Serious side effects include allergic reactions, signs of abnormal bleeding such as prolonged bleeding or bruising easily, nausea, gut pain, or numbness. pharmacist if you would like further information or if you have any concerns or questions about using Clexane.
It is safe to take painkillers such as paracetamol, co-codamol or codeine if you are using Clexane. However, it is best to avoid non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, diclofenac, naproxen (unless you have been prescribed them by your doctor.
Response and effectiveness. The average time to peak effects on various clotting factors is anti-Xa (3 hours), anti-IIa (4 hours), and Heptest (2.5 hours). Activity against anti-Xa persists for about 12 hours following a once-daily dose of enoxaparin 40mg.
Are there any side effects? Less serious side effects include pain, bruising, bleeding, swelling, itch, or rash at the injection site. Serious side effects include allergic reactions, signs of abnormal bleeding such as prolonged bleeding or bruising easily, nausea, gut pain, or numbness.
Clexane is given either once or twice daily, depending on the underlying medical condition. Patients with mechanical heart valves are more likely to need an injection both morning and night.
Make sure you take the clexane at the same time every day. If you need to have an injection twice a day then give the first dose in the morning and second dose 12 hours later. Sit or lie in a comfortable position so you are relaxed.
The approach combines Clexane with the steroid Prednisone. Injections continue until at least 12 weeks gestation. The research suggests a 53% pregnancy rate.
In patients with high risk of thromboembolism, a CLEXANE dosage of 40 mg (0.4 mL; anti-Xa: 4000 IU) should be administered subcutaneously once daily. In high risk patients undergoing surgery, the initial dose should be given approximately 12 hours preoperatively or 12 hours postoperatively.
Aside from bleeding-related issues, there are several side effects that have been linked to blood thinners, such as nausea and low counts of cells in your blood. Low blood cell count can cause fatigue, weakness, dizziness and shortness of breath. Be careful mixing medications.
Because you are taking a blood thinner, you should try not to hurt yourself and cause bleeding. You need to be careful when you use knives, scissors, razors, or any sharp object that can make you bleed. You also need to avoid activities and sports that could cause injury. Swimming and walking are safe activities.
Common side effects of anticoagulants include stomach upset, loss of appetite, bloating, and diarrhea. If the dosage is too high, blood may be seen in the urine or stool or around the gums, or frequent nosebleeds may occur.
Direct subcutaneous injection should be given into a subcutaneous tissue skinfold of the abdomen or the upper-outer aspect of the thigh. The skinfold should be held throughout the injection. After removal of the needle, do not rub the site. Rather, place firm, even pressure to the site of injection for 1-5 minutes.
If you do drink alcohol, it is recommended to not have more than 2 drinks (can of beer, glass of wine, shot of spirit) per day for men or 1 drink per day for women. You may have a higher risk for bleeding if you drink more alcohol than this.
Clexane should be injected into the layer of fat just under the skin (subcutaneous administration) in your abdomen. Clexane should never be injected into muscle as bleeding into the muscle may occur.
After delivery, women with clotting disorders need to resume anticoagulation or blood thinner therapy. Women need to continue taking anticoagulants for at least six weeks post-delivery, either injections or an oral anticoagulant, as the risk for bleeding is reduced, to protect themselves from blood clots.
Clexane stops unwanted blood clots from forming and can stop any blood clots that have already formed from growing bigger. Clexane does NOT break down blood clots that have already formed. Clexane acts as a roadblock, interfering with how the process of blood clotting occurs.
Clexane/heparin
Heparin acts through several pathways to prevent the formation of blood clots in blood vessels. In women with clotting problems, this could potentially prevent clots forming in the placenta, and so reduce miscarriage and increase live births.
Clexane Multidose Vial should be injected just under the skin on your stomach, but not too near the belly button or any scar tissue (at least 5cm away from these).
Extensive bruising on the abdomen or site of injection may mean you are not injecting it correctly. Please call your pharmacist or doctor for medical advice if you observe extensive or worsening bruises.
You should take the injection as close to the time the flight leaves as possible. This is because LMWH has an instantaneous effect, but only lasts for 12-24 hours. If you have a very long haul flight, you may need to inject for a second time after 24 hours.
Unless told by a doctor, do not give Aspirin, anti-inflammatory medicines (eg Nurofen), or herbal remedies to children receiving clexane. Clexane makes the risk of bleeding bigger, so contact sports should be avoided (e.g. football, rugby, martial arts).
It can cause a rapid decrease in blood pressure, which may be dangerous to the patient.