Antimuscarinic therapy -- with or without behavioural therapy -- represents the most common treatment for patients with OAB. Several antimuscarinic agents are currently available for the treatment of OAB in adults, including oxybutynin, tolterodine, trospium chloride, darifenacin and solifenacin.
The best OAB medications available are anticholinergics and beta-3 adrenergic agonists. Be sure to ask your healthcare provider if it's safe to take them with your other potential medications and health conditions.
Changing your lifestyle may help with bladder problems. Losing weight, quitting smoking, saying “no” to alcohol, choosing water instead of other drinks, and limiting drinks before bedtime can help with some bladder problems. Preventing constipation and avoiding lifting heavy objects may also help with incontinence.
Medications that relax the bladder can be helpful for relieving symptoms of overactive bladder and reducing episodes of urge incontinence. These drugs include: Tolterodine (Detrol) Oxybutynin, which can be taken as a pill (Ditropan XL) or used as a skin patch (Oxytrol) or gel (Gelnique)
Vitamin C found in foods.
A study done on vitamin c intake in 2060 women, aged 30-79 years of age found that high-dose intake of vitamin c and calcium were positively associated with urinary storage or incontinence, whereas vitamin C from foods and beverages were associated with decreased urinary urgency.
As far as bladder medications are concerned, immediate release oxybutynin has been shown to adversely affect cognition in the cognitively intact elderly.
Overactive bladder is a collection of symptoms that may affect how often you pee and your urgency. Causes include abdominal trauma, infection, nerve damage, medications and certain fluids. Treatment includes changing certain behaviors, medications and nerve stimulation.
Reasons for loss of bladder control:
Overactive bladder muscles. Blockage from an enlarged prostate. Medication interactions. Damage to nerves that control the bladder from diseases such as multiple sclerosis or Parkinson's disease.
The drug oxybutynin may be used to treat OAB. It is available over-the-counter in patch form, which delivers 3.9 mg of oxybutynin daily through your skin. However, the over-the-counter patch is only available to women. Men may take oxybutynin in patch or oral form, but they need a prescription for it.
While it's not uncommon for people over 60 to urinate once or twice a night, if you urinate more than twice a night you should consider consulting a doctor.
One study found that pumpkin seed oil improves abnormal urinary function and reduces symptoms of OAB. Another Japanese study found that pumpkin seeds and soybean seed extract also significantly reduced incontinence.
Mirabegron works by relaxing the muscles around your bladder. This means your bladder can hold more liquid and reduces your need to pee as often or as urgently. This medicine is only available on prescription. It comes as slow-release tablets (called "modified release" or "prolonged release").
The drug desmopressin (DDAVP) reduces urine production at night.
The bladder antimuscarinics evaluated in this study were oxybutynin, solifenacin, tolterodine, propiverine, trospium, darifenacin, and fesoterodine. Patients using these medications exhibited a 2.46-fold increased risk of dementia compared to non-users (95%CI: 2.22–2.73) (15).
Those taking oxybutynin 5mg per day or doxepin hydrochloride 10 mg per day (tricyclic antidepressant), for more than three years had the greatest risk of dementia. Those taking an anticholinergic primarily in the past had a risk of dementia similar to those with recent or continued use.
However, oxybutynin extended-release tablet is not recommended in children who cannot swallow it whole without breaking, chewing, or crushing; or in children younger than 6 years of age.
Caffeine, artificial sweeteners, alcohol, chocolate and very spicy foods may make OAB symptoms worse. OAB does not cause pain. If you feel pain while urinating, you may have an infection . Please talk with your health care provider about pain.
Because the bladder can only hold so much fluid volume, increasing water intake will increase the frequency of urination, and may make people with an overactive bladder more likely to leak. If you have overactive bladder (OAB), more fluid intake typically equals more trips to the bathroom.
Magnesium. Magnesium is important for proper muscle and nerve function. Some doctors believe better magnesium levels can reduce bladder spasms, a common cause of incontinence.
While we mentioned above some beverages that irritate your bladder, there are also some things you can drink to try to help soothe your bladders, such as plain water, milk, and no-sugar-added cranberry juice. They're also foods you can eat to soothe your bladder and keep it at its healthiest.
Some research shows that magnesium hydroxide can reduce spontaneous muscle contractions that cause incontinence. A small study found that magnesium hydroxide improved urinary incontinence in women. But there were also side effects of vomiting, diarrhea, and cramping.