When your liver starts dying (liver failure), it can't filter toxins, produce proteins, or help with digestion, leading to severe fatigue, confusion, jaundice (yellow skin/eyes), fluid buildup (swollen belly/legs), easy bruising/bleeding, and digestive issues, with symptoms worsening as the liver fails, requiring urgent medical help.
The final days of liver failure can vary, depending on the person. Someone may experience symptoms such as yellow skin and eyes, confusion, swelling, and general or localized pain. The symptoms of end-stage liver disease typically worsen as the patient becomes closer to death.
Symptoms
Your liver can keep working even if part of it is damaged or removed. But if it starts to shut down completely—a condition known as liver failure—you can survive for only a day or 2 unless you get emergency treatment. Many things can affect liver function.
Lifestyle and home remedies
Cirrhosis of the liver is a severe condition, causing scarring and permanent damage to the liver. Life expectancy depends on the stage and type of liver cirrhosis, but it may vary between roughly 2 to 12 years. The liver is the second largest organ in the human body and one of the most important for human health.
Four key warning signs of a damaged liver include jaundice (yellow skin/eyes), abdominal issues (swelling, pain), fatigue/weakness, and changes in urine/stool color, alongside symptoms like itchy skin, easy bruising, confusion, or nausea, indicating the liver isn't filtering toxins or clotting blood properly.
A failing liver cannot remove toxins from the blood, and they eventually accumulate in the brain. The buildup of toxins in the brain-called hepatic encephalopathy-can decrease mental function and cause coma.
The three worst things for your liver are excessive alcohol, a diet high in added sugars, unhealthy fats, and salt (processed/fast foods), and overuse of certain medications (like acetaminophen/paracetamol), all leading to fat buildup (fatty liver), inflammation, and potential severe damage like cirrhosis, though lifestyle changes can often reverse early stages.
At first, acute liver failure causes fatigue, nausea, loss of appetite, discomfort on your right side just below your ribs, and diarrhea. As it gets worse, your skin may turn yellow, and you may become confused or comatose. Acute liver failure is a serious condition. It requires medical care right away.
The first symptoms of chronic or acute liver failure may include: Abdominal pain (especially in the upper right). Fatigue and malaise (feeling unwell). Nausea, vomiting and loss of appetite.
Fetor hepaticus is a distinct smell on the breath of someone with liver disease. It happens when your liver can't filter certain toxic substances from your blood anymore. These substances build up in your blood and come out in your breath. You may also detect the same smell in your pee or sweat.
As the liver becomes more severely damaged, more obvious and serious symptoms can develop, such as: yellowing of the skin or whites of the eyes (jaundice) swelling in the legs, ankles and feet caused by a build-up of fluid (oedema)
You can't live without a working liver. If your liver stops working correctly, you may need a transplant. A liver transplant may be advised if you have end-stage liver disease (chronic liver failure).
Some liver and kidney disorders and some urinary tract infections can turn urine dark brown. So can bleeding inside the body called a hemorrhage. A group of illnesses that mainly affect the skin or the nervous system, called porphyria, also can cause brown urine.
Pain relievers such as acetaminophen, aspirin, ibuprofen (Advil, Motrin IB, others) and naproxen sodium (Aleve) can damage the liver. Taking them often or with alcohol can cause more damage. Prescription medicines.
Alcohol is perhaps the most well-known cause of liver damage. When you drink, your liver works to break down the alcohol and clear it from your system. But too much alcohol overwhelms this process, causing toxic by products to build up and damage liver cells. Alcohol-related liver disease progresses in stages.
For liver repair and support, focus on hydration with water, green tea, and coffee, plus juices from blueberries, cranberries, grapefruit, or beetroot, all rich in antioxidants that fight damage and inflammation, but avoid alcohol and sugary drinks that stress the liver.
Liver pain is typically felt in the upper right abdomen, just under the rib cage, but it can also radiate to the right shoulder blade, back, or even the center of the chest, sometimes described as dull or aching, and can signal issues like fatty liver, inflammation, or more serious disease.
14 signs of liver damage
Liver Failure Symptoms
Jaundice, or yellow eyes and skin. Confusion or other thinking difficulties. Swelling in the belly, arms or legs. Severe fatigue.
How do you check your liver health?
Someone with liver failure who is nearing death is described as having end-stage liver disease. This can cause symptoms such as jaundice, confusion and uncertainty, severe tiredness, a build-up of fluid in the abdomen, shortness of breath, and bleeding easily.
Early symptoms can include:
The liver is located in the upper right-hand portion of the abdominal cavity, beneath the diaphragm, and on top of the stomach, right kidney, and intestines. Shaped like a cone, the liver is a dark reddish-brown organ that weighs about 3 pounds.