It's usually recommended that a course of antidepressants continues for at least 6 months after you feel better, to prevent your condition recurring when you stop. Some people with recurrent illness are advised to carry on taking medicine indefinitely.
For people with chronic or severe depression, medication may be needed on a long-term basis. In these cases, antidepressants are often taken indefinitely. That is, in part, because depression is not an illness that can be cured.
Those who had used antidepressants for >3 years reported more severe side effects, including “weight gain”, “addiction”, “feeling not like myself ”, “withdrawal symptoms”, and “suicidality”, than those who had been on antidepressants for ≤2 years.
Guidance from the National Institute of Health and Care Excellence recommends that antidepressants are used as 'maintenance' treatment for up to 2 years to prevent their depression returning (relapse). It also recommends cognitive-behavioural therapy to change habits of thought and behaviour.
It's usually recommended that a course of SSRIs continues for at least 6 months after you feel better, to prevent your condition coming back when you stop. However, if you've experienced previous episodes of depression, a 2-year course may be recommended.
The length of treatment varies.
Even once you do start to feel better, you should expect to remain on your antidepressant for at least 4 to 6 additional months. Those experiencing depression for the first time may require even longer, from 6 to 12 months.
You are feeling better, and you and the doctor agree that it is time to stop. You have been taking the medicine for at least 6 months after you feel better. You are having counselling to help you cope with problems and help change how you think and feel. You are not worried about the depression coming back.
If the symptoms develop later or gradually, they may constitute a relapse of the depression. Ultimately, these withdrawal symptoms will improve with time, but they can be unpleasant for days and possibly even weeks. In time, the brain readjusts and people should experience a return to their normal state.
If you feel like your antidepressant has stopped working, you're not alone. It's common for a medication that once worked wonders to become ineffective, especially if you've been taking it for a long time. Symptoms return for up to 33% of people using antidepressants — it's called breakthrough depression.
Take your time.
You may be tempted to stop taking antidepressants as soon as your symptoms ease, but depression can return if you quit too soon. Clinicians generally recommend staying on the medication for six to nine months before considering going off it.
Clinicians generally recommend staying on the medication for six to nine months before considering going off antidepressants. If you've had three or more recurrences of depression, make that at least two years.
Long-term antidepressant users are risking permanent damage to their bodies, according to leading medical experts. Dr Tony Kendrick, a professor of primary care at the University of Southampton, says more urgent action needs to be taken to encourage and support long-term users to come off the medication.
The risks appear to climb as people age. In older adults, SSRI medications are associated with falls and fractures. Some studies have found a link between SSRI use and a higher risk of dementia.
While there is limited research on long-term antidepressant treatment, the antidepressant medications are some of the most commonly prescribed medications in the world, and there is substantial experience. Evidence indicates that these medications cause changes that persist only as long as medications are taken.
Discontinuing an antidepressant medication usually involves reducing your dose in increments, allowing two to six weeks or longer between dose reductions. Your clinician can instruct you in tapering your dose and prescribe the appropriate dosage pills.
If you decrease your daily calorie intake as a result, you could potentially lose weight by stopping your antidepressants. On the other hand, if you experience loss of appetite with depression, and your depression comes back after stopping antidepressants, you may also lose weight.
Do Antidepressants Permanently Alter Brain Chemistry? Antidepressants are designed to alter brain chemistry to alleviate symptoms—thus, they do so while you are taking them. They may promote potentially beneficial structural brain changes, as well.
Antidepressants are usually taken daily. The goal in the first few weeks and months is to relieve the symptoms and, where possible, make the depression go away. Once that has been achieved, the treatment is continued for at least four to nine months.
7) Do I have to take my anxiety medication for life? Not always. It depends on your symptoms and how controlled they become over time. As mentioned, if you're taking an antidepressant, it may take a few weeks before your symptoms improve.
New evidence shows some anti-depressants can raise dementia risk. Certain antidepressants and bladder medications are linked to increased risk of dementia, according to new University of East Anglia research funded by Alzheimer's Society and published today in the British Medical Journal.
The few studies of antidepressant withdrawal that have been published suggest that it is harder to get off some medications than others. This is due to differences in the drugs' half-life — the time it takes the body to clear the medication once the pills are stopped.
If you have a form of anxiety or phobia, an antidepressant could help you feel calmer and more able to deal with other problems. It could also help you feel more able to benefit from other anxiety treatments, such as cognitive behavioural therapy (CBT).
What are the most common antidepressants? Sertraline hydrochloride, used for multiple mental health and mood disorders, is the most prescribed antidepressant on the list with more than 18 million prescriptions in 2021.