Simparica Trio is the brand name of a chewable tablet that protects dogs from heartworm disease, fleas, five species of ticks, and two types of intestinal parasites. Manufactured by Zoetis, Simparica Trio contains three drugs: sarolaner, moxidectin, and pyrantel pamoate.
Simparica Trio is a veterinary medicine used to treat dogs with flea or tick infestations and roundworm or hookworm infections in the gut. At the same time, Simparica Trio is used to prevent heartworm and lungworm disease (both caused by blood worms that infect the heart and blood vessels supplying the lungs).
If any dog determined by a licensed veterinarian to be free of heartworm infection at the onset of treatment with Simparica Trio develops heartworm disease, we will provide reimbursement (up to $1,000 and provide Diroban® (melarsomine dihydrochloride) or provide reasonable acquisition costs of melarsomine ...
Use with caution in dogs with a history of seizures or neurologic disorders. Prior to administration of SIMPARICA TRIO, dogs should be tested for existing heartworm infections. Infected dogs should be treated with an adulticide to remove adult heartworms.
If you're hoping to find a broad-spectrum product that protects against fleas and ticks while it defends against internal parasites, Simparica Trio is the clear winner. However, if your dog is already taking a flea and tick preventative, your vet might suggest concomitant use of Heartgard Plus.
Final Thoughts. As you can see, both Nexgard and Simparica are extremely good and effective flea and tick treatment and they do not have a major difference between them. But that being said, Simparica does kill an additional tick specie and is relatively faster in eliminating fleas and ticks.
Simparica TRIO is a tasty monthly chew that provides triple protection against a trio of the biggest threats facing our dogs. Fleas and ticks, intestinal worms and deadly heartworm.
IMPORTANT SAFETY INFORMATION Use with caution in dogs with a history of seizures. Simparica Trio contains sarolaner, a member of the isoxazoline class, which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in dogs with or without a history of neurologic disorders.
Both products are safe for dogs when following directions and have been approved by the FDA to treat and prevent flea and tick infestations. While Simparica was trialed and not approved, Nexgard has not yet been evaluated for use in breeding, pregnant, or lactating dogs.
The cumulative deaths reported to April 2021 ranged from a high of 2,627 (24%) for fluralaner (Bravecto®) to 726 (2.8%) for afoxolaner (NexGard®) and 412 (12.7%) for sarolaner (Simparica®).
Simparica Trio is a popular parasite treatment because it tackles many common dog parasites all in one go, including ticks and fleas, roundworms and hookworms, and even heartworm disease. Developed by Zoetis, Simparica Trio is just one possible option for parasite control and prevention across the market.
Nexgard Spectra, Credelio Plus, and Simparica Trio cover fleas, heartworm, intestinal worms - and ticks. The only major parasite that none of them cover is the hydatid tapeworm - this is spread via consumption of infected animal carcasses or raw offal.
Simparica is an excellent choice for flea and tick protection. The monthly chew also comes with an option for heartworm protection, too, as Simparica Trio. But while Simparica is usually safe flea and tick treatment for dogs, it shouldn't be prescribed to dogs with a history of seizures.
How long does Simparica protection last? Simparica is a monthly chewable that starts protecting in hours* and lasts for 35 days.
Additionally, the chemicals in some flea treatments can be irritating to dogs, leading to discomfort and restlessness. Finally, some dogs may experience an allergic reaction to the ingredients in flea medicine, which can also lead to restlessness.
Melarsomine dihydrochloride (available under the trade names Immiticide and Diroban) is an arsenic-containing drug that is FDA-approved to kill adult heartworms in dogs. It's given by deep injection into the back muscles to treat dogs with stabilized class 1, 2, and 3 heartworm disease.
Both products are safe for dogs when following directions and have been approved by the FDA to treat and prevent flea and tick infestations. However, unlike Bravecto, Simparica has yet to be approved for use in breeding, pregnant, or lactating dogs.
Since these products have obtained their respective FDA approvals, data received by the agency as part of its routine post-marketing activities indicates that some animals receiving Bravecto, Nexgard or Simparica have experienced adverse events such as muscle tremors, ataxia, and seizures.
That same information showed 720 reported seizures for Bravecto in four years and 557 for Simparica in three years. For Credelio, six seizures were reported in the first six months after its approval. The manufacturers said the risk of side effects is rare, less than one in 10,000 doses sold.
There are 720 reported seizures for Bravecto in four years, 557 for Simparica in three years, and six seizures for Credelio in the first six months after is was approved. The manufacturers says the risk of side effects is very rare, less than one in 10,000 doses sold.
Simparica Trio is the brand name of a chewable tablet that protects dogs from heartworm disease, fleas, five species of ticks, and two types of intestinal parasites. Manufactured by Zoetis, Simparica Trio contains three drugs: sarolaner, moxidectin, and pyrantel pamoate.
Your dog's health status: While Simparica Trio is generally safe for most dogs, there are some medical conditions that may make it unsuitable. If your dog has a history of seizures, liver or kidney disease, or is pregnant or nursing, you should consult with your veterinarian before administering Simparica Trio.
SIMPARICA TRIO is given orally once a month, at the recommended minimum dose of 0.54 mg/lb (1.2 mg/kg) sarolaner, 0.011 mg/lb (24 μg/kg) moxidectin, and 2.27 mg/lb (5 mg/kg) pyrantel (as pamoate salt). SIMPARICA TRIO can be offered to the dog with or without food.