Vitiligo is generally considered to be an autoimmune disorder. Autoimmune disorders occur when the immune system attacks the body's own tissues and organs. In people with vitiligo the immune system appears to attack the pigment cells (melanocytes) in the skin .
Vitiligo is an autoimmune disease of the skin, which means that someone with vitiligo has an immune system that is malfunctioning in a small way.
Vitiligo occurs when immune cells destroy the cells that make brown pigment (melanocytes). This destruction is thought to be due to an autoimmune problem. An autoimmune disorder occurs when the body's immune system, which normally protects the body from infection, attacks and destroys healthy body tissue instead.
Here, we hypothesize that patients with non‐segmental vitiligo (NSV), an autoimmune skin (and mucosal) disorder, may clear SARS‐CoV‐2 infection more efficiently and have a lower risk of COVID‐19 development.
People with vitiligo may also have an increased risk of other autoimmune conditions, such as pernicious anemia, Addison's disease, and Sjögren's disease.
Several studies showed that vitiligo has been associated with autoimmune thyroid diseases, pernicious anemia, Addison's disease.
Vitiligo is associated with several comorbid autoimmune, systemic, and dermatological diseases, primarily thyroid disease, alopecia areata, diabetes mellitus, pernicious anemia, systemic lupus erythematosus, rheumatoid arthritis, Addison's disease, inflammatory bowel disease, Sjögren's syndrome, dermatomyositis, ...
There have been two previous case reports that have also indicated a temporal association between the COVID-19 vaccine and the development of new-onset vitiligo; one occurring in a 58-year-old man with a prior history of ulcerative colitis following the Pfizer vaccine and another occurring in a 61-year-old woman ...
About 15 to 25 percent of people with vitiligo are also affected by at least one other autoimmune disorder, particularly autoimmune thyroid disease, rheumatoid arthritis, type 1 diabetes, psoriasis , pernicious anemia, Addison disease, systemic lupus erythematosus, celiac disease, Crohn disease, or ulcerative colitis.
Many people who have vitiligo are often otherwise healthy. Even so, it's important to find a doctor like a dermatologist who knows about vitiligo. People who have vitiligo have a higher risk of getting some other medical conditions. You can also get painful sunburns on the skin that has lost color.
As non-segmental vitiligo is closely associated with other autoimmune conditions, you may be assessed to see whether you have any symptoms that could suggest an autoimmune condition, such as: being tired and lacking energy, which may be a sign of Addison's disease.
Vitiligo is a common pigmentary disorder caused by the destruction of functional melanocytes. Vitamin D is an essential hormone synthesized in the skin and is responsible for skin pigmentation. Low levels of vitamin D have been observed in vitiligo patients and in patients with other autoimmune diseases.
Protect your skin from the sun.
A bad sunburn can worsen vitiligo. If you have a lighter skin tone, there's another advantage to protecting your skin from the sun. Without a tan, the lighter spots and patches are often less noticeable.
In this study, vitiligo did not appear to be associated with a high body mass index, in contrast to most other autoimmune diseases.
No, vitiligo is not a form of lupus. Both are autoimmune conditions that can affect your skin. If you have one, you are more likely to get the other. But they are two different diseases with two different treatments.
Nevertheless, vitiligo has been found to be associated with chronic hepatitis C virus (HCV) infection and autoimmune hepatitis [17].
Pityriasis versicolor can sometimes be confused with vitiligo, as they both cause the skin to become discoloured in patches. But there are ways to tell the difference: vitiligo often develops symmetrically (on both sides of your body at the same time), while pityriasis versicolor may not.
Some wonder if the overactive nature of the immune response due to vitiligo will cause additional side effects to the vaccine, but it is unlikely because it's not the entire immune system that is hyperactive, just a small portion responsible for killing the pigment cells.
However, the temporal relationship between the vaccine and development of the disease and the instances of autoimmune phenomena manifesting after COVID‐19 vaccination, 1 , 2 , 5 , 6 suggest that the vaccine could play a role in triggering vitiligo.
Treatment cannot cure vitiligo.
While researchers are looking for a cure, treatment cannot currently cure this disease. Treatment can help restore lost skin color, but the color (repigmentation) may fade over time. To keep their results, many patients have maintenance treatments.
The one significant observation that we found to have the poor prognostic implication in vitiligo is the presence of mucosal vitiligo.
If a person has vitiligo, the risk that a first-degree family member (parent, child, or sibling) is 5%, or 5 times higher than the general population. That seems like a big increase, but even so, that means only about 1 in 20 first-degree relatives of vitiligo patients get vitiligo as well.
Vitiligo signs include: Patchy loss of skin color, which usually first appears on the hands, face, and areas around body openings and the genitals. Premature whitening or graying of the hair on your scalp, eyelashes, eyebrows or beard.