Lupus nephritis occurs when lupus autoantibodies affect structures in your kidneys that filter out waste. This causes kidney inflammation and may lead to blood in the urine, protein in the urine, high blood pressure, impaired kidney function or even kidney failure.
Autoimmune diseases cause your immune system to attack your healthy cells. Lupus can affect many parts of the body. When your immune system attacks your kidneys, it is called lupus nephritis. The most severe kind of lupus nephritis is proliferative nephritis, which can cause permanent damage to your kidneys.
Scientists think that IgA nephropathy is an autoimmune kidney disease, meaning that the disease is due to the body's immune system attacking tissues in the kidney. IgA nephropathy is one of the most common kidney diseases, other than those caused by diabetes or high blood pressure.
The symptoms of lupus nephritis may include foamy urine and edema—swelling that occurs when your body has too much fluid, usually in the legs, feet, or ankles, and less often in the hands or face. You may also develop high blood pressure. Check your blood pressure. High blood pressure can be a sign of lupus nephritis.
The life expectancy of lupus nephritis depends on the severity of the symptoms and immune response to medications. With proper treatment, maintaining a healthy lifestyle and regular follow-ups, 80 to 90 percent of people with lupus nephritis are expected to live for the average lifespan.
Treatments include medicine that calms down the immune system and a blood-cleaning therapy (called plasmapheresis) to remove the autoantibodies. In this rare disease, irritation and swelling of the blood vessels (vasculitis) damages different organs in the body.
Cystinosis is a rare disorder that allows a natural chemical called cystine to build up in your body and cause health problems. Kidney damage from cystinosis can cause kidney failure. People with cystinosis must take medicine to lower their cystine levels and may need a kidney transplant.
Overview. Amyloidosis (am-uh-loi-DO-sis) is a rare disease that occurs when a protein called amyloid builds up in organs. This amyloid buildup can make the organs not work properly. Organs that may be affected include the heart, kidneys, liver, spleen, nervous system and digestive tract.
Common symptoms include fatigue, hair loss, sun sensitivity, painful and swollen joints, unexplained fever, skin rashes, and kidney problems. There is no one test for SLE. Usually, your doctor will ask you about your family and personal medical history and your symptoms. Your doctor will also do some laboratory tests.
Lupus is an autoimmune disease that triggers your immune system to attack your tissues. In addition to your kidneys, lupus can damage your brain, heart, joints, skin and other parts of your body. Lupus nephritis prevents your kidneys from: Controlling blood pressure and blood volume.
Autoimmune hepatitis (AIH) can affect both children and adults and can lead to cirrhosis and acute liver failure. It is often asymptomatic, with no symptoms prior to liver failure. It may also be associated with nonspecific symptoms including fatigue, nausea, abdominal pains, or joint pains.
There's no cure for lupus nephritis. Treatment aims to: Reduce symptoms or make symptoms disappear (remission) Keep the disease from getting worse.
The good news is that acute kidney failure can often be reversed. The kidneys usually start working again within several weeks to months after the underlying cause has been treated. Dialysis is needed until then.
You're more tired, have less energy or are having trouble concentrating. A severe decrease in kidney function can lead to a buildup of toxins and impurities in the blood. This can cause people to feel tired, weak and can make it hard to concentrate.
Some of the most common kidney pain symptoms include: A constant, dull ache in your back. Pain in your sides, under your rib cage or in your abdomen. Severe or sharp pain that comes in waves.
Most patients with SLE develop lupus nephritis early in their disease course. SLE is more common among women in the third decade of life, and lupus nephritis typically occurs in patients aged 20-40 years.
When your kidneys are failing, a high concentration and accumulation of substances lead to brown, red, or purple urine. Studies suggest the urine color is due to abnormal protein or sugar as well as high numbers of cellular casts and red and white blood cells.
Kidneys About one half of people with lupus experience kidney involvement, and the kidney has become the most extensively studied organ affected by lupus.