Taking omeprazole for more than a year may increase your chances of certain side effects, including: bone fractures. gut infections. vitamin B12 deficiency – symptoms include feeling very tired, a sore and red tongue, mouth ulcers and pins and needles.
Prolonged use can also reduce the absorption of magnesium and B12, and increase the risk of intestinal infections, such as those caused by Clostridium difficile, leading to severe diarrhea.
Omeprazole tablets that you buy from pharmacies or supermarkets can be taken by adults for up to 14 days.
Omeprazole can raise your risk for a bacterial infection with Clostridium difficile (C. diff). This bacterial infection can cause severe diarrhea. C. diff infections from omeprazole are linked to long-term use. This is why it's recommended to use the lowest possible dose of omeprazole for the shortest time needed.
Despite their wide use, omeprazole and esomeprazole have only rarely been associated with hepatic injury. In large scale, long term trials , serum ALT elevations occurred in less than 1% of patients and at rates similar to those that occurred with placebo or comparator drugs.
Omeprazole is a proton pump inhibitor (PPI). It works by decreasing the amount of acid produced by the stomach. This medicine is available both over-the-counter (OTC) and with your doctor's prescription.
PPIs like omeprazole have been associated with acute kidney injury (AKI). AKI is a sudden worsening of kidney function. Even though it's often reversible, it can be dangerous. AKI can cause a build-up of waste products in the body, and affect other organs like the brain and heart.
Taking omeprazole for more than a year may increase your chances of certain side effects, including: bone fractures. gut infections. vitamin B12 deficiency – symptoms include feeling very tired, a sore and red tongue, mouth ulcers and pins and needles.
Stopping PPI treatment can cause rebound acid hypersecretion, leading to the transient appearance of symptoms such as indigestion, heartburn or regurgitation.
Taking omeprazole for more than a year may increase your chances of certain side effects, including: bone fractures. gut infections. vitamin B12 deficiency – symptoms include feeling very tired, a sore and red tongue, mouth ulcers and pins and needles.
You shouldn't take OTC omeprazole for longer than 14 days without a healthcare provider's OK. Prescription omeprazole is often taken for 4 to 8 weeks, depending on what you're treating. For some conditions, it's taken for even longer. Taking omeprazole for too long can lead to serious side effects.
Tolerance and safety were good and comparable in both groups. Conclusion Gaviscon® was non-inferior to omeprazole in achieving a 24-h heartburn-free period in moderate episodic heartburn, and is a relevant effective alternative treatment in moderate GERD in primary care.
PPIs have been reported to cause weight gain. That being said, weight gain isn't a common side effect. It also seems to be more likely when you take PPIs long term. One study found that long-term use of omeprazole, rabeprazole, or lansoprazole was associated with weight gain.
A new analysis of the FDA adverse events database (FAERS) has reported that use of proton pump inhibitors (e.g. omeprazole, rabeprazole, lansoprazole, pantoprazole) may be associated with a risk of neurological conditions, including hearing and visual impairment, memory loss, neuropathy and migraine (Sci Rep 2019;9: ...
Is Nexium more effective than omeprazole? Nexium was shown by some clinical trials to provide faster acid reflux relief and to provide fewer nights with GERD symptoms. However, in the longer term view of the study, both medications performed similarly.
Another analysis of several studies found that esomeprazole 40 mg was more effective than omeprazole at treating esophagitis (inflammation of the esophagus) due to GERD after 8 weeks of treatment.
Food Tips when taking Omeprazole:
Greasy or fatty foods like french fries, pizza, deep fried chicken slow the digestive system down and often causes indigestion, heartburn and nausea. Onions, garlic, chocolate, coffee, peppermint and some spices can also cause an increase in gastric symptoms.
When omeprazole is stopped, a common side effect is rebound acid secretion, where the acid secretion in your stomach increases significantly. This should return to normal within 2 weeks.
A large study found that stroke patients taking proton pump inhibitors (PPIs) like omeprazole were more likely to develop osteoporosis and hip or spinal fractures (Osteoporosis International, Jan.
Official answer. Omeprazole (Prilosec) is a proton pump inhibitor (PPI) that is used to reduce the amount of acid in your stomach and it can be bad for your kidneys. It can cause acute kidney injury and may also worsen the progression of chronic kidney disease (CKD).
There is some evidence that omeprazole or esomeprazole may prevent clopidogrel from working as effectively, leading to more heart attacks among people who took both drugs. This evidence is limited, though, and some trials have suggested there may not be an issue. If you have concerns, speak to your doctor.
Omeprazole interferes with the absorption of vitamin B12 from food (though not from supplements) in some but not all studies. A true deficiency state, resulting in vitamin B12-deficiency anemia, has only been reported in one case.