Yes, there have been reports and concerns about lawsuits and adverse events related to NexGard (afoxolaner) and other isoxazoline flea/tick products, primarily stemming from the FDA's alerts regarding potential neurological side effects like seizures and tremors in some dogs and cats, leading to consumer complaints and class-action discussions, though the products remain approved as generally safe when used as directed, according to the FDA and manufacturers, the AVMA, and NexGard's official FAQ page.
Nexgard is generally a very safe product and one of the most effective flea and tick control products on the market. However, it is important not to use this class of drug in dogs with epilepsy as it can increase their risk of seizures if they have epilepsy. In healthy dogs without epilepsy, it works wonderfully.
These products are safe to use in the majority of pets, but there are some pets that cannot tolerate the medication (specific liver disorders, pre-existing seizure disorders).
The most frequently reported adverse reactions include vomiting, application site reactions, lethargy, and anorexia.
Nexgard can cause side effects like lethargy and loss of appetite, especially in older dogs. Symptoms include reduced energy, slower movement, and decreased interest in food or water. Monitor closely; if symptoms worsen or persist beyond 24-48 hours, seek emergency veterinary care.
Puppies who are under eight weeks of age or dogs weighing less than four pounds should not take Nexgard. Nexgard is only available by prescription from your veterinarian.
The most common signs of toxicity from pyrethrum-based flea products are muscle tremors and excessive salivation. Common signs of organophosphate-based flea product toxicity include diarrhea, vomiting, difficulty breathing, small pupils, muscle tremors, weakness or falling over, and drooling.
Under many circumstances, newer dog flea collars are safe options for flea and tick control (unlike older collars, which were largely ineffective). The Seresto collar is a very popular and effective option. This collar uses flumethrin and imidacloprid to repel and kill fleas and ticks, so they don't bite pets.
Both products are safe for dogs when following directions and Nexgard has been approved by the FDA to treat and prevent flea and tick infestations. However, unlike Frontline Plus, Nexgard has not yet been evaluated for use in breeding, pregnant, or lactating dogs.
It's also recommended to prevent Lyme disease in dogs. NexGard comes in a chewable tablet and is usually given by mouth once monthly. The most risky side effect of NexGard is seizures or other neurologic symptoms. Dogs with a history of seizures should not take NexGard.
Popular, vet-recommended flea and tick medicines for dogs include chewables Simparica and Credelio, plus Bravecto topical, all of which are prescription medicines. Your vet can help you choose the best flea and tick medication for your individual dog based on their specific needs.
Both products are safe for dogs when following directions and have been approved by the FDA to treat and prevent flea and tick infestations. While Simparica was trialed and not approved, Nexgard has not yet been evaluated for use in breeding, pregnant, or lactating dogs.
NexGard chews contain afoxolaner. Once administered, it is absorbed into the bloodstream. When fleas and ticks ingest blood containing afoxolaner, it causes hyperexcitation and kills the parasite.
Secondly, Bravecto and NexGard are trusted by veterinarians for their efficacy and safety, offering pet parents peace of mind. Both treatments are also suitable for use in young dogs, allowing for early protection against fleas and ticks.
In short, yes, your dog needs flea and tick prevention during the winter months. While it's true that tick and flea species slow down during the winter when outdoor temperatures drop, fleas can easily find their way in your home and onto your pet during the winter.
Fleas and ticks can carry and transmit diseases, which is why preventing infection is important. Preventatives are types of medication that can be safely and routinely given to deter fleas and ticks from biting your dog.
Our top pick for flea and tick prevention is K9 Advantix II, an OTC topical medicine you apply monthly. In addition to repelling and killing fleas and ticks, it also protects against mosquitoes, which can transmit heartworms.
A few brands of medicated flea collars are available, but the Seresto® collar by Elanco™ is the only one with appropriate safety and efficacy studies and is most recommended by veterinarians to pet parents looking for a flea collar. Flea collars are available for both dogs and cats.
NexGard chews are FDA-approved to prevent Lyme infections in dogs as a result of killing black-legged ticks. And studies show that dogs prefer NexGard chews over other chews. *2NexGard chews are safe for puppies as young as 8 weeks, weighing 4 pounds or more.
Dogs can also become exposed at toxic quantities through the ingestion or absorption of household insect sprays, foggers, and granules. Common brands of pyrethrins/pyrethroids include: Advantix™ Vectra 3D®
Cedarwood oil solution (10 drops per 1 ounce of water) can be applied to both pets and the environment once to twice daily. Cedarwood mulch is a helpful deterrent for landscaping. For moderate infestations, Dr. Trish uses Revolution and for severe infestations, she recommends Nexgard.
As many of you know, Frontline Gold was discontinued last year. However, Frontline Plus is still on the market and available for purchase on our online webstore for those of you who prefer topical applications!
Toxicity in dogs can show up anywhere from minutes to several days or even months after exposure, depending entirely on the substance; some toxins (like alcohol or certain pesticides) are rapid, causing symptoms like drooling or seizures quickly, while others (like some rat poisons) cause delayed internal bleeding over days, requiring immediate veterinary attention even if the dog seems fine. Always contact your vet or the Pet Poison Helpline (855-764-7661) immediately if you suspect poisoning, even without symptoms.
Severe reactions to flea and tick medications can lead to neurological damage, breathing problems, or organ issues if not treated quickly. Toxicity can cause dangerous seizures that may not stop without medical help. In severe cases, these reactions can affect the nervous system and lead to breathing difficulties.
NexGard chewables contain an active ingredient that is not evenly distributed, making splitting doses unsafe.