Natural and synthetic estrogen may cause the following common adverse effects: breast tenderness, nausea, vomiting, bloating, stomach cramps, headaches, weight gain, hyperpigmentation of the skin, hair loss, vaginal itching, abnormal uterine bleeding, also known as breakthrough bleeding, and anaphylaxis.
In addition to regulating the menstrual cycle, estrogen affects the reproductive tract, the urinary tract, the heart and blood vessels, bones, breasts, skin, hair, mucous membranes, pelvic muscles, and the brain.
Your body needs estrogen for your reproductive, cardiovascular and bone health. Too much estrogen, though, can cause irregular periods and may worsen conditions that affect your reproductive health. Your provider can help diagnose what's causing your high estrogen levels and recommend treatments that can help.
The first changes you will probably notice are that your skin will become a bit drier and thinner. Your pores will become smaller and there will be less oil production. You may become more prone to bruising or cuts and in the first few weeks you'll notice that the odors of your sweat and urine will change.
Estrogen regulates the growth, development, and physiology of the human reproductive system. This hormone also influences neuroendocrine, skeletal, adipose, and cardiovascular systems. Estrogen is an important sex hormone produced primarily by the ovaries in females and testes in males.
Estrogen therapy can help decrease your risk of certain health conditions, including osteoporosis, heart disease, stroke, dementia and mood changes.
Estrogen is a hormone that play a role in both the male and female reproductive systems. In females, it contributes to reproductive and breast health, among other functions. Estrogen contributes to cognitive health , bone health, the function of the cardiovascular system , and other essential bodily processes.
Estrogen promotes the storage of fat for healthy reproductive years. When estrogen is balanced, the right amount of fat helps carry out female reproductive functions. However, when there's too little or too much estrogen, weight gain often results.
Estrogen helps protect the heart from disease, potentially by maintaining higher levels of good cholesterol, called high-density lipoprotein (HDL), in your blood. Lower estrogen levels, especially during menopause, can increase your risk of developing heart disease.
Side effects of oestrogen
breast tenderness or swelling. swelling in other parts of the body. feeling sick. leg cramps.
Elevated estrogen levels in women have been linked to conditions such as polyps, fibroids, PCOS, endometriosis pain, and ovarian tumors [1]. Other conditions associated with high estrogen levels include dementia, heart disease, breast cancer, ovarian cancer, insulin resistance, and uterine cancer [4,6].
Genes associated with follicle growth were not significantly altered by vitamin D3. However, it increases expression of genes involved in the estrogen-biosynthesis. Further, estrogen concentrations in porcine granulosa cell-cultured media increased in response to vitamin D3.
Estrogen signaling affects aggressive interactions, as well as several behaviors that are closely linked with aggression, including sexual behavior, communication, and learning and memory.
Estrogen can reduce menopausal symptoms like hot flashes, night sweats and vaginal dryness. If you have a uterus, you'll likely need to take progesterone along with the estrogen. Estrogen without progesterone increases the risk of uterine cancer.
As estrogen levels drastically change in perimenopause, high levels can cause bloating, breast tenderness, and heavy bleeding. Once these levels become more consistently low, that can cause hot flashes, night sweats, mood changes, changes in fat distribution (new or growing “spare tire”), insomnia, and fatigue.
How Estrogen Replacement Therapy Can Help with Belly Fat During Menopause. Recent studies show that menopausal women on hormone therapy tend to have less body fat, especially visceral belly fat. Because estrogen affects how your body distributes fat, low estrogen levels can contribute to gaining fat in your belly area.
Many women also notice an increase in belly fat as they get older — even if they aren't gaining weight. This is likely due to a decreasing level of estrogen, which appears to influence where fat is distributed in the body.
Some evidence suggests that estrogen hormone therapy increases a woman's resting metabolic rate. This might help slow weight gain. Lack of estrogen may also cause the body to use starches and blood sugar less effectively, which would increase fat storage and make it harder to lose weight.
Hot flashes, flushes, and night sweats are the most common symptoms of low estrogen. At times, blood rushes to your skin's surface. This can give you a feeling of warmth (hot flash). Your face may look flushed.
The hormonal peaks have been found to occur in the morning for progesterone, in the afternoon for FSH and LH, and during the night for oestradiol. These findings are unlikely to alter the time of day we order female reproductive hormone measurements.
Estrogen is an important hormone that spurs your sexual development and helps maintain your reproductive system. It plays an essential role in other body systems, too. Estrogen levels rise and fall throughout your life, often in sync with other hormones that control important body processes, like your menstrual cycle.