The administration of metformin, as glucophage retard, at bedtime instead of supper time may improve diabetes control by reducing morning hyperglycemia.
It's best to take metformin tablets with, or just after, your evening meal to reduce the chance of getting side effects. Swallow your metformin tablets whole with a drink of water. Do not chew them.
This medicine is not recommended in patients 80 years of age and older who have kidney problems.
Taking metformin at night
If you're taking extended-release metformin, you should take your dose once daily at night, with your last meal of the day. Doing so allows the drug to work properly in reducing your blood sugar level.
Extended-release metformin is taken once a day and should be taken at night, with dinner. This can help to treat high glucose levels overnight.
Metformin should be taken with meals to help reduce stomach or bowel side effects that may occur during the first few weeks of treatment. Swallow the tablet or extended-release tablet whole with a full glass of water. Do not crush, break, or chew it.
You'll have more energy as your body uses insulin more efficiently. Common diabetes-related symptoms, such as blurry vision, being thirsty all of the time, or having to pee a lot, improve or disappear.
The administration of metformin, as glucophage retard, at bedtime instead of supper time may improve diabetes control by reducing morning hyperglycemia.
Metformin does not instantly reduce blood sugar levels. The effects are usually noticeable within 48 hours of taking the medication, and the most significant effects take 4–5 days to occur. However, the timing depends on the person's dosage.
Taking metformin can cause vitamin B12 deficiency if you take it for a long time. This can make you feel very tired, breathless and faint, so your doctor may check the vitamin B12 level in your blood. If your vitamin B12 levels become too low, vitamin B12 supplements will help.
As much as possible, avoid white bread, white rice, white pasta, candy, soda, desserts, and snacks like chips or crackers. Eating foods that can spike your blood sugar will not necessarily make the metformin not work, however, it will increase the burden it has to work against.
Taking certain other medications with metformin may increase the risk of lactic acidosis. Tell your doctor if you are taking acetazolamide (Diamox), dichlorphenamide (Keveyis), methazolamide, topiramate (Topamax, in Qsymia), or zonisamide (Zonegran).
Luckily, metformin may start to work within the first week of treatment. In one study of over 700 people, metformin ER lowered blood glucose within the first week of treatment. But it took about 2 months for it to have its full glucose-lowering effect.
As already discussed, metformin can result in sleep disturbance, and this might affect normal dream patterns. Nightmares are reported in patients receiving metformin.
-It acts on intestines and reduces the absorption of sugar. To overcome these side-effects, it is better to take it with meals or just after finishing meals. This helps to reduce some of these side-effects. Thus, it is advisable to take metformin with meals or just after finishing meals.
Conclusion. We showed that metformin therapy is associated with a longer sleep duration and better sleep efficiency. Randomized clinical trials are needed to confirm metformin's favourable effect on sleep quality and quantity.
Metformin helps lower how much sugar gets absorbed through your intestines, which means that less sugar makes it to your bloodstream. It lowers sugar production. You get sugar from the foods you eat, but did you know that your body naturally produces sugar, too? Most of this happens in the liver.
Official answer. Metformin (brand name: Glucophage) will be in your system for 96.8 hours which is approximately 4 days. Metformin has an elimination half-life of approximately 17.6 hours.
It could be that you are not following dietary guidelines, have stopped exercising, or have gained excessive weight. Or, it could be that you're not taking the drug as prescribed. Whatever the reason, the very first indication that metformin is not working is when your blood glucose levels are high.
Should you drink a lot of water when consuming this medicine? Metformin must be consumed with meals to assist lower stomach or bowel side effects that might happen during the initial few weeks of treatment. The tablet or extended-release tablet must be taken whole with a full glass of water.
Many studies have demonstrated that once or twice daily administration of ER metformin is as safe and efficacious as twice daily IR metformin, overall providing continued glycemic control for up to 24 weeks of treatment [5].
Under certain conditions, too much metformin can cause lactic acidosis. The symptoms of lactic acidosis are severe and quick to appear, and usually occur when other health problems not related to the medicine are present and are very severe, such as a heart attack or kidney failure.
Many of these mild symptoms are associated with taking the medicine for the first time. The common side effects of metformin include diarrhea, nausea, upset stomach, dizziness, headache and taste disturbance. However, these side effects generally go away after you take the medication for a while.