If the underlying cause of peripheral neuropathy isn't treated, you may be at risk of developing potentially serious complications, such as a foot ulcer that becomes infected. This can lead to gangrene (tissue death) if untreated, and in severe cases may mean the affected foot has to be amputated.
Stage 5: Complete Loss of Feeling
This is the final stage of neuropathy, and it is where you've lost any and all feeling in your lower legs and feet. You do not feel any pain, just intense numbness. This is because there are no nerves that are able to send signals to your brain.
Nerve deterioration from peripheral neuropathy weakens the connected muscles. That can cause paralysis, which may cause difficulty moving the toes, foot drop and hand weakness. Weakness can also affect muscles in the thighs, arms and elsewhere. Muscle atrophy.
Acute Symmetrical Peripheral Neuropathy Rare, this severe, rapidly developing form of polyneuropathy affects nerves throughout the body and is most often seen in Guillain-Barré syndrome, an autoimmune disorder that attacks the peripheral nervous system and can be fatal.
Gradual onset of numbness, prickling or tingling in your feet or hands, which can spread upward into your legs and arms. Sharp, jabbing, throbbing or burning pain. Extreme sensitivity to touch.
The main medicines recommended for neuropathic pain include: amitriptyline – also used for treatment of headaches and depression. duloxetine – also used for treatment of bladder problems and depression. pregabalin and gabapentin – also used to treat epilepsy, headaches or anxiety.
Nutritional or vitamin imbalances, alcoholism, and exposure to toxins can damage nerves and cause neuropathy. Vitamin B12 deficiency and excess vitamin B6 are the best known vitamin-related causes.
With neuropathy, your symptoms may range from mild to severe and debilitating. Dr. Levine advises patients to see their doctors as soon as possible if they experience neuropathy's motor symptoms, which include muscle weakness, muscle wasting or uncontrolled twitching.
Peripheral neuropathy can cause pain and make it difficult to walk or do things with your hands.
With sensory peripheral neuropathy, nerve damage in the feet causes numbness, often as a result of diabetes or chemotherapy, leading to difficulties walking and a higher risk for falls.
Roughly 20 million Americans are living with neuropathy. Living with daily pain and discomfort can be challenging. People with neuropathy are at a higher risk for depression and anxiety than those without a neurological disorder. The good news is treatable, and a pain management specialist can help.
Unchecked neuropathy-related wounds “can become infected because they are open wounds, which can also progress into bone infection,” as well as gangrene, a potentially life-threatening issue caused by the death of wounded tissue, says Dr. Villani.
Neuropathy can affect nerves that control muscle movement (motor nerves) and those that detect sensations such as coldness or pain (sensory nerves). In some cases, it can affect internal organs, such as the heart, blood vessels, bladder, or intestines.
Peripheral neuropathy is common in US adults and is associated with an increased risk of death, even in the absence of diabetes, researchers report today in the Annals of Internal Medicine.
The most common type of neuropathy is peripheral neuropathy. It affects the nerves in the hands, feet, legs, and arms. It generally starts in the feet, and it tends to start in both feet at once.
Over time, those fibers may undergo degeneration and die, which means the neuropathy is worse because of the loss of more nerve fibers.
In acute neuropathies, such as Guillain-Barré syndrome, symptoms appear suddenly, progress rapidly, and resolve slowly as damaged nerves heal. In chronic forms, symptoms begin subtly and progress slowly.
Peripheral neuropathy is the most common, impacting 7 in 10 diabetics, among others. PN is often mistaken for another common illness, multiple sclerosis (MS).
Drink lots of water
Water should be a staple in any diet, and even more so for those looking to reduce nerve pain. It's critical to stay hydrated throughout the day to reduce inflammation and avoid triggering pain receptors. Aim to drink eight 8-oz. of water each day.
Sensory neuropathy affects these groups of nerves. Autonomic nerve neuropathy. Autonomic nerves control functions that you are not conscious of, such as breathing and heartbeat. Damage to these nerves can be serious.
Vitamins B-1, B-6, and B-12 have been found to be especially beneficial for treating neuropathy. Vitamin B-1, also known as thiamine, helps to reduce pain and inflammation and vitamin B-6 preserves the covering on nerve endings.
Intraneural Facilitation (INF) treatment effectively restores blood flow to damaged nerves, decreasing pain caused by diabetic peripheral neuropathy (DPN), according to a new study conducted by researchers at Loma Linda University Health.