more than three times as common in people who were later diagnosed with MS.
In fibromyalgia, research shows that glutamate levels are too high in relation to GABA, which can lead to overstimulation and affect chronic pain. 5. Cortisol levels (low): Deficiencies in the stress hormone cortisol, released when your body is under stress, may contribute to fibromyalgia.
The exact cause of fibromyalgia is unknown, but it's thought to be related to abnormal levels of certain chemicals in the brain and changes in the way the central nervous system (the brain, spinal cord and nerves) processes pain messages carried around the body.
As many fibromyalgia patients experience some form of stress or anxiety with their symptoms, this is thought to trigger headaches, particularly tension headaches. Poor sleep may also result in headaches.
But research has since shown that there are no abnormalities in the musculoskeletal system in people with fibromyalgia. Instead, the problem appears to lie in the pain processing pathways of our central nervous system—the bailiwick of neurologists. Today, both rheumatologists and neurologists treat fibromyalgia.
Unfortunately, fibromyalgia is still a somewhat controversial diagnosis, because it is not yet fully understood and its symptoms can overlap with many other conditions. Some people even say that it's a “garbage can” diagnosis that's only given when no other one can be made.
Because fibromyalgia presents as a cluster of nebulous (vague) symptoms, and there is no definitive cure, treatments are based on trial and error. This can be tremendously frustrating to physicians and that means patients have to cope with the fallout.