Squamous cell carcinoma of the skin is usually not life-threatening, though it can be aggressive. Untreated, squamous cell carcinoma of the skin can grow large or spread to other parts of your body, causing serious complications.
Squamous cell carcinoma rarely metastasizes (spreads to other areas of the body), and when spreading does occur, it typically happens slowly. Indeed, most squamous cell carcinoma cases are diagnosed before the cancer has progressed beyond the upper layer of skin.
Most squamous cell carcinomas (SCCs) of the skin can be cured when found and treated early. Treatment should happen as soon as possible after diagnosis, since more advanced SCCs of the skin are more difficult to treat and can become dangerous, spreading to local lymph nodes, distant tissues and organs.
Most (95% to 98%) of squamous cell carcinomas can be cured if they are treated early. Once squamous cell carcinoma has spread beyond the skin, though, less than half of people live five years, even with aggressive treatment. There are many ways to treat squamous cell carcinoma that has not spread.
In general, the squamous cell carcinoma survival rate is very high—when detected early, the five-year survival rate is 99 percent. Even if squamous cell carcinoma has spread to nearby lymph nodes, the cancer may be effectively treated through a combination of surgery and radiation treatment.
Chemotherapy. Chemotherapy uses powerful drugs to kill cancer cells. If squamous cell carcinoma spreads to the lymph nodes or other parts of the body, chemotherapy can be used alone or in combination with other treatments, such as targeted drug therapy and radiation therapy.
Squamous Cell Carcinoma Early Stages
At first, cancer cells appear as flat patches in the skin, often with a rough, scaly, reddish, or brown surface. These abnormal cells slowly grow in sun-exposed areas.
For small, early SCCs that have not spread, excisional surgery is frequently the only treatment required. For advanced SCCs, the physician will most likely recommend additional treatments following removal of the tumor.
The key warning signs are a new growth, a spot or bump that's getting larger over time, or a sore that doesn't heal within a few weeks. (See Signs and Symptoms of Basal and Squamous Cell Skin Cancer for a more detailed description of what to look for.)
Squamous cell carcinoma of the skin is usually not life-threatening, though it can be aggressive. Untreated, squamous cell carcinoma of the skin can grow large or spread to other parts of your body, causing serious complications.
Systemic chemotherapy is not widely used for treating squamous cell carcinoma. In most cases, the cancer cells are confined to one area of skin and, if detected early, can be effectively addressed with localized treatments, such as surgery.
Stage 2 squamous cell carcinoma
In stage 2, the cancer is larger than 2 centimeters across, and has not spread to nearby organs or lymph nodes, or a tumor of any size with two or more high risk features.
Yes, squamous cell carcinoma can make you feel tired. It can make a person feel weak and exhausted. During the treatment procedures of squamous cell carcinoma, the patient tends to feel more tired. These types of fatigue that are related to cancer are known as cancer-related fatigue (CRF).
Although squamous cell carcinoma can be more aggressive than basal cell cancer, the risk of this type of cancer spreading is low—as long as the cancer is treated early, Dr. Leffell says. He notes that the lesions must be treated with respect because they may grow rapidly and invade deeply.
If you've had SCC, you have a high chance of recurrence. You also have an elevated risk of developing another SCC or basal cell carcinoma (BCC), since sun damage is the primary cause of both forms of skin cancer. If you have had a previous diagnosis of BCC, you also have a greater chance of developing SCC.
In general, the squamous cell carcinoma survival rate is very high—when detected early, the five-year survival rate is 99 percent. Even if squamous cell carcinoma has spread to nearby lymph nodes, the cancer may be effectively treated through a combination of surgery and radiation treatment.
On average, most people will recover within two to four weeks after treatment to remove cancer from their body. Your healthcare provider will meet with you a few weeks after treatment to make sure your body is healing properly and to make sure treatment was successful at removing cancer.
Radiation therapy: Radiation can target cancer cells in the skin, lymph nodes, or other areas of the body. When a patient has advanced squamous cell skin cancer, radiation therapy is often used along with another treatment. Immunotherapy: This type of treatment helps your immune system fight the cancer.
Diagnosis of squamous cell carcinoma
Squamous cell carcinoma is most curable in the early stages before it spreads. If it's diagnosed early, the five-year survival rate is approximately 99%.
Large size (>2 cm). Thick or deeply invasive lesion (>4 mm).
Squamous cell carcinomas arise from keratotic patches and become more nodular and erythematous with growth, sometimes including keratin plugs, horns, or ulceration. Because they may metastasize, they often are treated with excisional biopsy.
Squamous cell cancer can be aggressive, and our surgeons may need to remove more tissue. They may also recommend additional treatments for advanced squamous cell cancer, such as medications or radiation therapy—energy beams that penetrate the skin, killing cancer cells in the body.
As you have seen, squamous cell carcinoma can be deadly, although in many more cases, is disfiguring and unpleasant if left to develop.