To slow dementia, focus on lifestyle factors like regular physical and mental activity, social connection, a heart-healthy diet, managing chronic conditions (blood pressure, cholesterol, weight), quitting smoking, good sleep, and protecting your head and hearing, alongside medications prescribed by a doctor to manage symptoms and slow decline. Building a "cognitive reserve" through lifelong learning and new challenges strengthens brain connections, helping it cope better with disease.
There is no known cure, but early diagnosis and treatment can lead to better quality of life. Stay healthy with a good diet and regular exercise. Stay away from alcohol and other substances that may affect memory, thinking, and behavior.
Reduce your risk of dementia
You can live with dementia for an average of 4 to 10 years after diagnosis, but this varies significantly, with some people living 20 years or more, depending on age, overall health, and dementia type, with Alzheimer's averaging 8-10 years and vascular dementia closer to 5 years. Factors like diagnosis stage, age, gender, other health conditions (e.g., heart disease, frailty), and dementia subtype greatly influence life expectancy, with people often succumbing to infections or complications rather than the disease itself.
There is growing evidence that exercise also protects the brain from dementia, especially when combined with a healthy diet and treatment of risk factors for cardiovascular disease. Some research also shows that physical activity might slow the progression of altered thinking in people with Alzheimer's disease.
Foods containing high levels of antioxidants such as berries and kiwis are effective in helping to prevent and reduce inflammation. Colorful vegetables, dark chocolate and turmeric can also go a long way in protecting the brain from early onset dementia.
The cause of roughly 70% of all dementia cases is Alzheimer's disease, a progressive brain disorder characterized by the buildup of amyloid plaques and tau tangles, leading to memory loss and impaired thinking that interferes with daily life, making it the most common form of dementia.
Signs of late-stage dementia
having a limited understanding of what is being said to them. needing help with most everyday activities. eating less and having difficulties swallowing.
Donepezil (also known as Aricept), rivastigmine (Exelon) and galantamine (Reminyl) are used to treat the symptoms of mild to moderate Alzheimer's disease. Donepezil is also used to treat more severe Alzheimer's disease.
The three golden rules for communicating with someone with dementia, often from the SPECAL method, are: Don't ask direct questions, Listen to the expert (the person with dementia) and learn from them, and Don't contradict, which means avoiding arguments and validating their feelings instead of focusing on facts. These rules help reduce confusion and distress, creating a calmer, more compassionate interaction by shifting focus from factual accuracy to emotional connection.
What Can You Do?
We all inherit a copy of some form of APOE from each parent. Those who inherit one copy of APOE-e4 from their mother or father have an increased risk of developing Alzheimer's. Those who inherit two copies from their mother and father have an even higher risk, but not a certainty.
The 10 warning signs of dementia include memory loss, difficulty with familiar tasks, confusion about time/place, trouble with language, poor judgment, misplacing things, personality changes, loss of initiative, and problems with visual/spatial skills, requiring professional assessment to distinguish from normal aging.
Smoking, low physical activity, and a poor diet are all lifestyle and environmental influences that have been linked to rapid dementia decline. Physical activity promotes cardiovascular health, which in turn improves brain function. Those who lead a sedentary lifestyle may experience faster cognitive decline.
When someone gets the diagnosis of dementia, a cure is only very rarely possible (see p2 About Reversible Dementias). In the current issue of Neurology, Sacks and Shulman1 report one of these rare cases of a reversal of dementia involving a patient on steroid medication.
For most people with Alzheimer's — those who have the late-onset variety — symptoms first appear in their mid-60s or later. When the disease develops before age 65, it's considered early-onset Alzheimer's, which can begin as early as a person's 30s, although this is rare.
Vitamin D supplements are linked to a significant reduction in dementia risk, with a major study showing users had a 40% lower incidence of developing dementia compared to non-users, particularly benefiting older adults, with even greater effects seen in women and those without existing cognitive issues. This reduction highlights Vitamin D's role in brain health, possibly by clearing amyloid plaques associated with Alzheimer's.
The number one cause of dementia is Alzheimer's disease, responsible for 60-80% of cases, characterized by brain plaques (beta-amyloid protein) and tangles (tau protein) that damage nerve cells, leading to progressive memory and cognitive decline, though vascular dementia from blood vessel damage is also a significant factor.
Donanemab, like lecanemab, is a type of drug called a monoclonal antibody. Antibodies form part of our immune system and bind to harmful proteins to destroy them. Donanemab contains antibodies that bind to a protein called amyloid, which builds up in the brain in the early stages of Alzheimer's disease.
The "2-finger test" for dementia involves an examiner showing a hand gesture (like interlocking index and middle fingers) and asking the patient to copy it, testing motor skills, visual memory, and coordination, as difficulties can signal early cognitive decline, but it's a screening tool, not a definitive diagnosis, prompting further medical evaluation. Other related tests include finger-tapping and finger-to-nose, looking for hesitation or misjudgment in movement.
other long-term health problems – dementia tends to progress more quickly if the person is living with other conditions, such as heart disease, diabetes or high blood pressure, particularly if these are not well-managed.
Playing music, having objects to touch and interact with, and hand massage can all help people with dementia in the later stages.
Our results confirm that vitamin D deficiency is associated with a substantially increased risk of all-cause dementia and Alzheimer disease.
The majority of dementia is not inherited by children and grandchildren. In rarer types of dementia there may be a strong genetic link, but these are only a tiny proportion of overall cases of dementia.
You Miss Out on Sleep
You do a few things you know you shouldn't -- we all do. But some of those bad habits can take a toll on your brain. For example, lack of sleep may be a cause of dementia, including Alzheimer's disease. It's best to have regular sleeping hours.