Serious side effects Stop taking rosuvastatin and call a doctor or contact 111 if: you get unexplained muscle pain, tenderness, weakness or cramps – these can be signs of muscle breakdown and kidney damage. This can happen a few weeks or months after you first start taking this medicine.
Rosuvastatin is safe to take for a long time. In fact, it works best when you take it for a long time.
As you are aware, on March 4th of this year, we petitioned the FDA to ban the recently-marketed cholesterol-lowering drug rosuvastatin (Crestor/AstraZeneca) because of seven post-marketing cases of life-threatening rhabdomyolysis and nine cases of renal failure or renal insufficiency, both of which problems had also ...
Avoid eating foods high in fat or cholesterol, or rosuvastatin will not be as effective. Avoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage. Some antacids can make it harder for your body to absorb rosuvastatin.
Muscle and Kidney Damage
The most common side effects for statin patients affect the muscles. Myalgia is the most common of the muscle-related side effects. The risk increases in patients 65 years and older. Patients with kidney impairment are also at an increased risk for myalgia.
have ever had an allergic reaction to rosuvastatin or any other medicine. have liver or kidney problems. are trying to get pregnant, are already pregnant or are breastfeeding. have lung disease.
If you've made lifestyle changes through diet and exercise that have lowered your cholesterol levels, you may not need to continue taking a statin. These changes can help reduce your risk of heart attack, stroke, or blocked arteries while allowing you to take one less medication.
If you're taking a statin medication to lower your cholesterol, you will need to keep taking your prescription, or your cholesterol will likely go back up. Stopping your statin can put you at risk of having heart disease and other preventable health problems like stroke and heart attack from high cholesterol.
You'll usually take rosuvastatin for life. The benefits of the medicine will only continue for as long as you take it. You may want to stop rosuvastatin if you think you're having side effects. Talk to your doctor first to see if it really is a side effect of rosuvastatin or an unrelated problem.
Weight gain and weight loss are not known side effects of rosuvastatin. People taking the drug in clinical trials did not report weight changes. Sometimes, your doctor may recommend taking rosuvastatin along with changes in diet, such as limiting saturated fat.
Some statins, like rosuvastatin (Crestor), can lower your cholesterol levels more than other statins (if you compare them milligram to milligram). For example, rosuvastatin (Crestor) is considered a moderate-to-high intensity statin.
The current evidence, from well-run research trials of more than 100,000 patients, is that statins do not cause insomnia or any other sleep disturbance, compared with a dummy pill (placebo).
Adults—At first, 10 to 20 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 40 mg.
Anyone who wants to stop taking a statin should talk to a doctor. In some cases, coming off these drugs can be dangerous. The doctor may suggest reducing the dosage, combining the statin with another cholesterol lowering drug, or switching to another drug entirely.
High cholesterol levels are considered: too high: between 5 and 6.4mmol/l. very high: between 6.5 and 7.8mmol/l. extremely high: above 7.8mmol/l.
Most people can lower high cholesterol with lifestyle changes, like prioritizing heart-healthy foods, quitting tobacco products, exercising regularly, and sleeping enough. Making changes to lower your cholesterol might mean you don't need to take cholesterol medication anymore (or deal with the side effects).
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
If you quit cold turkey, your body can go into shock. It is not recommended that you stop statins suddenly if you have a history of heart attack or stroke, as it can put you at a higher risk of recurrent heart attack. You should speak with your doctor before stopping the medicine under any circumstance.
The FDA recommends rosuvastatin dosage reductions in Asian patients because pharmacokinetic studies have demonstrated an approximate two-fold increase in median exposure to rosuvastatin in Asian subjects when compared to Caucasian controls. Yet, no explanation for this ethnic difference has been confirmed.
Apotex discontinued production of all rosuvastatin presentations.