Ankylosing spondylitis (AS) significantly impacts mental health, leading to high rates of depression, anxiety, and sleep disturbances, driven by chronic pain, fatigue, and restricted mobility, which reduce quality of life and self-control, creating a negative cycle where psychological distress worsens AS symptoms. Other issues include somatization, anger, and low self-esteem, highlighting the need for comprehensive care addressing both physical and mental aspects.
IV infusion for ankylosing spondylitis involves administering medication through an infusion pump that drips the medication into a catheter to a syringe and through a hollow needle into the patient's bloodstream. IV infusion therapy options for ankylosing spondylitis include Simponi Aria and Remicade.
Omega-3 Fatty Acids
Studies have shown these nutrients help control symptoms in people with rheumatic diseases, including ankylosing spondylitis and rheumatoid arthritis. Omega-3 fatty acids are necessary for muscle activity, cell growth, and other body functions.
Ankylosing spondylitis is a systemic disease, meaning it can affect the entire body in some people. It can cause fever, loss of appetite, and fatigue, and it can damage other organs besides the joints, such as the lungs, heart, and eyes. Most often though, only the low back is involved.
Monoclonal antibodies, such as secukinumab and ixekizumab, may be offered to people with AS who do not respond to NSAIDs or anti-TNF medicine, or as an alternative to anti-TNF medicine. This type of treatment works by blocking the effects of a protein involved in triggering inflammation.
For long-term treatment, biologics are generally considered safer than prolonged steroid use. While steroids work quickly to reduce inflammation, they can cause serious side effects when used long-term, including: Bone loss and increased fracture risk. Weight gain and swelling.
The PAN: Ankylosing Spondylitis (Medicare) program offers essential support by covering a wide range of medications including Cimzia, Cosentyx, Enbrel, and Humira, among others, for patients diagnosed with ankylosing spondylitis.
[Conclusion] Affective temperament may contribute to symptoms of depression and anxiety in patients with Ankylosing Spondylitis and may increase disease activity and may reduce their quality of life.
July 18, 2025
A new peer-reviewed study published in Arthritis & Rheumatology suggests that ivarmacitinib, a new medication known as a selective JAK1 inhibitor, may be a promising treatment for people with active ankylosing spondylitis (AS). The study was a randomized, double-blind clinical trial.
Neurological complications and symptoms of ankylosing spondylitis
Chinese herbal medicine is a commonly used traditional treatment for ankylosing spondylitis (AS). Among them, Yanghe decoction (YHD) has an obvious effect in relieving the symptoms of AS, but its efficacy is still controversial.
For instance, he says, “It's been shown that vitamin D deficiency needs to be treated in lupus patients, but the effects are less clear when it comes to patients with rheumatoid arthritis.” Supplementing vitamin D won't cure an autoimmune disease, nor will it provide significant relief from its symptoms.
Vitamin C and Collagen
Vitamin C plays a key role in producing collagen, which keeps spinal discs and connective tissues strong. Excellent sources include citrus fruits, berries, and bell peppers.
Some patients may feel an improvement in symptoms as soon as the first week of starting golimumab. Typically, up to 6 weeks is required to see a benefit. Golimumab works for most patients. The medication may stop working in up to 10% (1 in 10) of patients every year.
A single prefilled syringe (50 mg) can cost approximately ₹12,000 to ₹30,000. Monthly Cost: Since most patients require four doses per month, the cumulative cost can range from ₹48,000 to ₹80,000 per month.
The therapy that was used to treat this disease previously could only alleviate the symptoms of inflammation. A new drug, i.e. seniprutug, was developed by the biotechnological company "BIOCAD" together with a group of scientists from the Pirogov Russian National Research Medical University.
Illness and death
According to his father, Biden was diagnosed with ankylosing spondylitis in 2001 after returning from service in Kosovo.
Prescriptions for your biologic/biosimilar medication come from your dermatology consultant, not your GP. It is important if you are asked to give a copy of your prescription list that you remember to add on your biologic/biosimilar medication.
HUMIRA Dosing for Ankylosing Spondylitis
The recommended dose is 40 mg every other week. Always follow your doctor's instructions about when and how often to take HUMIRA. HUMIRA is given by an injection under the skin. Your first dose of HUMIRA must be given under the supervision of a health care professional.
In an earlier study HLA-B27 was found to correlate with some subgroups of schizophrenia, having an increased incidence specially in the subgroup of patients with poor prognostic features.
You may experience the following with brain fog: Difficulty concentrating or focusing. Confusion. Fatigue.
Ankylosing Spondylitis (AS): HUMIRA is indicated for reducing signs and symptoms in adult patients with active ankylosing spondylitis.
Medicare may cover cortisone injections as frequently as a person requires them if they are medically necessary. A person's doctor can advise them on how often they recommend treatment. The individual can then check their plan to ensure that coverage is available.
Typically, the claim for Ankylosing Spondylitis is generally disability-oriented. Depending on your condition's severity, you may be entitled to partial or total disability claim. You can claim disability for Ankylosing Spondylitis through Personal Independence Payment ( PIP) which can assist with extra living costs.