About 15 to 25 percent of people with vitiligo are also affected by at least one other autoimmune disorder, particularly autoimmune thyroid disease, rheumatoid arthritis, type 1 diabetes, psoriasis , pernicious anemia, Addison disease, systemic lupus erythematosus, celiac disease, Crohn disease, or ulcerative colitis.
Vitiligo is associated with other autoimmune diseases: Addison disease (disorder that occurs when the adrenal glands do not produce enough hormones) Thyroid disease. Pernicious anemia (decrease in red blood cells that occurs when the intestines cannot properly absorb vitamin B12)
Vitiligo is an autoimmune disease of the skin, which means that someone with vitiligo has an immune system that is malfunctioning in a small way. The normal role of the immune system is to protect you from infections and cancer.
If you see white patches and spots on your skin, it's important to find out if you have vitiligo. This disease increases the risk of having some other autoimmune diseases like thyroid disease and alopecia areata. Some people develop hearing loss or a problem with their vision.
Vitiligo is a chronic (long-lasting) autoimmune disorder that causes patches of skin to lose pigment or color. This happens when melanocytes – skin cells that make pigment – are attacked and destroyed, causing the skin to turn a milky-white color.
Vitiligo is an under-recognized organ-specific autoimmune disease of the skin that results from cytotoxic T cell-mediated attack on melanocytes, the pigment-producing cells in the epidermis (18). The result is the loss of pigment in the skin, visible as white spots (Fig.
Vitiligo is associated with several comorbid autoimmune, systemic, and dermatological diseases, primarily thyroid disease, alopecia areata, diabetes mellitus, pernicious anemia, systemic lupus erythematosus, rheumatoid arthritis, Addison's disease, inflammatory bowel disease, Sjögren's syndrome, dermatomyositis, ...
As non-segmental vitiligo is closely associated with other autoimmune conditions, you may be assessed to see whether you have any symptoms that could suggest an autoimmune condition, such as: being tired and lacking energy, which may be a sign of Addison's disease.
In summary, these observations make it pretty clear that vitiligo is an autoimmune disease that is initiated by melanocyte stress, which can be worsened by exposure to chemicals. Genes, inherited from your parents, influence all of these pieces.
Nevertheless, vitiligo has been found to be associated with chronic hepatitis C virus (HCV) infection and autoimmune hepatitis [17].
Vitiligo does not pose a serious threat to one's health, but it can result in physical complications, such as eye issues, hearing problems, and sunburn. People with vitiligo also tend to be more likely to have another autoimmune disease (like thyroid disorders and some types of anemia).
A 10-year retrospective study involving 3,280 patients showed that comorbid autoimmune conditions occur in approximately 23% of vitiligo patients, including thyroid disease (TD), rheumatoid arthritis (RA), inflammatory bowel disease (IBD), systemic lupus erythematosus (SLE), and type 1 diabetes mellitus (35).
A 2016 study found that 20% of participants with vitiligo had an autoimmune disease. The most common of these was thyroid disease, at 12.9%. The reverse is also true – in a 2009 study, vitiligo was significantly more common in people with a thyroid disease than a control group.
The most noticeable symptom is a rapid loss of vision. There may also be neurological signs such as severe headache, vertigo, nausea, and drowsiness. Loss of hearing, and loss of hair (alopecia) and skin color may occur along, with whitening (loss of pigmentation) of the hair and eyelashes (poliosis).
In this study, vitiligo did not appear to be associated with a high body mass index, in contrast to most other autoimmune diseases.
For every 100,000 person-years, 503 people with vitiligo developed dementia compared to just 102 healthy controls.
medwireNews: Patients with the autoimmune disorder vitiligo have a “markedly reduced” risk for developing malignancies of internal organs compared with other individuals, Korean researchers report.
The one significant observation that we found to have the poor prognostic implication in vitiligo is the presence of mucosal vitiligo.
Vitiligo and Vitamins
To treat vitiligo, doctors generally prescribe vitamins, such as vitamins C, E, B12, D, and folic acid, in combination with other treatment regimens.
Here, we hypothesize that patients with non‐segmental vitiligo (NSV), an autoimmune skin (and mucosal) disorder, may clear SARS‐CoV‐2 infection more efficiently and have a lower risk of COVID‐19 development.
Vitiligo is an idiopathic disorder of skin and hair characterized by melanin loss. Nonetheless thyroid disorder is a major cause of this pathology, other factors participate in its expression. Hormones such as, testosterone and estrogen have been suspected as drivers of this disorder.
Vitiligo is a depigmenting autoimmune disease. Recent studies suggest a subset of vitiligo patients, those with more chronic and severe diseases, are at higher risk of developing dyslipidemia and atherosclerosis, with the potential increase of CVR.
The association of autoimmune hepatitis with vitiligo is well known, with a particular striking association with type 2 autoimmune hepatitis, a condition occurring almost entirely in children and adolescents, much rarer and more aggressive than type 1 autoimmune hepatitis; probable associations are also identified with ...
Vitiligo causes isolation, stigmatization, loss of self-esteem, depression, and self-consciousness.